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睪酮誘導(dǎo)骨髓巨噬細(xì)胞凋亡并增加杜氏利什曼原蟲對巨噬細(xì)胞的侵襲力

發(fā)布時間:2021-02-07 07:43
  Sexual dimorphism in the immune systems of females and males is well established. The sex-dependent differences between female and male normal and autoimmune responses is generally attributed to the influence of estrogens and androgens even though limited information has been reported on the specific mechanisms of steroids on immune cells. In general terms females have a greater resistance to various bacterial and viral infections than males with their other enhanced immune capabilities might co... 

【文章來源】:山西醫(yī)科大學(xué)山西省

【文章頁數(shù)】:59 頁

【學(xué)位級別】:碩士

【文章目錄】:
Abbreviations
Abstract
Introduction
    1 Effects of sex hormones on the immune response
    2 Sex hormones and macrophage functions
    3 Steroid and apoptosis
    4 Interactions between L.D and macrophage
    5 Questions
Materials and methods
Results
    1 BMMs deprived of M-CSF die through an apoptotic way
    2 Effect of testosterone on apoptosis of BMMs
    3 Effect of cyproterone on Te-induced apoptosis of BMMs
    4 Effects of sex hormones on L.D infection of Ana-Ⅰ
Discussions
Conclusions
References
Acknowledgements



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