四逆湯加味聯(lián)合督脈灸治療“純陰結(jié)”便秘型腸易激綜合征臨床研究
本文關(guān)鍵詞:四逆湯加味聯(lián)合督脈灸治療“純陰結(jié)”便秘型腸易激綜合征臨床研究 出處:《福建中醫(yī)藥大學(xué)》2017年碩士論文 論文類(lèi)型:學(xué)位論文
更多相關(guān)文章: 腸易激綜合征 便秘 純陰結(jié) 四逆湯 督脈灸
【摘要】:目的:本課題著重探究臨床中應(yīng)用經(jīng)方四逆湯加味聯(lián)合督脈灸治療"純陰結(jié)"便秘型腸易激綜合征的臨床療效,驗(yàn)證經(jīng)方配合中醫(yī)外治其可行性及科學(xué)性,進(jìn)一步為中醫(yī)內(nèi)外結(jié)合治療"純陰結(jié)"便秘腸易激綜合征提供臨床理論指導(dǎo)。方法:選取符合納入標(biāo)準(zhǔn),經(jīng)排除標(biāo)準(zhǔn)篩選的患者70例,隨機(jī)分為治療組(35例),對(duì)照組(35例),治療組有1例脫落,對(duì)照組2例脫落,兩組病例均進(jìn)行調(diào)整生活起居,改善飲食結(jié)構(gòu),適當(dāng)運(yùn)動(dòng)等一般治療,在一般治療基礎(chǔ)上治療組加予四逆湯加味聯(lián)合中醫(yī)外治督脈灸治療,方中中藥飲片由龍巖市中醫(yī)院統(tǒng)一購(gòu)買(mǎi),并煎煮成200ml袋裝中藥湯劑,每次1袋,每日2次,分早晚溫服,依據(jù)患者癥狀變化和個(gè)體差異情況調(diào)整中藥飲片用量,并聯(lián)合督脈灸(患者俯臥床上,充分暴露后背,在督脈大椎穴至腰俞穴范圍鋪上一層紗布,將事先搗成泥狀的生姜平鋪于督脈上,將純艾絨沿督脈長(zhǎng)軸平鋪于姜泥上,點(diǎn)燃艾絨即可,施灸者不可離開(kāi),以防燙傷。督脈灸全程中,簡(jiǎn)便、易行。每周1次,每次1.5-2小時(shí))。對(duì)照組在一般治療基礎(chǔ)上給予乳果糖口服液(Abbott Healthcare Products B.V.生產(chǎn)),每次1OmL,口服,每天3次;兩組均治療4周為1療程,共觀察1個(gè)療程。治療結(jié)束后3個(gè)月時(shí)對(duì)兩組患者進(jìn)行回訪;觀察兩組治療前后及回訪時(shí)患者臨床癥狀體征方面的變化,比較并評(píng)價(jià)兩組的治療療效。結(jié)果:1.基線資料差異性比較:兩組患者在性別、年齡、病程、癥狀體征等方面經(jīng)統(tǒng)計(jì)學(xué)處理,無(wú)顯著性差異,具有可比性(P0.05)。2.經(jīng)過(guò)4周的治療,治療組與對(duì)照組在臨床療效改善方面差異明顯,具有統(tǒng)計(jì)學(xué)意義(P0.05);在大便干結(jié)、排便頻率癥狀改善方面兩組并無(wú)顯著差異(P0.05),在排便困難、腹痛、腹脹、四肢不溫等癥狀方面兩組均有顯著差異(P0.05),且治療組優(yōu)于對(duì)照組(P0.05);3.在遠(yuǎn)期療效方面,治療組優(yōu)于對(duì)照組,差異有統(tǒng)計(jì)學(xué)意義(P0.05);4.治療組予對(duì)照組對(duì)血、尿、糞常規(guī)+OB及肝腎功能等方面均無(wú)明顯影響。結(jié)論:經(jīng)方四逆湯加味聯(lián)合督脈灸為治療"純陰結(jié)"便秘型腸易激綜合征的有效中醫(yī)內(nèi)外治聯(lián)合方法,能顯著改善患者的臨床癥狀體征、中醫(yī)癥候,遠(yuǎn)期療效良好,無(wú)明顯不良反應(yīng)。
[Abstract]:Objective: This paper focuses on exploring the clinical curative effect of four inverse decoction combined with Du moxibustion in the treatment of "pure Yin" constipation irritable bowel syndrome clinical application of classical prescriptions in the treatment of the feasibility and scientific verification prescription combined with traditional Chinese medicine, further for TCM internal and external treatment of "pure Yin" constipation irritable bowel syndrome with clinical guidance. Methods: the criteria, 70 cases were excluded by standard screening patients, randomly divided into treatment group (35 cases) and control group (35 cases), the treatment group had 1 cases to fall off, the control group of 2 cases off, two cases were adjusted to daily life, improve diet, exercise and other general treatment on the basis of the general treatment, treatment group were treated with four inverse decoction combined with external treatment of traditional Chinese medicine Du moxibustion in Chinese herbal medicine purchasing by Longyan Hospital of Traditional Chinese Medicine, and decocted into 200ml bagged decoction, 1 bag each time, 2 times a day, morning and evening clothes, on the basis of patient symptoms and changes of amount of individual differences in adjustment of Chinese herbal medicine and, combined with Moxibustion (DU patients prone to bed, fully exposed in the back, Du Dazhui to Yaoshu range covered with a layer of gauze, will advance mashed ginger tile to Du, pure moxa long axis along the Du channel tile to ginger, ignite moxa You can not leave the moxibustion, in order to prevent scald. Du moxibustion process, simple and easy. 1 times a week, each time 1.5-2 hours). The control group was given lactulose oral liquid (Abbott Healthcare Products B.V. production) on the basis of general treatment, each time 1OmL, orally, 3 times a day. The two groups were treated for 4 weeks for 1 courses, a total of 1 courses were observed. After 3 months of treatment, two groups of patients were followed up. The clinical symptoms and signs of two groups before and after treatment were observed, and the therapeutic effects of the two groups were compared and evaluated. Results: 1. baseline data difference comparison: two groups of patients in gender, age, course of disease, symptoms and signs and other aspects of statistical processing, no significant difference, comparable (P0.05). 2. after 4 weeks of treatment, the treatment group and the control group in improving clinical curative effect difference was statistically significant (P0.05); there is no difference between the two groups was significantly improved in dry stool, defecation frequency of symptoms (P0.05), significant differences between the two groups in terms of difficult defecation, abdominal pain, abdominal distension, limbs cold and other symptoms (P0.05), and the treatment group than the control group (P0.05); 3. in the long-term curative effect, the treatment group than the control group, the difference was statistically significant (P0.05); 4. in the treatment group were given to the control group had no obvious effect on blood, urine and stool routine +OB and kidney function etc.. Conclusion: TCM prescription effective four inverse decoction combined with moxibustion for treatment of "pure Yin Du knot constipation type irritable bowel syndrome and treatment method, can significantly improve the patient's clinical symptoms, TCM syndrome, the long-term curative effect is good, no obvious adverse reaction.
【學(xué)位授予單位】:福建中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2017
【分類(lèi)號(hào)】:R259
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