干細胞實現汗腺再生的機制分析
發(fā)布時間:2018-04-04 13:42
本文選題:皮膚附屬器官 切入點:同種異體皮 出處:《感染、炎癥、修復》2016年03期
【摘要】:正汗腺是重要的皮膚附屬器官,它主要通過汗液排泄調節(jié)機體的體溫,參與物質代謝并維持體液平衡。汗腺發(fā)育是一個復雜的過程,汗腺一旦被破壞則不能再生。世界上每年有數百萬的燒傷患者,其中大面積深度燒傷患者,損傷深至真皮深層或皮膚全層,此時創(chuàng)面的汗腺組織損傷無法修復,嚴重影響患者的排汗功能和生活質量[1]。然而常見的同種異體皮覆蓋創(chuàng)面的治療并沒有涉及到汗腺功能的修復,患者無法排汗的痛苦沒有得到解決。汗腺移植的研究為大面積深
[Abstract]:Positive sweat gland is an important subsidiary organ of skin. It regulates body temperature through sweat excretion, participates in substance metabolism and maintains humoral balance.Sweat gland development is a complex process, sweat glands once destroyed can not regenerate.There are millions of burn patients in the world every year, of which a large area of deep burn patients, the damage to the deep dermis or the whole skin layer, at this time, the wound sweat gland tissue damage can not be repaired, seriously affect the sweating function of patients and quality of life [1].However, the treatment of common allogeneic skin covering wounds does not involve the repair of sweat gland function, and the patient's pain of not being able to perspire has not been resolved.The study of sweat gland transplantation is deep in large area
【作者單位】: 解放軍總醫(yī)院基礎醫(yī)學研究所;解放軍總醫(yī)院第一附屬醫(yī)院全軍創(chuàng)傷修復與組織再生重點實驗室;
【基金】:國家自然科學基金資助項目(81571905,81171798,81421064,81230041) 北京市自然科學基金資助項目(7142124) 國家973計劃資助項目(2012CB518105)
【分類號】:R329.2
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本文編號:1710195
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