本文選題：心中靜脈 + 豬心　； 參考：《中國醫(yī)科大學(xué)》2005年碩士論文

【摘要】：冠狀動(dòng)脈搭橋術(shù)(conventional CABG)雖然已廣為接受,但仍面臨著一些難題有待于解決。其中之一便是:對(duì)彌漫性血管病變遠(yuǎn)端通暢不良者無法施行CABG。這類患者占搭橋手術(shù)候選者的12%～15%,甚至更多。針對(duì)彌漫性血管病變遠(yuǎn)端通暢不良者施行選擇性逆向冠狀靜脈搭橋(selective retrograde coronary venous bypass,SRCVB)的研究,會(huì)為給這些患者帶來好處。 鑒于此,本研究擬就冠狀靜脈逆灌程度及臨床療效方面探討SRCVB。 目的 1 尋找選擇性逆向冠狀靜脈搭橋營養(yǎng)心肌的解剖學(xué)證據(jù),從而佐證選擇性逆向冠狀靜脈搭橋(SRCVB)的有效性。 2 通過對(duì)SRCVB術(shù)式病例手術(shù)前后對(duì)照分析、OPCABG的病例和同期行SRCVB的病例術(shù)后早期心肌酶、肌鈣蛋白水平的比較,進(jìn)一步探討SRCVB術(shù)式的臨床應(yīng)用價(jià)值。 方法 1 基礎(chǔ)實(shí)驗(yàn) 取完整的離體新鮮家豬心臟5個(gè),用25℃生理鹽水漂凈并取出房室腔內(nèi)血栓塊,從右心房側(cè)剪開冠狀靜脈竇,用5號(hào)頭皮針剪去針頭后的較柔軟硅膠管,輕柔地沿心中靜脈插入2.0～2.5cm,用1號(hào)絲線于距膠管尖端1.0～1.5cm處膠管上縫扎后室間溝內(nèi)走行的動(dòng)靜脈1～2道,防止心中靜脈回流,并縫閉后降支動(dòng)脈以模擬其閉塞。先用肝素鹽水(500ml生理鹽水加
[Abstract]:Although conventional CABG has been widely accepted, it still faces some problems to be solved. One of them was that CABGs could not be performed in patients with diffuse vascular lesions with poor distal patency. These patients account for 12 or more of the bypass surgery candidates. The study of selective retrograde coronary venous Bypass-SRCVBs for patients with diffuse vascular disease with poor distal patency may be beneficial to these patients. In view of this, this study intends to explore the degree of coronary vein reverse perfusion and clinical efficacy of SRCVB. Purpose 1 to search for anatomical evidence of selective reverse coronary vein bypass graft (SRCVB) in order to prove the validity of SRCVB (selective reverse coronary vein bypass graft). 2The clinical application value of SRCVB was further discussed by comparing the levels of cardiac enzymes and troponin in patients with SRCVB before and after operation compared with those who underwent SRCVB at the same time. Method 1 basic experiment Five isolated fresh domestic pig hearts were taken out and treated with normal saline at 25 鈩，

本文編號(hào)：1942937