本文關鍵詞： 甲狀腺結節(jié) 患病率 影響因素　出處：《新疆醫(yī)科大學》2017年碩士論文　論文類型：學位論文

【摘要】：目的:探討新疆烏魯木齊市天山區(qū)維吾爾族甲狀腺結節(jié)的患病率,并探究其影響因素。方法:應用整群隨機抽樣方式,在2015年9-12月期間內選取20~80歲的烏魯木齊市天山區(qū)居民為研究對象。對研究對象分發(fā)流行病學調查表,調查基本情況、甲狀腺病史,家族史,飲食習慣和生活習慣等方面的情況,檢查并測量身高、體重、血壓、腰圍,計算得出體重指數(shù)(BMI);收集空腹靜脈血及中段晨尿,測定血糖、糖化血紅蛋白、血脂、尿酸、尿碘等;應用甲狀腺超聲來確診甲狀腺結節(jié)。使用單因素及多因素Logistic回歸分析來得出甲狀腺結節(jié)的影響因素。結果:其中1500例調查對象中1268人完成調查,實際調查率為84.53%。天山區(qū)維吾爾族總人群中患病率為27.21%(345/1268),男性為20.49%(118/576),女性為32.80%(227/692)。女性高于男性,差異有統(tǒng)計學意義(X2=24.080,P0.01)。18~29、30~39、40~49、50~59、60~80歲甲狀腺結節(jié)患病率分別為14.55%(55/378)、16.07%(45/280)、29.93%(88/294)、45.15%(93/206)、58.18%(64/110),甲狀腺結節(jié)患病率隨著年齡的增長,隨之升高(X趨勢2=126.591,P0.01)。單因素Logistic回歸分析結果顯示:性別、年齡、吸煙史、輕度進食鹽習慣、BMI為24.0~27.9kg/m2和≥28.0 kg/m2、腰圍、空腹血糖(FPG)、口服葡萄糖耐量試驗(OGTT)-2 h血糖、糖化血紅蛋白、收縮壓、舒張壓、低密度脂蛋白、甘油三酯、總膽固醇、促甲狀腺激素(TSH)4.20 mU/L、甲狀腺過氧化物酶抗體(TPOAb)、甲狀腺球蛋白抗體(TGAb)、糖尿病、高血壓、血脂異常、甲狀腺功能減退、甲狀腺腫是甲狀腺結節(jié)的影響因素(P0.05)。多因素Logistic回歸分析結果顯示:年齡、性別和收縮壓為甲狀腺結節(jié)的獨立危險因素(P0.05)。結論:新疆烏魯木齊市天山區(qū)維吾爾族甲狀腺結節(jié)患病率較高,影響因素較多,應做到早期預防、診斷及治療。
[Abstract]:Objective: to investigate the prevalence of thyroid nodule in Uygur nationality in Tianshan District of Urumqi, Xinjiang, and to explore its influencing factors. Methods: cluster random sampling was used. During the period from September to December in 2015, the residents of Tianshan District, aged 20 or 80 years old, were selected as the subjects of the study. The epidemiological questionnaire was distributed to the subjects to investigate the basic situation, the history of thyroid diseases, family history, diet habits and habits of life and so on. Height, weight, blood pressure, waist circumference were measured, body mass index (BMI) was calculated, fasting venous blood and midmorning urine were collected, blood glucose, glycosylated hemoglobin, blood lipids, uric acid, urine iodine were measured. Univariate and multivariate Logistic regression analysis was used to determine the influencing factors of thyroid nodules. The actual rate of investigation is 84.53.The prevalence rate of thyroid nodules in the Uygur population in Tianshan District is 27.2145% 1268%, 20.499,118,576% for men, 32.80% 2227% 692% for women. The difference is statistically significant. The difference is statistically significant. The results of univariate Logistic regression analysis showed that: sex, age, smoking history, mild salt intake habit were 24.0 ~ 27.9 kg / m ~ 2 and 鈮，

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