本文選題：核磁共振成像　切入點(diǎn)：雌性仔豬　出處：《東北農(nóng)業(yè)大學(xué)學(xué)報(bào)》2017年05期

【摘要】：為研究母豬腦海馬死亡后變化情況,試驗(yàn)以同一遺傳背景(杜×長(zhǎng)×大)、體重及出生日齡相近的健康雌性仔豬作研究對(duì)象,采用核磁共振成像檢測(cè)及光鏡技術(shù),檢測(cè)母豬麻醉狀態(tài)與死后10 min、1、2、3、6和10 h時(shí)段左側(cè)、右側(cè)海馬體積,觀察兩側(cè)海馬齒狀回區(qū)顆粒細(xì)胞形態(tài),建立母豬死后海馬形態(tài)學(xué)變化模型,為長(zhǎng)期處于應(yīng)激狀態(tài)下妊娠母豬心理疾病的核磁共振診斷提供理論依據(jù)。核磁檢測(cè)結(jié)果表明,仔豬死亡10 h內(nèi),與活體對(duì)照組海馬體積比較,左側(cè)海馬體積無(wú)顯著變化(P=0.901);右側(cè)及總海馬體積在死亡3 h內(nèi)無(wú)顯著性變化(右側(cè)P=0.078;總P=0.104),但從死亡6 h開(kāi)始顯著變小(右側(cè)P0.01;總P0.05);光鏡觀察表明,仔豬死亡3 h內(nèi),左側(cè)及右側(cè)海馬齒狀回區(qū)顆粒細(xì)胞形態(tài)與活體對(duì)照組相比,均未發(fā)生嚴(yán)重?fù)p害。死亡3 h內(nèi),仔豬腦海馬組織無(wú)顯著生理變化。
[Abstract]:In order to study the changes of female piglets with the same genetic background (Tu 脳 Chang 脳 Da Pao, similar body weight and birth age) after death, nuclear magnetic resonance imaging (MRI) and light microscopy were used to study the changes of female piglets after death in sows. The left and right hippocampal volumes of sows were measured in anaesthesia state and postmortem interval of 10 min, 1min, 2h and 3h after death. The morphology of granulosa cells in the dentate gyrus of both sides of the sea horse was observed, and the model of morphological changes of hippocampus in sows after death was established. The results showed that the hippocampal volume of piglets within 10 hours of death was compared with that of the control group. There was no significant change in left hippocampal volume (P0. 901), but there was no significant change in right and total hippocampal volumes within 3 h of death (right P0. 078; total P0. 104, but significantly smaller from 6 h after death (right P0. 01; total P0. 05). Light microscopic observations showed that piglets died within 3 h. The morphology of granulosa cells in the dentate gyrus of left and right sea horses was not seriously damaged as compared with the control group, but there was no significant physiological change in the brain and horse tissues of piglets within 3 hours of death.
【作者單位】： 東北農(nóng)業(yè)大學(xué)動(dòng)物科學(xué)技術(shù)學(xué)院;東北農(nóng)業(yè)大學(xué)生命科學(xué)學(xué)院;東北農(nóng)業(yè)大學(xué)動(dòng)物醫(yī)學(xué)學(xué)院;哈爾濱工業(yè)大學(xué)校醫(yī)院;
【基金】：國(guó)家自然科學(xué)基金面上項(xiàng)目(31472131/C170109)
【分類號(hào)】：S858.28

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