發(fā)布時間：2018-04-27 20:14

  本文選題：子宮肌瘤 + 介入治療�。� 參考：《新疆醫(yī)科大學》2017年碩士論文

【摘要】：目的:探討子宮動脈栓塞術(uterine artery embolization,UAE)治療子宮肌瘤的臨床效果及其對卵巢功能的影響。方法:收集2014年9月至2016年1月在我院就診的自愿接受子宮動脈栓塞治療的子宮肌瘤患者50例,均在月經(jīng)干凈后3~7天內(nèi)采用Seldinger技術進行股動脈穿刺,雙側子宮動脈經(jīng)動脈造影證實后實施子宮動脈栓塞治療。結果:50例患者均成功實施了子宮動脈栓塞術,部分患者于術后1~3d均出現(xiàn)了不同程度地下腹痛、發(fā)熱、少量陰道流血、排液等癥狀,持續(xù)4~6d后大多數(shù)可好轉,50例患者均未出現(xiàn)嚴重并發(fā)癥。50例患者于術后3月、6月、12月分別行B超復查子宮與瘤體體積,術后隨訪患者血紅蛋白、卵泡刺激素(Follicle-stimulating hormone,FSH)及黃體生成素(Luteinizing homone,LH)水平,多個時間點的重復測量資料首先采用重復測量方差分析,兩兩比較采用配對t檢驗,結果顯示子宮與瘤體體積均縮小,隨著UAE時間延長,子宮及瘤體體積均進行性縮小,差異有統(tǒng)計學意義(P0.01);UAE術后3月、6月、12月血紅蛋白水平均較術前有了不同程度的提高,差異有統(tǒng)計學意義(P0.01);UAE術前、術后3個月、6個月、12個月LH、FSH水平均無明顯變化,UAE術前術后差異無統(tǒng)計學意義(P0.05)。結論:采用子宮動脈栓塞術治療子宮肌瘤方法簡單、創(chuàng)傷小、恢復快,并且術后對卵巢功能影響較小,是治療子宮肌瘤的一種安全有效的方法,臨床上有廣泛的應用前景。
[Abstract]:Objective: to investigate the clinical effect of uterine artery embolization (artery) in the treatment of uterine leiomyoma and its effect on ovarian function. Methods: from September 2014 to January 2016, 50 patients with uterine leiomyoma who voluntarily received uterine artery embolization were collected. The femoral artery puncture was performed by Seldinger technique within 3 days after menstruation. Uterine artery embolization was performed after bilateral uterine artery was confirmed by arteriography. Results uterine artery embolization was performed successfully in all 50 patients. Some of the patients had symptoms of lower abdominal pain, fever, vaginal bleeding and drainage at 1 and 3 days after operation. After 4 ~ 6 days, the majority of 50 patients without serious complications were examined by B-ultrasound in 3 months, 6 months and 12 months after operation. Hemoglobin was followed up after operation. The levels of Follicle-stimulating hormone (FSHH) and luteinizing homoneone (LH) in follicle stimulating hormone (FSH) and luteinizing homoneone (LH) were measured. The repeated measurement data at several time points were first analyzed by repeated measurement variance analysis, and paired t test was used to compare the results. The results showed that the volume of uterus and tumor was reduced. With the prolongation of UAE time, the volume of uterus and tumor gradually decreased, and the difference was statistically significant (P 0.01). The hemoglobin levels in 3 months, 6 months and 12 months after operation were higher than those before operation, and the difference was statistically significant. There was no significant change in the level of LHG FSH at 3 months, 6 months and 12 months after UAE. There was no significant difference between the two groups before and after UAE (P 0.05). Conclusion: uterine artery embolization is a safe and effective method for the treatment of uterine leiomyoma.
【學位授予單位】：新疆醫(yī)科大學
【學位級別】：碩士
【學位授予年份】：2017
【分類號】：R737.33

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