本文選題：TNFAIP　切入點(diǎn)：分子結(jié)構(gòu)　出處：《重慶醫(yī)學(xué)》2017年12期 　論文類型：期刊論文

【摘要】：正人TNF-α誘導(dǎo)蛋白1(TNFAIP1)又名B12和hBACURD2,是第一個被鑒定出的TNF-α誘導(dǎo)產(chǎn)生的蛋白,屬于hBACURD家族和PDIP1家族成員。人TNFAIP1基因首次(1992年)在TNF-α刺激、環(huán)己酰亞胺(Cycloheximide)處理的人臍靜脈內(nèi)皮細(xì)胞(HUVE)中克隆得到。人TNFAIP1基因是高度保守的單拷貝基因,定位于人染色體17q22-q23,而小鼠TNFAIP1基因采用YAC載體在鼠11號染色體克隆得到。近
[Abstract]:Is human TNF- alpha induced protein 1 (TNFAIP1) also known as B12 and hBACURD2, is the first identified TNF- alpha induced protein, are members of the hBACURD family and PDIP1 family. TNFAIP1 gene for the first time (1992) in the stimulation of TNF- alpha, cycloheximide (Cycloheximide) treated human umbilical vein endothelial cells (HUVE) was cloned. TNFAIP1 gene is a single copy gene, located on human chromosome 17q22-q23 and YAC vectors in mouse chromosome 11 by cloning of mouse TNFAIP1 gene.

【作者單位】： 廣東醫(yī)科大學(xué)東莞科研中心/廣東省醫(yī)學(xué)分子診斷重點(diǎn)實(shí)驗(yàn)室;
【基金】：國家自然科學(xué)基金資助項(xiàng)目(81500007,81272434)
【分類號】：R363
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本文編號：1575896