慢性萎縮性胃炎與“血瘀”證素的初步研究
[Abstract]:Objective to study the effect of blood stasis on the development of chronic atrophic gastritis (CAG) and "blood stasis" syndrome based on syndromes theory, and to explore the relationship between them. To provide evidence-based medicine theory guidance for clinical treatment of TCM syndrome differentiation, to provide new ideas for clinical treatment of CAG. Methods from January 2016 to January 2017, 92 patients with chronic atrophic gastritis, who were admitted to the second people's Hospital affiliated to Fujian University of traditional Chinese Medicine and who met the standard of Naopai, were collected by four face-to-face consultations with the informed consent of the patients. The information form of syndromes was filled out and the data of syndromes were obtained by using syndrome differentiation software. 92 cases were divided into two groups: blood stasis group (observation group, containing blood stasis syndrome element) and non-blood stasis group (control group, without blood stasis syndrome element). The basic data of the two groups were observed and compared. The clinical data, the similarities and differences of syndromes, and the relationship between the duration of disease, the degree of sublingual varicose veins, endoscopic changes of gastric mucosa and histopathological changes were observed and analyzed. Result 1. There was no difference between the blood stasis group and the non-blood stasis group in the distribution of sex, age, endoscopic changes of gastric mucosa and pathological changes, but there were differences in the distribution of the course of disease between the blood stasis group and the non-blood stasis group. There were also differences in the distribution of the degree of sublingual varicose veins. The frequency of syndromes in 2.CAG was mainly as follows: blood stasis group: stomach (19.37%), liver (15.42%), spleen (15.42%), kidney (11.07%), blood stasis group (19.37%), liver (15.42%), spleen (15.42%), kidney (11.07%). Heart (7.51%), gallbladder (6.32%); In non-blood stasis group, stomach (30.25%), liver (19.33%), spleen (11.76%), kidney (11.76%), heart spirit (5.88%), lung (5.04%) were the main groups. There was no difference in the distribution of syndromes between the two groups. The frequency of 3.CAG syndrome syndromes from high to low were: blood stasis group (11.06%), Qi stagnation (10.95%), Yang deficiency (10.53%), Qi deficiency (10.32%). Yin deficiency (9.26%), phlegm (9.05%), dampness (8.84%), blood deficiency (6.53%), heat (5.68%), food accumulation (5.05%); Non-blood stasis group: Qi stagnation (16.74%), yang deficiency (13.49%), qi deficiency (13.49%), yin deficiency (10.70%), dampness (10.23%), phlegm (7.91%), blood deficiency (6.51%), food accumulation (6.05%). Hyperyang (5.12%). There was no difference between the two groups in the distribution of syndrome factors. 4. 4. There was a positive correlation between the severity of blood stasis and the duration of disease, the degree of sublingual varicose vein and the severity of intestinal metaplasia. Conclusion the disease location of 1.CAG is mainly stomach, spleen, liver and kidney, involving heart, gallbladder, lung, heart and spirit, and the disease is usually caused by qi stagnation, yang deficiency, qi deficiency, involving yin deficiency, dampness, phlegm, blood stasis, etc. There were correlations between blood stasis, severity of aggravation and duration of disease, degree of varicose veins under tongue, severity of intestinal metaplasia, and the influence of blood stasis on the development of CAG disease.
【學(xué)位授予單位】:福建中醫(yī)藥大學(xué)
【學(xué)位級別】:碩士
【學(xué)位授予年份】:2017
【分類號】:R259
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