新疆中青年缺血性卒中腦血管狹窄相關(guān)因素的研究
本文關(guān)鍵詞:新疆中青年缺血性卒中腦血管狹窄相關(guān)因素的研究 出處:《新疆醫(yī)科大學(xué)》2017年碩士論文 論文類型:學(xué)位論文
更多相關(guān)文章: 中青年 缺血性卒中 腦血管狹窄 維吾爾族 漢族
【摘要】:目的:探討中青年缺血性卒中腦血管狹窄的相關(guān)因素,及維、漢中青年缺血性卒中腦血管狹窄相關(guān)因素及分布的差異性。方法:回顧性收集中青年缺血性卒中患者520例,根據(jù)DSA或頭頸部CTA檢查分為血管狹窄組256例(男176例,女80例)和無(wú)血管狹窄組264例(男200例,女64例),根據(jù)民族將血管狹窄組分為:維吾爾族組72例(男52例,女20例),漢族組184例(男124例,女60例),收集患者臨床資料,進(jìn)行比較。結(jié)果:(1)與漢族組比較,維吾爾族組前循環(huán)血管病變率顯著升高,后循環(huán)、前-后循環(huán)聯(lián)合病變率顯著降低(P0.05)。(2)兩組均以顱內(nèi)血管病變多見(jiàn),與漢族族比較,維吾爾族組顱內(nèi)血管狹窄或閉塞率明顯升高,顱外血管狹窄或閉塞率、顱內(nèi)-外聯(lián)合病變率降低(均P0.05)。(3)與漢族族比較,維吾爾族組顱外血管輕、中度狹窄的比率較高,重度狹窄、閉塞率較低(P0.05)。(4)與漢族組比較,維吾爾族組IVA、MCA、PCA血管病變率降低,ACA、BA、I-ICA病變率升高(P0.05)。(5)與漢族組比較,維吾爾族組HHcy)、BMI≥25kg/m2、高血壓發(fā)生率增高(P0.05),吸煙、飲酒比率顯著降低(P0.05)。(6)高血壓病程≥10年、血脂異?瑟(dú)立預(yù)測(cè)中青年缺血性卒中腦血管狹窄的發(fā)生。結(jié)論:中青年缺血性卒中腦血管狹窄分布及危險(xiǎn)因素有民族差異性。長(zhǎng)期高血壓、血脂異常仍是中青年缺血性卒中血管狹窄的主要因素。
[Abstract]:Objective: To explore the related factors of cerebral vascular stenosis in young and middle-aged patients with ischemic stroke, and the correlation factors and distribution differences of cerebral vascular stenosis in young and ischemic stroke in Hanzhoung and youth. Methods: a retrospective collection of young patients with ischemic stroke in 520 cases, according to the DSA or CTA in the head and neck were divided into vascular stenosis group 256 cases (male 176 cases, female 80 cases) and non vascular stenosis group 264 cases (male 200 cases, female 64 cases), according to the national vascular stenosis group was divided into: Uygur group 72 cases (male 52 cases, female 20 cases), 184 cases in the Han group (male 124 cases, female 60 cases). The clinical data were collected and compared. Results: (1) compared with the Han group, the rate of vascular lesions in the Uygur group was significantly higher than that in the Uygur group, and the rate of the posterior circulation and the anterior and posterior circulation decreased significantly (P0.05). (2) two groups were more common with intracranial vascular disease. Compared with Han nationality, the rate of intracranial vascular stenosis or occlusion in Uygur group increased significantly, and the rate of extracranial artery stenosis or occlusion and intracranial external joint lesion were reduced (P0.05). (3) compared with the Han nationality, the rate of light and moderate stenosis of the extracranial vessels in the Uygur group was higher, and the severe stenosis and occlusion rate were lower (P0.05). (4) compared with the Han group, the rate of vascular lesions of IVA, MCA and PCA in Uygur group decreased, and the rate of ACA, BA and I-ICA increased (P0.05). (5) compared with the Han Uygur group, group HHcy) and BMI more than or equal to 25kg/m2, the incidence of hypertension increased (P0.05), smoking and drinking rates decreased significantly (P0.05). (6) more than 10 years, the course of hypertension and dyslipidemia can occur young ischemic stroke independent prediction of cerebral vascular stenosis. Conclusion: there are ethnic differences in the distribution and risk factors of cerebral vascular stenosis in young and middle-aged ischemic stroke. Long term hypertension and dyslipidemia are still the main factors of vascular stenosis in young and middle-aged ischemic stroke.
【學(xué)位授予單位】:新疆醫(yī)科大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2017
【分類號(hào)】:R743.3
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