發(fā)布時間：2018-03-30 10:51

  本文選題：無水乙醇　切入點：宮腔注射　出處：《中國比較醫(yī)學(xué)雜志》2017年05期

【摘要】：目的探討宮腔內(nèi)注射無水乙醇對小鼠動情周期的影響。方法利用陰道脫落細(xì)胞染色法選擇動情期規(guī)律的小鼠20只,宮腔注射無水乙醇,術(shù)后第一個動情周期內(nèi)每日測定其動情周期,隨機擇10只在第二個動情周期每2 h測一次,觀察動情周期的改變程度。結(jié)果實驗小鼠宮腔注射無水乙醇后動情周期整體發(fā)生大幅度延長,且動情期、動情前期等各期時間均發(fā)生了不同程度的紊亂。結(jié)論本實驗通過觀測無水乙醇損傷子宮后小鼠動情周期發(fā)生紊亂的現(xiàn)象,為臨床無水乙醇的使用提供一定的實驗基礎(chǔ)。
[Abstract]:Objective to investigate the effect of intrauterine injection of anhydrous ethanol on estrous cycle in mice. Methods 20 mice with regular estrus period were selected by vaginal exfoliated cell staining and anhydrous ethanol was injected into uterine cavity. The estrus cycle was measured daily in the first estrus cycle after operation, and 10 were measured every 2 hours in the second estrus cycle. Results after injection of anhydrous alcohol into the uterus, the whole estrus cycle of mice was significantly prolonged, and the estrus period was also observed. Conclusion the disorder of estrus cycle in mice after anhydrous alcohol injury was observed in order to provide some experimental basis for clinical use of anhydrous ethanol.
【作者單位】： 山西醫(yī)科大學(xué)實驗動物中心實驗動物與人類疾病動物模型山西省重點實驗室;
【基金】：山西省實驗動物資源共享服務(wù)平臺建設(shè)(201605D121019) 山西省重點實驗室建設(shè)項目(2015012001-09)
【分類號】：R-332
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本文編號：1685600