發(fā)布時間：2018-12-26 19:20

【摘要】：大腦海馬區(qū)是幫助人類處理長期學習與記憶主要區(qū)域,在醫(yī)學上海馬區(qū)是大腦皮質的一個內褶區(qū),在側腦室底部繞脈絡膜裂形成一弓形隆起并由兩個扇形部分所組成,兩者合稱海馬結構。研究發(fā)現(xiàn),大多數(shù)腦部疾病的發(fā)生都跟海馬神經(jīng)元細胞息息相關,近年來,通過體外模擬腦部海馬區(qū)神經(jīng)元細胞的內環(huán)境,從體外細胞水平對腦部相關疾病的研究提供了一個新的領域。本文將通過搜集國內外近幾年對海馬神經(jīng)元細胞的分離、提取、接種、純化、鑒定等科研資料,論述海馬神經(jīng)元細胞的培養(yǎng)技術,為腦部相關疾病的研究提供相關理論技術指導。
[Abstract]:The hippocampal area of the brain is a major area that helps humans to process long-term learning and memory. In the medical Shanghai Ma area, it is an inner fold area of the cerebral cortex, forming an arcuate bulge around the choroidal fissure at the base of the lateral ventricle and consisting of two fan-shaped parts. Both are called hippocampal formation. It has been found that most brain diseases are closely related to hippocampal neurons. In recent years, we have simulated the inner environment of hippocampal neurons in vitro. The study of brain-related diseases at the cell level in vitro provides a new field. In this paper, the culture technology of hippocampal neuron cells is discussed by collecting the scientific research data such as isolation, extraction, inoculation, purification and identification of hippocampal neuron cells in recent years. To provide theoretical and technical guidance for the study of brain related diseases.
【作者單位】： 南京中醫(yī)藥大學第一臨床醫(yī)學院;廣西中醫(yī)藥大學藥學院;
【基金】：“十一五”國家科技支撐計劃中醫(yī)藥標準規(guī)范技術體系研究項目(2006BAI21 B03一10) 江蘇高校優(yōu)勢學科建設工程資助項目[PAPD]
【分類號】：R338

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