本文選題：大鼠　切入點(diǎn)：腹壁撤退反射實(shí)驗(yàn)(AWR)　出處：《中國(guó)比較醫(yī)學(xué)雜志》2017年08期 　論文類(lèi)型：期刊論文

【摘要】：目的為腹壁撤退反射實(shí)驗(yàn)優(yōu)選出恰當(dāng)?shù)闹苽錃饽业牟牧�。方法分別通過(guò)數(shù)顯游標(biāo)卡尺及X光圖像對(duì)不同氣囊在不同壓力值下的直徑進(jìn)行測(cè)量;并采用3分疼痛閾值作為判斷標(biāo)準(zhǔn),測(cè)試不同氣囊對(duì)大鼠造成明顯內(nèi)臟疼痛時(shí)所對(duì)應(yīng)的壓力值。結(jié)果圓形乳膠氣球的直徑隨壓力值增加變化均勻和緩,并且可以滿足實(shí)驗(yàn)中常用的壓力范圍(20~80 mm Hg),其對(duì)大鼠造成內(nèi)臟疼痛的閾值在傷害性刺激值附近,不會(huì)對(duì)大鼠腸道造成不可逆的損傷。結(jié)論腹壁撤退反射實(shí)驗(yàn)中使用圓形乳膠氣球制備氣囊較為理想。
[Abstract]:Objective to select a suitable material for abdominal withdrawal reflex experiment. Methods the diameters of different airbags under different pressure values were measured by digital display calipers and X-ray images. The three points pain threshold was used as the criterion to measure the pressure value when different airbags caused obvious visceral pain in rats. Results the diameter of circular latex balloon changed evenly and slowly with the increase of pressure. And it can satisfy the pressure range of 20 ~ 80mm Hg, the threshold of visceral pain in rats is near the nociceptive stimulation value. There is no irreversible damage to the intestine of rats. Conclusion in the experiment of abdominal wall withdrawal reflex, it is ideal to use circular latex balloon to prepare airbag.
【作者單位】： 成都中醫(yī)藥大學(xué)針灸推拿學(xué)院;
【基金】：國(guó)家自然科學(xué)基金資助項(xiàng)目(81503665) 成都中醫(yī)藥大學(xué)�；�(ZRQN1538)
【分類(lèi)號(hào)】：R-332;R57
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本文編號(hào)：1568540