【摘要】：目的分析某醫(yī)院1 138株金黃色葡萄球菌分離株的分布特點及耐藥狀況。方法選擇1 138株2012~2014年分離的金黃色葡萄球菌分離株。分離株主要來自痰液(360株、31.6%)、傷口分泌物(272株、23.9%)和其他分泌物株(205株、18.0%),科室主要來自燒傷科(278株、24.4%)、兒科(116株、10.2%)、耳鼻喉科(114株、10.0%)。采用紙片擴散法進行藥敏實驗,分析其耐藥情況。結(jié)果 1 138株金黃色葡萄球菌分離株中耐甲氧西林金黃色葡萄球菌(MRSA)457株(40.2%)、甲氧西林敏感金黃色葡萄球菌(MSSA)681株(59.8%)。MRSA對青霉素G、頭孢呋辛、頭孢噻肟、頭孢唑啉、苯唑西林的耐藥率均為100%,而MSSA分別為6.3%、7.6%、8.1%、0、7.3%,MRSA耐藥率高于MSSA(P均0.05)。結(jié)論院內(nèi)分離的金黃色葡萄球菌菌株中MRSA檢出率較高,且多重耐藥菌株多見。臨床醫(yī)生需根據(jù)菌株藥敏結(jié)果合理使用抗菌藥物。
[Abstract]:Objective to analyze the distribution and drug resistance of 1 138 Staphylococcus aureus isolates in a hospital. Methods 1 138 Staphylococcus aureus isolates from 2012 to 2014 were selected. The isolates were mainly from sputum (360 strains, 31.6%), wound secretions (272 strains, 23.9%) and other secretions (205 strains, 18.0%). Otorhinolaryngology (114 strains, 10.0%). The drug sensitivity test was carried out by disk diffusion method, and the drug resistance was analyzed. Results among 1 138 isolates of Staphylococcus aureus, 457 strains (40.2%) were methicillin-resistant Staphylococcus aureus and 681 (59.8%). MRSA were methicillin-sensitive Staphylococcus aureus against penicillin G and cefuroxime. The drug resistance rates of cefotaxime, cefazolin and oxacillin were 100, while MSSA were 6.3and 7.6and 8.1cm, respectively. The resistance rate of MSSA was higher than that of MSSA (P. Conclusion the detection rate of MRSA in Staphylococcus aureus strains isolated in hospital is high, and multidrug resistant strains are more common. The clinical doctor should use the antibiotics reasonably according to the drug sensitivity result of the strain.
【作者單位】： 寧夏醫(yī)科大學臨床學院;甘肅省人民醫(yī)院檢驗中心;甘肅省中醫(yī)藥大學;
【基金】：甘肅省衛(wèi)生行業(yè)科研基金資助項目(GSWST2012-04)
【分類號】：R446.5

【參考文獻】

相關(guān)期刊論文 前10條

1 張紅艷;趙鵑;丁少川;鄭良建;夏蘭;;120株耐甲氧西林金黃色葡萄球菌的臨床分布及耐藥性分析[J];中國衛(wèi)生檢驗雜志;2016年13期

2 尹丹萍;陳慶瑩;肖鵬云;張玉強;公衍文;;醫(yī)院感染病原菌分布與耐藥性研究[J];中華醫(yī)院感染學雜志;2015年23期

3 泰淑紅;王鵬;徐豪;邵艷;賈莉婷;;333株金黃色葡萄球菌引起的臨床感染類型及耐藥性分析[J];現(xiàn)代預防醫(yī)學;2015年22期

4 周龍;喬甫;黃文治;宗志勇;;血流感染耐甲氧西林金黃色葡萄球菌對患者預后的影響[J];中國感染控制雜志;2015年01期

5 王艷;周麗萍;巢國祥;吳艷濤;張小榮;;金黃色葡萄球菌MRSA分型及分子溯源研究[J];中國衛(wèi)生檢驗雜志;2014年20期

6 孟祥兆;李桂玲;陳勇;韓黎;多麗波;;臨床分離金黃色葡萄球菌的流行病學特征分析[J];中國衛(wèi)生檢驗雜志;2014年07期

7 邱玉玉;李曉霞;于愛蓮;張忠;陳國敏;史衛(wèi)峰;莊東明;趙英會;王占華;張海濤;耿希華;朱強;;醫(yī)院內(nèi)氣載耐甲氧西林金黃葡萄球菌(MRSA)耐藥性及耐藥基因分析[J];中國病原生物學雜志;2014年01期

8 劉彩林;孫自鏞;陳中舉;朱旭慧;李麗;張蓓;田磊;王斌;朱琴;汪s，

本文編號：2322435