隨著近年來電紡納米技術(shù)的發(fā)展,含有先進特性的納米纖維的生產(chǎn)和開發(fā)認識到了潛在好處,如抗菌保護膜、創(chuàng)面繃帶、醫(yī)用防護服和其他醫(yī)療產(chǎn)品等生物醫(yī)用紡織品的應用�，F(xiàn)在,抗菌性能成為生物醫(yī)用紡織品領域的重要性能。上述醫(yī)療產(chǎn)品的例子,如果上述產(chǎn)品具有抗菌性能,那么它們的應用是非常具有標志性的�？咕镝t(yī)學紡織品的主要優(yōu)點和目的是防止各種感染和快速愈合傷口并保持生物安全性。在生物醫(yī)用紡織品的開發(fā)中,這些特殊用途的材料需要具有特殊的材料性能。包括具有良好的透氣性、良好的吸收性能、最佳的熱性能和機械性能以及良好的可紡性。材料的其他特性對醫(yī)學應用十分重要,包括具有環(huán)保、生物安全性、生物降解性、吸收性好、光滑性好、不含雜質(zhì)等特點。在紡織工業(yè)中,靜電紡絲是一種適合于制造電紡絲聚合物納米纖維、復合材料、聚合物共混物（用蒙脫土和有機改性蒙脫土等天然粘土）的技術(shù),這種技術(shù)具有可改變的極性、滲透性和與最終用途相關的直徑。靜電紡絲參數(shù)對生產(chǎn)特定用途的聚合物納米纖維起著關鍵作用。在這些關鍵參數(shù)中,最重要的是溶劑的選擇。選擇一種溶劑使聚合物溶解良好,使納米纖維紡絲均勻,主要是基于對聚合物-溶劑機理的認識。這種溶劑的選擇對控... 

【文章來源】：江南大學江蘇省 211工程院校 教育部直屬院校

【文章頁數(shù)】：122 頁

【學位級別】：博士

【文章目錄】：
Acknowledgement
Dedication
Abbreviations
Abstract
摘要
Chapter1 Literature review
    1.1 Introduction of electrospinning
        1.1.1 A historical background of electrospinning
        1.1.2 Mechanism of electrospinning process
        1.1.3 Influencing parameters for electrospinning process
        1.1.4 Fabrication of nanofibers by electrospinning for biomedical textile applications
    1.2 ATRP Technique
        1.2.1 Introduction
        1.2.2 Grafting monomer
    1.3 Poly(lactic acid)polymer
        1.3.1 Structure of PLA
        1.3.2 Properties of PLA
    1.4 Polymer/clay nanocomposites
        1.4.1 Structure and composition of montmorillonite clay
        1.4.2 Nanoclay Based Composites
        1.4.3 Polylactic acid biomedical textile application
    1.5 Antimicrobial photodynamic therapy
        1.5.1 Introduction
        1.5.2 History of photodynamic therapy
        1.5.3 Antibacterial mechanism
        1.5.4 Photosensitizers
        1.5.5 Light sources used in photodynamic therapy
    1.6 Problem Statement
    1.7 Advantages of antibacterial photodynamic therapy(PDT)over antibiotics
    1.8 Research objectives of the thesis
    References
Chapter2 Preparation and characterization of antimicrobial electrospun PLA and OMMT hybrid nano-fabrics via dip-coating
    2.1 Introduction
    2.2 Experimental section
        2.2.1 Materials
        2.2.2 Production of PLA nanofiber
        2.2.3 Synthesis of PLA/OMMT hybrid nanocomposites
        2.2.4 Preparation of Methylene blue absorbed PLA)/OMMT hybrid nanocomposites
    2.3 Characterization
    2.4 Mechanical testing
    2.5 Water absorption testing
    2.6 Antibacterial photodynamic inactivation assay
    2.7 Results and Discussion
        2.7.1 Morphology of PLA nanofiber
        2.7.2 Water absorption
        2.7.3 Mechanical testing
        2.7.4 Evaluation of antibacterial efficacy
    2.8 Summary
    References
Chapter3 Characterization of electrospun membranes fabricated via solution of PLA/organo modified MMT
    3.1 Introduction
    3.2 Experimental section
        3.2.1 Materials
        3.2.2 Instrumentation
        3.2.3 Preparation of PLA/OMMT blend solutions
        3.2.4 Electrospinning of PLA/MMT nanofibers membranes
    3.3 Result and discussion
        3.3.1 Effect of PLA solution concentration
        3.3.2 Effect of OMMT contents
        3.3.3 Fourier transform infrared(FT-IR)analysis
        3.3.4 Air permeability
    3.4 Summary
    References
Chapter4 Antimicrobial activity of2 dimethylaminoethyl methacrylate graft poly lactic acid nanofiber Membrane via Graft copolymerization
    4.1 Introduction
    4.2 Experimental section
        4.2.1 Materials
        4.2.2 Instrumentation:
        4.2.3 Fabrication of electrospun PLA solutions
        4.2.4 ATRP copolymerization technique
        4.2.5 Quaternization modification of bacterial PLA copolymer
        4.2.6 Characterization of nanofiber membrane
        4.2.7 Antibacterial studies
    4.3 Results and discussion
    4.4 Summary
    References
Chapter5 Preparation of photodynamic PLA composite nanofibers doped with MMT:a facile method for increasing antimicrobial efficiency
    5.1 Introduction
    5.2 Experimetal section
        5.2.1 Materials
        5.2.2 Electrospinning of PLA/OMMT nanofibers membranes
        5.2.3 Characterization of electrospun PLA/OMMT nanofibers membranes
        5.2.4 Mechanical performance
        5.2.5 Contact angle
        5.2.6 Thermal properties
        5.2.7 Preparation of methylene blue absorbed PLA)/OMMT composite nanofibers membranes
        5.2.8 Antibacterial photodynamic inactivation assay
    5.3 Results and discussion
        5.3.1 Structural morphology
        5.3.2 Fourier transform infrared(FTIR)spectroscopy
        5.3.3 Surface composition analysis
        5.3.4 Water absorbency
        5.3.5 Mechanical testing
        5.3.6 Thermal properties
        5.3.7 Evaluation of antibacterial efficacy
    5.4 Summary
    References
Chapter6 Conclusion and recommendations
List of Publications



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