【摘要】：目的了解2016年安徽省銅陵市人民醫(yī)院臨床所有分離細(xì)菌的分布情況及耐藥性變遷。方法收集2016年所有臨床分離細(xì)菌并作藥敏試驗(yàn),結(jié)果統(tǒng)一輸入WHONET5.6軟件統(tǒng)計(jì)分析。結(jié)果 2016年共收集細(xì)菌2 949株,其中革蘭陰性菌2 134株(72.4%),革蘭陽性菌815株(27.6%)。革蘭陰性菌數(shù)量居前5位是大腸埃希菌、鮑曼不動(dòng)桿菌、肺炎克雷伯菌、銅綠假單胞菌和腸桿菌屬細(xì)菌;革蘭陽性菌數(shù)量居前5位是凝固酶陰性葡萄球菌、金黃色葡萄球菌、糞腸球菌、屎腸球菌和鏈球菌屬。產(chǎn)ESBL大腸埃希菌和肺炎克雷伯菌分別占各自菌數(shù)量的42.3%和31.1%,耐碳青霉烯類大腸埃希菌和肺炎克雷伯菌的檢出率為1.2%(8/640)和29.4%(108/367),鮑曼不動(dòng)桿菌對(duì)替加環(huán)素的敏感率為94.3%,對(duì)亞胺培南和美羅培南的耐藥率為74.3%和74.9%,銅綠假單胞菌對(duì)哌拉西林的敏感率為78.2%,對(duì)碳青霉烯類抗生素的敏感率在70%左右;耐甲氧西林金黃色葡萄球菌分離率32.0%(74/231),耐甲氧西林凝固酶陰性葡萄球菌分離率65.6%(170/259),沒有發(fā)現(xiàn)對(duì)替考拉寧和萬古霉素耐藥的葡萄球菌屬;未檢出替考拉寧和利奈唑胺耐藥的腸球菌屬細(xì)菌(糞腸球菌和屎腸球菌)。結(jié)論該院各類細(xì)菌分離數(shù)量呈逐年上升趨勢,多重耐藥菌的分離率逐年增長,泛耐藥腸桿菌科細(xì)菌及鮑曼不動(dòng)桿菌分離率的逐年增長趨勢十分嚴(yán)峻,迫切需要繼續(xù)加強(qiáng)醫(yī)院感染管理工作。
[Abstract]:Objective to investigate the distribution and drug resistance of all clinical bacteria isolated from Tongling people's Hospital of Anhui Province in 2016. Methods all clinical bacteria isolated in 2016 were collected and tested for drug sensitivity. The results were analyzed by WHONET5.6 software. Results A total of 2 949 strains of bacteria were collected in 2016, of which 2 134 (72.4%) were Gram-negative bacteria and 815 (27.6%) Gram-positive bacteria. The first 5 gram-negative bacteria were Escherichia coli, Acinetobacter baumannii, Klebsiella pneumoniae, Pseudomonas aeruginosa and Enterobacter spp. Enterococcus faecalis, Enterococcus faecium and Streptococcus. ESBL producing Escherichia coli and Klebsiella pneumoniae accounted for 42.3% and 31.1%, respectively. The detection rates of carbapene-resistant Escherichia coli and Klebsiella pneumoniae were 1.2% (8 / 640) and 29.4% (108 / 367), respectively. The sensitivity of Acinetobacter baumannii to tegacyclin was 94.3%. The drug resistance rates of imipenem and meropenem were 74.3% and 74.9%, the sensitivity rate of Pseudomonas aeruginosa to piperacillin was 78.2%, and the sensitivity rate to carbapenem antibiotics was about 70%. The isolation rates of methicillin-resistant Staphylococcus aureus and methicillin-resistant coagulase-negative staphylococcus were 32.0% (74 / 231) and 65.6% (170 / 259), respectively. Teicoplanin and renazolamide resistant Enterococcus bacteria (Enterococcus faecalis and Enterococcus faecium) were not detected. Conclusion the number of bacteria in this hospital is increasing year by year, the isolation rate of multidrug resistant bacteria is increasing year by year, and the isolation rate of pan-drug-resistant Enterobacteriaceae and Acinetobacter baumannii is very serious. There is an urgent need to continue to strengthen the management of nosocomial infection.
【作者單位】： 安徽省銅陵市人民醫(yī)院檢驗(yàn)科;
【分類號(hào)】：R446.5
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本文編號(hào)：2258245