本文選題：早泄　切入點(diǎn)：肝腎陰虛　出處：《福建中醫(yī)藥大學(xué)》2017年碩士論文　論文類型：學(xué)位論文

【摘要】：目的:觀察加味桂精湯在延長射精潛伏時間、改善癥狀、提高患者自信心及增進(jìn)夫妻情感方面對肝腎陰虛型早泄的治療作用。方法:1.選取福建中醫(yī)藥大學(xué)附屬人民醫(yī)院男科門診30例符合肝腎陰虛型早泄納入標(biāo)準(zhǔn)的患者,均簽署知情同意書,年齡在22-55歲之間,平均年齡(36.53±7.98)歲,采用自身對照的方法進(jìn)行臨床試驗(yàn)設(shè)計。2.對納入者給予加味桂精湯口服治療,每日一劑,每劑分2次沖服,療程共4周,根據(jù)患者自身情況,服藥期間每周至少房事一次。3.根據(jù)病人復(fù)診情況,觀察四個時間點(diǎn)臨床療效,于治療前,治療后1周、2周、4周的射精潛伏時間(若一周內(nèi)只有一次性生活記錄當(dāng)次時間,若有多次取均值)、早泄診斷量表、中醫(yī)癥狀變化情況,并觀查患者服藥后反應(yīng)。結(jié)果:1.患者射精潛伏時間(IELT)變化情況:治療前患者IELT在91.03±10.44秒范圍,其最大值為106.00秒,最小值71.89秒,治療四周后在242.75±88.50秒范圍,其最大值為410.84秒,最小值為76.45秒,其中5例患者IELT較治療前無延長,其余25例均不同程度延長,最大值為307.04秒,治療前后數(shù)值比較(P0.01)有明顯差異,具有統(tǒng)計學(xué)意義,有效率83.33%;2.患者早泄診斷量表(PEDT)評分情況:治療前患者PEDT評分在13.27± 1.44范圍,其最大值為16分,最小值10分,治療四周后在5.97±3.15范圍,其最大值為15分,最小值為3分,治療前后評分改善最高達(dá)11分,根據(jù)療效評價標(biāo)準(zhǔn)5例無效,顯效25例,有效率達(dá)83.33%;3.中醫(yī)癥候評分情況:治療前中醫(yī)癥候評分在20.68±2.36分,最高24分,最低16分,治療四周后在9.73±5.41分,最高21分,最低6分,治療前后分差最低1分,最高達(dá)18分,療效評價顯效5例,有效21例,無效4例,治療前后(P0.01)有明顯差異,有效率達(dá)86.67%。4.實(shí)驗(yàn)期間失訪1例患者,另2例患者因妻子早孕無法房事脫落,后續(xù)重新收集3例補(bǔ)齊。30例患者除1例訴服藥期間偶有胃脘不適、大便偏稀外,余患者未出現(xiàn)明顯不良反應(yīng)。結(jié)論:加味桂精湯對于肝腎陰虛型早泄患者有較好的臨床療效,且安全可靠,其不僅延長了患者射精潛伏時間,增強(qiáng)患者自信心,促進(jìn)夫妻生活和諧,更重要的是改善患者身體狀況,增強(qiáng)體質(zhì),多角度、全方位地達(dá)到治療目的。
[Abstract]:Objective: to observe the effect of Jiawei Gui Jing decoction on prolonging ejaculation latency and improving symptoms. Methods 1. 30 patients with premature ejaculation of liver-kidney yin deficiency type were selected from the department of andrology of the people's Hospital affiliated to Fujian University of traditional Chinese Medicine, which met the criteria for the inclusion of premature ejaculation of liver and kidney yin deficiency type. All of them signed informed consent, aged between 22 and 55 years, with an average age of 36.53 鹵7.98 years. The clinical trial design was carried out by self-control method .2.The patients were given oral treatment of Jiawei Gui Jing decoction once a day, each dose was taken twice for 4 weeks. According to the patient's own condition, at least once a week during the period of taking medicine. According to the patient's return visit, observe the clinical curative effect at four time points, before the treatment, The ejaculation latency time of 1 week, 2 weeks and 4 weeks after treatment (if there is only one life record time in one week, if there are multiple mean values, the diagnosis scale of premature ejaculation, the changes of TCM symptoms, etc.). The changes of ejaculation latency time (IELTT): before treatment, the IELT of patients was in the range of 91.03 鹵10.44 seconds, the maximum value was 106.00 seconds, the minimum value was 71.89 seconds, and after four weeks treatment, it was in the range of 242.75 鹵88.50 seconds, and the maximum value was 410.84 seconds. The minimum value was 76.45 seconds. The IELT of 5 patients was no longer than that of before treatment, while the other 25 patients had a different degree of prolongation, the maximum value was 307.04 seconds. There was significant difference in the values before and after treatment (P 0.01). The effective rate was 83.33 and 2.The score of PEDTs of patients with premature ejaculation was 13.27 鹵1.44 before treatment, the maximum value was 16 points, the minimum value was 10 points, the maximum value was 5.97 鹵3.15 after four weeks treatment, the maximum value was 15 points, the minimum value was 3 points. Before and after treatment, the highest score was 11 points, according to the evaluation criteria of curative effect, 5 cases were ineffective, 25 cases had remarkable effect, and the effective rate was 83.33 and 3.The TCM symptom score was 20.68 鹵2.36 points before treatment, the highest score was 24 points, and the lowest was 16 points. After four weeks of treatment, the scores were 9.73 鹵5.41, the highest was 21, the lowest was 6, the difference before and after treatment was the lowest and the highest was 18. There were significant differences in the evaluation of curative effect in 5 cases, effective in 21 cases, ineffective in 4 cases, and before and after treatment (P 0.01). The effective rate was up to 86.67.4.One patient was not interviewed during the experiment, the other two patients were unable to have sex because of their wife's early pregnancy. In the follow-up, 3 cases were collected again. 30 cases were collected again, except for one case who complained of epigastric discomfort and dilute stool during the period of taking medicine. Conclusion: Jiawei Gui Jing decoction has good clinical effect on premature ejaculation of liver and kidney yin deficiency type, and it is safe and reliable. It not only prolongs the latent time of ejaculation, but also enhances the self-confidence of the patients. To promote the harmonious life of husband and wife, it is more important to improve the patients' physical condition, strengthen their physique, and achieve the purpose of treatment in all directions.
【學(xué)位授予單位】：福建中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R277.5

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