本文選題：活性污泥 + 四環(huán)素�。� 參考：《環(huán)境科學學報》2017年11期

【摘要】：城市污水處理廠中抗生素抗性菌的富集和擴散對受納水體及公共衛(wèi)生安全造成嚴重的威脅.本研究從上海某城市污水處理廠活性污泥中篩選得到一株四環(huán)素抗性菌株TC-1,基于形態(tài)特征、生理生化特性和16S r DNA結果鑒定,菌株TC-1屬于節(jié)桿菌屬(Arthrobacter sp.).對節(jié)桿菌屬菌株的全基因組分析表明,菌株TC-1含有多種抗生素抗性基因,包括四環(huán)素、氯霉素、大環(huán)內(nèi)酯類和青霉素抗性基因.對比節(jié)桿菌屬抗生素抗性基因的基因簇分析表明,這些抗性基因在節(jié)桿菌屬中具有普遍存在性,表明其來源于相關菌株的遺傳而非單個菌株的偶然獲得.鑒于節(jié)桿菌屬是潛在的病原性微生物,該結論可為廢水生物處理系統(tǒng)中含抗生素抗性基因的致病微生物環(huán)境行為和風險評估提供參考.
[Abstract]:The enrichment and diffusion of antibiotic resistant bacteria in municipal wastewater treatment plants pose a serious threat to the acceptance of water and public health. A tetracycline resistant strain TC-1 was isolated from activated sludge of a municipal wastewater treatment plant in Shanghai. Based on morphological characteristics, physiological and biochemical characteristics and 16s r DNA results, the strain TC-1 belongs to Arthrobacter sp. Genomic analysis of the genus Arthrobacter showed that the strain TC-1 contained many antibiotic resistant genes, including tetracycline, chloramphenicol, macrolides and penicillin resistance genes. The gene cluster analysis of antibiotic resistance genes of Arthrobacter showed that these genes were ubiquitous in the genus Arthrobacter, indicating that these genes were derived from the inheritance of the related strains rather than from the accidental acquisition of individual strains. Since Arthrobacter is a potential pathogenic microorganism, this conclusion can be used as a reference for environmental behavior and risk assessment of pathogenic microorganisms with antibiotic resistance genes in wastewater biological treatment system.
【作者單位】： 華東理工大學資源與環(huán)境工程學院國家環(huán)境保護化工過程環(huán)境風險評價與控制重點實驗室;
【基金】：國家自然科學基金(No.41001316) 國家科技部水污染控制與治理科技重大專項(No.2014ZX07104006)~~
【分類號】：X799.3

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