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鯽魚對水中有機防曬劑的富集及代謝酶響應(yīng)

發(fā)布時間:2017-12-28 16:08

  本文關(guān)鍵詞:鯽魚對水中有機防曬劑的富集及代謝酶響應(yīng) 出處:《中國環(huán)境科學》2017年09期  論文類型:期刊論文


  更多相關(guān)文章: 鯽魚 OD-PABA 組織分布 生物富集 代謝酶


【摘要】:采用半靜態(tài)水體暴露方法研究了有機防曬劑對二甲氨基苯甲酸異辛酯(OD-PABA)在鯽魚不同組織的分布、累積及生態(tài)毒理效應(yīng).結(jié)果表明,OD-PABA在不同組織中的含量隨著水體暴露濃度的升高而持續(xù)升高,并在14或28d達到最大.不同濃度的OD-PABA在不同組織的生物富集因子(BCF)存在明顯差異,基于暴露14d和28d計算得到的BCF值,肝臟為123~186,皮膚為117~163,腎臟為90.2~147.OD-PABA對鯽魚肝臟EROD、PROD、BFCOD和GST活性都產(chǎn)生了誘導(dǎo)效應(yīng),其中EROD和GST的響應(yīng)更為顯著,最大誘導(dǎo)倍數(shù)分別為0.97和0.53倍.結(jié)果表明,水中的OD-PABA可在鯽魚體內(nèi)富集,并通過I相和II相代謝酶進行生物轉(zhuǎn)化.
[Abstract]:The semi static water of organic sunscreen to two methyl amino benzoic acid isooctyl ester (OD-PABA) method to expose the distribution, accumulation and ecotoxicological effects in different tissues of crucian carp. The results showed that the content of OD-PABA in different tissues increased with the exposure concentration and water continued to rise, and reached a maximum at 14 or 28d. The concentration of OD-PABA in different tissues of the enrichment of biological factors (BCF) have obvious difference, the exposure of 14d and 28d were calculated based on the BCF value, liver 123~186, skin 117~163, kidney 90.2~147.OD-PABA on EROD, PROD and BFCOD in liver of crucian carp and GST activity induced effect, the response of EROD and GST more obviously, the maximum induction times were 0.97 and 0.53 times. The results show that the water OD-PABA in crucian carp enrichment, and through the I phase and II phase metabolic enzyme biological transformation.
【作者單位】: 西藏農(nóng)牧學院水利土木工程學院;河海大學環(huán)境學院淺水湖泊綜合治理與資源開發(fā)教育部重點實驗室;
【基金】:西藏農(nóng)牧學院雅江學者計劃(2015XYA01) 國家自然科學基金創(chuàng)新群體項目(51769034)
【分類號】:X592
【正文快照】: 有機防曬劑(Organic UV Filters,OUVFs)是具有羰基共軛或雜環(huán)的芳香族有機化學品,具有強烈地選擇性吸收紫外線的性能.OUVFs除了作為防曬成分用于個人護理品以外,還被廣泛添加到家居產(chǎn)品、紡織品、塑料、光學產(chǎn)品、農(nóng)業(yè)化學品和涂料等產(chǎn)品中,防止紫外線照射[1].近年來,紫外線輻,

本文編號:1346482

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