本文選題：組織工程　切入點(diǎn)：模型　出處：《中國(guó)組織工程研究》2017年12期

【摘要】：背景:兔腰椎形態(tài)結(jié)構(gòu)特點(diǎn)對(duì)腰椎動(dòng)物實(shí)驗(yàn)研究起著重要的作用,但目前缺少兔腰椎形態(tài)結(jié)構(gòu)相關(guān)的研究。目的:構(gòu)建兔腰椎三維圖像模型,觀察其腰椎的形態(tài)結(jié)構(gòu)特點(diǎn),為腰椎動(dòng)物實(shí)驗(yàn)研究提供解剖形態(tài)學(xué)依據(jù)。方法:用西門子64排螺旋CT掃描20只新西蘭大白兔,獲得140節(jié)腰椎掃描資料,構(gòu)建兔腰椎三維圖像模型,測(cè)量L_(1-7)椎體的形態(tài)學(xué)參數(shù),觀察腰椎的內(nèi)外部解剖結(jié)構(gòu)及不同節(jié)段的變化特點(diǎn)。結(jié)果與結(jié)論:(1)新西蘭大白兔腰椎各解剖形態(tài)學(xué)指標(biāo)變化:兔L_(1-7)節(jié)段椎體高度呈現(xiàn)"兩頭小中間大"趨勢(shì),在L_7節(jié)段最小,其高度僅為(1.12±0.18)cm;L1節(jié)段椎體橫徑最小,為(1.03±0.15)cm,L_(1-7)節(jié)段各椎體縱徑的節(jié)段性變化較小;L_(1-6)節(jié)段椎管橫徑和縱徑均逐漸增大,L_7節(jié)段時(shí)突然變小;椎弓寬度在L_(1-7)節(jié)段逐漸增大,但變化平穩(wěn);椎弓根高度在L_(1-5)節(jié)段平穩(wěn)變化,L_(6-7)節(jié)段開始突然變小,與其他節(jié)段相差甚大,到L_7節(jié)段時(shí)最小,僅為(0.58±0.11)cm;棘突寬度和長(zhǎng)度在L_(1-6)節(jié)段平穩(wěn)增大,在L_7節(jié)段變小;橫突長(zhǎng)度在L_(1-3)節(jié)段逐漸增大,L_(3-6)節(jié)段較平穩(wěn),L_(6-7)節(jié)段顯著變小;橫突夾角在L_(1-6)節(jié)段差異度小,但在L_7節(jié)段顯著增大,為(58±2)°。(2)結(jié)果證實(shí):新西蘭大白兔腰椎形態(tài)學(xué)測(cè)量可以觀察到腰椎的內(nèi)外部解剖結(jié)構(gòu)及不同節(jié)段的形態(tài)變化特點(diǎn),為腰椎動(dòng)物實(shí)驗(yàn)研究提供詳細(xì)的解剖形態(tài)學(xué)參數(shù)資料。
[Abstract]:Background: the morphological and structural characteristics of the rabbit lumbar vertebrae play an important role in the experimental study of the lumbar vertebrae, but there is no related research on the morphology and structure of the rabbit lumbar vertebrae at present. Objective: to establish a three-dimensional model of the rabbit lumbar vertebrae and observe the morphological and structural characteristics of the lumbar vertebrae. Methods: twenty New Zealand white rabbits were scanned with Siemens 64-slice spiral CT, and 140 lumbar vertebrae scanning data were obtained. A three-dimensional model of lumbar vertebrae was constructed, and the morphological parameters of LSP 1-7) vertebrae were measured. Results and conclusion the morphological changes of the lumbar vertebrae of New Zealand white rabbits showed that the height of the lumbar vertebrae in the L1-7) segment showed a tendency of "two small middle big" and the smallest in the L7 segment, and the changes of the lumbar vertebrae and internal and external anatomical structure of the lumbar vertebrae and different segments of the lumbar vertebrae were observed. Its height was only 1.12 鹵0.18 cm ~ (-1) cm ~ (-1) cm ~ (-1) cm ~ (-1) L ~ (-1) and 1.03 鹵0.15 cm ~ (-1) cm ~ (-1) L ~ (-1). The changes of the transverse diameter and longitudinal diameter of the vertebrae were smaller than those of the L1 ~ (6) segment. The transverse diameter and longitudinal diameter of the L7 segment increased gradually, and the width of the pedicle increased gradually in the L1-7) segment, but the change was stable. The length and width of spinous process increased stably in Lstructure 1-6) segment and became smaller in L7 segment and smaller in L7 segment, and the width and length of spinous process increased steadily in Lstructure 1-6 segment and became smaller in L7 segment. The length of the transverse process gradually increased in the section of LSP _ 1-3) and the section of LSP _ 3-6) became significantly smaller than that of the section of L _ S _ I _ 6), and the angle of the transverse process became smaller in the segment of LSP _ (1-6), but increased significantly in the section of L7. The results showed that the internal and external anatomical structure of lumbar vertebrae and the morphological characteristics of different segments could be observed by morphological measurement of lumbar vertebrae in New Zealand white rabbits, which provided detailed anatomical morphological data for experimental study of lumbar vertebrae.
【作者單位】： 廣西醫(yī)科大學(xué)第四附屬醫(yī)院-柳州市工人醫(yī)院骨科;湖南省永州市中心醫(yī)院骨科;
【基金】：廣西區(qū)自然科學(xué)基金(2010GXNSFA013257)~~
【分類號(hào)】：R-332;R681.5

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