NLR、PLR和CRP在小兒肺炎中的臨床意義
發(fā)布時間：2019-01-10 11:48
【摘要】：目的:探討中性粒細(xì)胞與淋巴細(xì)胞比值(Neutrophils and lymphocytes ratio,NLR)、血小板與淋巴細(xì)胞比值(Platelets and lymphocytes ratio,PLR)及 C-反應(yīng)蛋白(C-reactiveprotein,CRP)與小兒肺炎診斷及嚴(yán)重程度的關(guān)系。方法:選擇婦幼保健院中健康兒童50例作為對照組;選擇2015年1月1日至2015年12月31日在本院兒科住院的100例肺炎患兒,分為重癥肺炎組50例,輕癥肺炎組50例。檢測健康兒童、肺炎患兒入院時的血常規(guī)和CRP值,計(jì)算中性粒細(xì)胞與淋巴細(xì)胞比值(NLR)、血小板與淋巴細(xì)胞的比值(pLR),分析NLR、PLR和CRP與肺炎的診斷及嚴(yán)重程度的關(guān)系。結(jié)果:1.對照組兒童NLR平均值為0.50±0.02,肺炎組患兒NLR平均值為2.73±0.22,兩組NLR平均值比較有統(tǒng)計(jì)學(xué)意義(P0.05),輕癥肺炎NLR平均值為1.5±0.2,重癥肺炎NLR平均值為3.96±0.40,兩組比較有統(tǒng)計(jì)學(xué)意義(P0.05)。2.對照組兒童PLR平均值為52.0±3.5,肺炎組患兒為166.0±11.5,兩組比較有統(tǒng)計(jì)學(xué)意義(P0.05),輕癥肺炎PLR平均值為151±13,重癥肺炎PLR平均值為182±13,兩組比較有統(tǒng)計(jì)學(xué)意義(P0.05)。3.對照組兒童CRP平均值為3.5±0.3mg/L,肺炎組為22.81±2.11mg/L,兩組比較有統(tǒng)計(jì)學(xué)意義(P0.05),輕癥肺炎患兒CRP平均值為15.3±1.4mg/L,重癥肺炎為30.32±2.20mg/L,兩組比較有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論:NLR、PLR和CRP可作為診斷兒童肺炎的參考指標(biāo),三種指標(biāo)可鑒別患兒肺炎嚴(yán)重程度。
[Abstract]:Objective: to investigate the relationship between the ratio of neutrophil to lymphocyte (Neutrophils and lymphocytes ratio,NLR), platelet-lymphocyte ratio (Platelets and lymphocytes ratio,PLR) and C-reactive protein (C-reactive protein) in the diagnosis and severity of pneumonia in children. Methods: 50 healthy children in MCH hospital were selected as control group, and 100 children with pneumonia were divided into severe pneumonia group (n = 50) and mild pneumonia group (n = 50) from January 1, 2015 to December 31, 2015. The blood routine and CRP were measured at admission in healthy children and children with pneumonia. The ratio of neutrophil to lymphocyte (NLR), the ratio of platelet to lymphocyte (pLR),) were calculated to analyze the relationship between NLR,PLR, CRP and the diagnosis and severity of pneumonia. Results: 1. The average value of NLR was 0.50 鹵0.02 in control group and 2.73 鹵0.22 in pneumonia group. There was significant difference in NLR between the two groups (P0.05). The mean value of NLR in mild pneumonia was 1.5 鹵0.2. The average NLR of severe pneumonia was 3.96 鹵0.40, which was statistically significant (P0.05). The average value of PLR in control group was 52.0 鹵3.5, and that in pneumonia group was 166.0 鹵11.5. There was significant difference between the two groups (P0.05). The mean PLR of mild pneumonia was 151 鹵13, and that of severe pneumonia was 182 鹵13. There was statistical significance between the two groups (P0.05). The average CRP of control group was 3.5 鹵0.3 mg / L, and that of pneumonia group was 22.81 鹵2.11 mg / L (P0.05). The mean CRP of mild pneumonia group was 15.3 鹵1.4 mg / L, respectively. Severe pneumonia was 30.32 鹵2.20 mg / L, there was significant difference between the two groups (P0.05). Conclusion: NLR,PLR and CRP can be used as reference indexes in the diagnosis of pneumonia in children.
【學(xué)位授予單位】：延邊大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R725.6
，
本文編號：2406268
[Abstract]:Objective: to investigate the relationship between the ratio of neutrophil to lymphocyte (Neutrophils and lymphocytes ratio,NLR), platelet-lymphocyte ratio (Platelets and lymphocytes ratio,PLR) and C-reactive protein (C-reactive protein) in the diagnosis and severity of pneumonia in children. Methods: 50 healthy children in MCH hospital were selected as control group, and 100 children with pneumonia were divided into severe pneumonia group (n = 50) and mild pneumonia group (n = 50) from January 1, 2015 to December 31, 2015. The blood routine and CRP were measured at admission in healthy children and children with pneumonia. The ratio of neutrophil to lymphocyte (NLR), the ratio of platelet to lymphocyte (pLR),) were calculated to analyze the relationship between NLR,PLR, CRP and the diagnosis and severity of pneumonia. Results: 1. The average value of NLR was 0.50 鹵0.02 in control group and 2.73 鹵0.22 in pneumonia group. There was significant difference in NLR between the two groups (P0.05). The mean value of NLR in mild pneumonia was 1.5 鹵0.2. The average NLR of severe pneumonia was 3.96 鹵0.40, which was statistically significant (P0.05). The average value of PLR in control group was 52.0 鹵3.5, and that in pneumonia group was 166.0 鹵11.5. There was significant difference between the two groups (P0.05). The mean PLR of mild pneumonia was 151 鹵13, and that of severe pneumonia was 182 鹵13. There was statistical significance between the two groups (P0.05). The average CRP of control group was 3.5 鹵0.3 mg / L, and that of pneumonia group was 22.81 鹵2.11 mg / L (P0.05). The mean CRP of mild pneumonia group was 15.3 鹵1.4 mg / L, respectively. Severe pneumonia was 30.32 鹵2.20 mg / L, there was significant difference between the two groups (P0.05). Conclusion: NLR,PLR and CRP can be used as reference indexes in the diagnosis of pneumonia in children.
【學(xué)位授予單位】：延邊大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R725.6
，
本文編號：2406268
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