綜合ICU患者貧血現(xiàn)況調(diào)查及原因分析
發(fā)布時間:2018-11-01 10:40
【摘要】:目的:對綜合ICU患者貧血的現(xiàn)況進行描述,了解非失血性膿毒癥患者血紅蛋白的變化過程及可能的原因。方法:收集寧夏醫(yī)科大學總醫(yī)院2015年1月1日至12月31日所有收住ICU的患者,經(jīng)排除標準篩選后,對ICU患者的血紅蛋白及標本采集失血量進行回顧性分析。記錄患者的一般資料、入院診斷、入科基礎(chǔ)血紅蛋白(Hb)數(shù)值、入ICU 24小時內(nèi)急性生理學及慢性健康評分(APACHEⅡ評分)及序貫器官衰竭估計評分(SOFA評分)、ICU期間血紅蛋白(Hb)水平、住院天數(shù)、標本采集失血量,得出入科患者貧血發(fā)生的情況,并排除顯性失血量大于50ml的患者,將患者病情按膿毒癥及非膿毒癥進行分組,分別了解其血紅蛋白的變化情況。結(jié)果:寧夏醫(yī)科大學總醫(yī)院2015年1月1日至12月31日共收治患者794例,251例患者符合納入標準。在ICU住院期間貧血發(fā)生率為58%,患者血紅蛋白平均下降2.41±4.25g/L/day。對于210例住ICU時間大于2天的患者,前2天血紅蛋白下降程度大于后續(xù)時間,前2天血紅蛋白變化為:7.8±12.2g/L/day,兩天后血紅蛋白變化為:2.3±14.1g/L/day(P0.01)。對于住院時間大于兩天的患者,后續(xù)住院時間的日均血紅蛋白下降水平與APACHE II評分及SOFA評分呈正相關(guān)(P=0.00、P=0.00)。251例入選患者入科后接受抽血次數(shù)為22.43±16.85次,平均每天采血數(shù)量為4.16±1.71管,總采血量為74.45±45.90ml,膿毒癥患者112人,平均每天采血數(shù)量為4.58±1.98管,采血總量為100.24±55.54ml,非膿毒癥患者139人,平均每天采血量為3.83±1.37管,采總血量為53.52±40.85ml。251例入選患者,除外創(chuàng)傷性失血、術(shù)中失血、消化道出血量大于50ml的患者,共57例入選,其中膿毒癥患者36例,非膿毒癥患者21例,膿毒癥患者血紅蛋白下降為2.31±2.56g/L/day,非膿毒癥患者血紅蛋白下降為0.92±2.34g/L/day(P=0.04),對于住院時間大于2天的患者,前2天膿毒癥患者血紅蛋白下降8.28±12.92g/L,非膿毒癥患者血紅蛋白下降3.86±12.09g/L(P=0.30),2天后膿毒癥患者組血紅蛋白持續(xù)下降,而非膿毒癥患者組血紅蛋白無明顯下降(9.28±11.39 VS 1.25±6.68g/L P=0.03)。結(jié)論:1、寧醫(yī)大總院ICU患者入院第二天血紅蛋白下降最顯著。2、膿毒癥患者血紅蛋白下降原因考慮與疾病本身嚴重程度及靜脈采血量有關(guān)。
[Abstract]:Objective: to describe the current status of anemia in patients with ICU and to understand the process and possible causes of hemoglobin changes in patients with non-hemorrhagic sepsis. Methods: all the patients with ICU were collected from January 1 to December 31, 2015 in Ningxia Medical University General Hospital. The hemoglobin and blood loss of ICU patients were analyzed retrospectively. The general data, admission diagnosis, basic hemoglobin (Hb) value, acute physiology and chronic health score (APACHE 鈪,
本文編號:2303665
[Abstract]:Objective: to describe the current status of anemia in patients with ICU and to understand the process and possible causes of hemoglobin changes in patients with non-hemorrhagic sepsis. Methods: all the patients with ICU were collected from January 1 to December 31, 2015 in Ningxia Medical University General Hospital. The hemoglobin and blood loss of ICU patients were analyzed retrospectively. The general data, admission diagnosis, basic hemoglobin (Hb) value, acute physiology and chronic health score (APACHE 鈪,
本文編號:2303665
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