本文選題：單胃動(dòng)物　切入點(diǎn)：腸道菌群　出處：《動(dòng)物營養(yǎng)學(xué)報(bào)》2017年07期

【摘要】：單胃動(dòng)物的腸道中存在著龐大而復(fù)雜的菌群,它們與宿主腸道免疫系統(tǒng)協(xié)同進(jìn)化。腸道細(xì)菌及其代謝產(chǎn)物在維持腸道穩(wěn)態(tài)方面發(fā)揮著重要的作用。正常的腸道菌群能促進(jìn)免疫系統(tǒng)發(fā)育,參與維持宿主免疫功能,協(xié)同拮抗病原菌的增殖和入侵。反過來,宿主腸道免疫系統(tǒng)對(duì)腸道菌群又有制約和調(diào)控作用,如對(duì)正常共生菌表現(xiàn)為免疫耐受,對(duì)病原菌表現(xiàn)為免疫排斥。一旦這種動(dòng)態(tài)平衡被破壞,就會(huì)導(dǎo)致疾病的發(fā)生。本文綜述了單胃動(dòng)物腸道菌群與宿主腸道免疫系統(tǒng)的相互關(guān)系,并基于現(xiàn)有的研究結(jié)果,對(duì)其可能的互作機(jī)制做了較為系統(tǒng)的總結(jié)。
[Abstract]:Monogastric animals have a large and complex flora in their intestines, which coevolved with the host gut immune system.Intestinal bacteria and their metabolites play an important role in maintaining intestinal homeostasis.Normal intestinal flora can promote the development of immune system, participate in maintaining host immune function, and cooperate to antagonize the proliferation and invasion of pathogenic bacteria.On the other hand, the host intestinal immune system has the function of restricting and regulating the intestinal flora, such as immune tolerance to normal symbiotic bacteria and immune rejection to pathogenic bacteria.Once this dynamic balance is broken, it can lead to disease.In this paper, the relationship between intestinal flora of monogastric animals and the host intestinal immune system is reviewed, and the possible interaction mechanism is summarized based on the existing research results.
【作者單位】： 四川農(nóng)業(yè)大學(xué)動(dòng)物營養(yǎng)研究所動(dòng)物抗病營養(yǎng)教育部重點(diǎn)實(shí)驗(yàn)室;
【基金】：國家自然科學(xué)基金項(xiàng)目(3167131062)
【分類號(hào)】：S816

【相似文獻(xiàn)】

相關(guān)期刊論文 前1條

1 李凱年;逯德山;;益生素何以能夠促進(jìn)畜禽健康,提高生產(chǎn)性能——共生細(xì)菌可以調(diào)節(jié)動(dòng)物腸道免疫系統(tǒng)(上)——益生素在畜牧業(yè)應(yīng)用理論依據(jù)不斷完善前景日益廣闊[J];中國動(dòng)物保健;2009年04期

，

本文編號(hào)：1710516