本文選題：情緒調(diào)節(jié)　切入點(diǎn)：認(rèn)知重評(píng)　出處：《深圳大學(xué)》2017年碩士論文　論文類(lèi)型：學(xué)位論文

【摘要】：良好的情緒調(diào)節(jié)能力是適應(yīng)社會(huì)的重要條件,而雙相抑郁患者和抑郁障礙患者存在明顯的持續(xù)性情緒低落,在情緒的加工和調(diào)節(jié)上存在困難。已有的研究多關(guān)注于疾病的鑒別診斷和治療方面,較少關(guān)注單雙相抑郁障礙患者社會(huì)認(rèn)知方面,尤其是情緒調(diào)節(jié)能力。認(rèn)知重評(píng)作為一種使用廣泛的情緒調(diào)節(jié)策略,在眾多研究中表現(xiàn)出良好的情緒調(diào)節(jié)能力和社會(huì)適應(yīng)性,有必要對(duì)單雙相抑郁發(fā)作患者使用認(rèn)知重評(píng)的情況進(jìn)行探索。本研究采用問(wèn)卷調(diào)查對(duì)單雙相抑郁患者常用的情緒調(diào)節(jié)策略進(jìn)行比較,使用認(rèn)知重評(píng)范式對(duì)被試在主觀情緒評(píng)定和近紅外腦功能成像(Near-infrared spectroscopy,NIRS)方面的結(jié)果進(jìn)行對(duì)比,探究其能否幫助患者進(jìn)行有效的情緒調(diào)節(jié),并通過(guò)影像學(xué)方面的比較以期為兩者鑒別診斷提供神經(jīng)生理學(xué)依據(jù)。使用情緒調(diào)節(jié)量表(ERS)對(duì)19名雙相抑郁患者、25名抑郁障礙患者和22名對(duì)照組進(jìn)行測(cè)量,比較三組被試在慣用情緒調(diào)節(jié)策略上的差異。結(jié)果顯示,單雙相抑郁患者在表達(dá)抑制的使用上與對(duì)照組沒(méi)有顯著差異,但在認(rèn)知重評(píng)策略的使用上顯著少于對(duì)照組。說(shuō)明相比于正常人群,抑郁發(fā)作的患者使用認(rèn)知重評(píng)這種適應(yīng)性的情緒調(diào)節(jié)策略頻率更少。采用3×3×2的設(shè)計(jì)對(duì)被試在認(rèn)知重評(píng)任務(wù)下的行為學(xué)(主觀情緒等級(jí)評(píng)分)和NIRS數(shù)據(jù)進(jìn)行分析,其中組別為組間變量,情緒類(lèi)型和實(shí)驗(yàn)操作為組內(nèi)變量。三組被試在認(rèn)知重評(píng)條件下對(duì)負(fù)性情緒刺激的主觀評(píng)分顯著高于自然觀看時(shí),雙相組在認(rèn)知重評(píng)后的主觀評(píng)分顯著高于之前;單相組在認(rèn)知重評(píng)前后的主觀評(píng)分沒(méi)有顯著差異,但都顯著低于對(duì)照組。表明認(rèn)知重評(píng)對(duì)負(fù)性情緒有良好的調(diào)節(jié)作用,雙相患者認(rèn)知重評(píng)作用顯著。NIRS分析結(jié)果顯示,單相組在進(jìn)行認(rèn)知重評(píng)時(shí)通道6、14、16的腦活動(dòng)變化顯著,通道16上兩組患者的活動(dòng)差異顯著,通道13、17、19顯示出被試在認(rèn)知重評(píng)前后對(duì)不同的情緒類(lèi)型反應(yīng)產(chǎn)生顯著變化。認(rèn)知重評(píng)主要激活前額葉皮層的中部及右側(cè),單相抑郁患者表現(xiàn)為兩側(cè)DLPFC及右側(cè)PFC后部的激活相對(duì)減弱,BD組的右側(cè)PFC后部相對(duì)于對(duì)照組激活減弱,MDD組在認(rèn)知重評(píng)時(shí)右側(cè)DLPFC的激活比BD組減弱。
[Abstract]:Good emotion regulation ability is an important condition to adapt to the society, and bipolar depression and depressive disorder patients have obvious persistent depression, There are difficulties in emotional processing and regulation. Previous studies have focused on the differential diagnosis and treatment of the disease, and less on the social cognition of patients with bipolar depression. As a widely used emotion regulation strategy, cognitive reassessment has shown good emotion regulation ability and social adaptability in many studies. It is necessary to explore the use of cognitive reassessment in patients with bipolar depression. The results of subjective emotion assessment and Near-infrared imaging (NIRS) were compared using cognitive reassessment paradigm to explore whether they could help patients with effective emotional regulation. In order to provide neurophysiological basis for the differential diagnosis, 19 bipolar depression patients (25 patients with depression) and 22 controls were measured with emotion Regulation scale (ERS). The results showed that there was no significant difference in the use of expression inhibition between the patients with bipolar depression and the control group. But the use of cognitive reassessment strategies was significantly lower than that of the control group. Patients with depression were less likely to use the adaptive emotion regulation strategy of cognitive reassessment. The behavioral (subjective emotion rating) and NIRS data were analyzed by using 3 脳 3 脳 2 design. Among them, the group was inter-group variable, the emotional type and experimental operation were intra-group variables. The subjective scores of negative emotional stimulation in the three groups were significantly higher than those in natural viewing. The subjective scores of bipolar group were significantly higher after cognitive reevaluation than before, and the subjective scores of monophasic group before and after cognitive reevaluation were not significantly different, but were significantly lower than those of control group. The results of NIRS analysis showed that the brain activity of the monophasic group changed significantly during the cognitive reassessment, and the difference between the two groups was significant. The responses to different emotion types were significantly changed before and after cognitive reassessment. Cognitive reassessment mainly activated the middle and right of prefrontal cortex. In monophasic depression patients, the activation of bilateral DLPFC and the posterior part of right PFC was relatively weakened. The activation of the right posterior PFC of BD group was weaker than that of the control group. The activation of right DLPFC in the group of MDD was lower than that in the group BD during cognitive reassessment.
【學(xué)位授予單位】：深圳大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類(lèi)號(hào)】：B842.1

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