【摘要】：目的為探究ToxoDB#17型弓形蟲對昆明小鼠的致病特點。方法分別選擇1個,1個,101個,102個,103個,104個,105個,106個ToxoDB#17型弓形蟲卵囊灌胃小鼠,觀察小鼠的臨床癥狀,采用改良凝集試驗、HE和IHC方法研究弓形蟲的感染率,小鼠生存率及其大腦內(nèi)的包囊數(shù)量。結果≥104個卵囊組小鼠在攻蟲后出現(xiàn)一過性的精神沉郁,弓背,被毛逆立現(xiàn)象,其余組精神狀態(tài)正常;≥102個卵囊可引起小鼠100%感染,感染小鼠的成囊率為2.38%(1/42),感染小鼠生存率為85.71%(36/42),存活時間≥360DPI。結論 ToxoDB#17型弓形蟲對昆明小鼠的致病力弱,包囊形成率低。
[Abstract]:Objective to study the pathogenic characteristics of ToxoDB#17 Toxoplasma gondii on Kunming mice. Methods 1, 1, 101, 102, 103, 104, 105, 106 ToxoDB#17 type Toxoplasma gondii oocysts were perfused into the stomach, and the clinical symptoms of the mice were observed. The infection rate of Toxoplasma gondii was studied by modified agglutination test (HE) and IHC. Survival rate of mice and the number of cysts in the brain. Results the mice of 鈮，

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