發(fā)布時間：2018-11-01 10:38

【摘要】：目的:從神經(jīng)內(nèi)分泌免疫網(wǎng)絡(luò)(NEI)角度研究脾虛痰濁證巴馬小型豬腦腸肽和神經(jīng)遞質(zhì)的影響。方法:將巴馬小型豬隨機分為正常組和模型組,施以每日沖刺跑步訓(xùn)練聯(lián)合高脂單籠飼養(yǎng)干預(yù),建立小豬脾虛痰濁證模型。應(yīng)用酶聯(lián)免疫法(Elisa)測定血清中皮質(zhì)醇(COR)、血管緊張素Ⅱ(AngⅡ)、醛固酮(ALD)、5-羥色胺(5-HT)、胰高血糖素樣肽-1(GLP-1)、乙酰膽堿(Ach)和去甲腎上腺素(NE)水平。結(jié)果:與正常組比較,模型組小型豬腦腸肽、神經(jīng)遞質(zhì)水平發(fā)生差異性變化。結(jié)論:脾虛痰濁證模型神經(jīng)內(nèi)分泌免疫網(wǎng)絡(luò)中腦腸肽、神經(jīng)遞質(zhì)失常,提示NEI是客觀存在的。某一環(huán)節(jié)的失衡可能是出現(xiàn)脾虛痰濁證的病理機制之一。
[Abstract]:Aim: to study the effects of neuroendocrine and immune network (NEI) on intestinal peptides and neurotransmitters in small pig brain of spleen deficiency and phlegm turbid syndrome. Methods: Bama miniature pigs were randomly divided into normal group and model group. The model of spleen deficiency and phlegm turbid syndrome was established by daily sprint training combined with high fat single cage feeding intervention. Serum cortisol (COR), angiotensin 鈪，

本文編號：2303662