發(fā)布時間：2018-04-01 18:59

  本文選題：脂肪和肥胖相關基因　切入點：FTO基因　出處：《西南農業(yè)學報》2017年11期

【摘要】：【目的】本文探討了FTO基因多態(tài)性與不同綿羊群體生長性狀的相關性�！痉椒ā坎捎蔑w行質譜技術檢測了FTO基因在杜泊羊和灘寒雜交群體中的多態(tài)性及其與生長性狀的相關性�！窘Y果】FTO基因的rs160915957位點的AA基因型個體體重在杜泊和灘寒綿羊群體中分別為極顯著(P0.01)和顯著(P0.05)低于GG型個體。GG型綿羊胸圍最大,且GG型杜泊羊胸圍顯著大于灘寒羊GG型個體(P0.05)。GG型個體在2個群體中的體斜長最大,同一群體不同基因型間差異不顯著(P0.05);不同基因型間,灘寒群體綿羊體高大于杜泊羊,但只有AA型個體在2個群體間顯著差異(P0.05)。此外,GG型個體的杜泊羊胸寬最大,AA型的最小,這與灘寒群體相反,但均沒有顯著性差異(P0.05)。FTO基因的rs160915957位點不同基因型對綿羊其他性狀的影響差異不顯著�！窘Y論】FTO基因的rs160915957位點對杜泊及灘寒綿羊群體的體重、體斜長及胸圍等具有顯著影響。FTO基因是否是影響綿羊生長性狀的主效基因尚待進一步探討,但FTO基因的rs160915957位點多態(tài)性將為不同綿羊群體后代的體重、胸圍等性狀的選擇提供參考依據(jù)。
[Abstract]:[objective] to investigate the association between FTO gene polymorphism and growth traits of different sheep populations. [methods] the polymorphism of FTO gene in Dupo sheep and Tan cold hybrid population and its relationship with growth were detected by flight mass spectrometry. [results] the weight of AA genotype individuals at rs160915957 locus of FTO gene was significantly lower than that of GG type sheep (P 0.01) and significant P 0.05 (P 0.05), respectively. The chest circumference of GG type Dupo sheep was significantly larger than that of Tan Han sheep (P 0.05). GG type individuals had the largest body oblique length in the two populations, but there was no significant difference between different genotypes of the same population (P 0.05), and among different genotypes, the body height of Tan cold sheep was higher than that of du Bo sheep. However, only the individuals of AA type had significant difference between two populations (P 0.05). In addition, the largest chest width of Dupo sheep in GG individuals was the smallest of AA type, which was contrary to that of cold beach population. However, there was no significant difference in the effect of different genotypes of rs160915957 loci on other traits in sheep. [conclusion] the rs160915957 loci of FTO gene have no significant effect on the body weight of Dupo and Tan Han sheep populations. The effects of body oblique length and chest circumference on whether the FTO gene is the main gene affecting the growth traits of sheep need to be further studied. However, the rs160915957 locus polymorphism of the FTO gene will be the weight of the offspring of different sheep populations. The selection of chest circumference and other traits provides reference basis.
【作者單位】： 寧夏大學農學院動物科學系;
【基金】：寧夏自然科學基金(NZ15030)
【分類號】：S826

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