承德市體檢人群甲狀腺結節(jié)患病情況及危險因素研究
發(fā)布時間：2018-09-07 21:07
【摘要】：目的:通過對承德市體檢人群甲狀腺結節(jié)患病情況的橫斷面研究,了解承德市體檢人群甲狀腺結節(jié)患病率情況;在此基礎上自行編制具有承德特色的甲狀腺結節(jié)相關因素調查問卷,用于體檢人群甲狀腺結節(jié)患病危險因素的病例對照研究,了解其患甲狀腺結節(jié)的危險因素,為制定承德市甲狀腺結節(jié)防治措施、臨床醫(yī)護人員進行健康宣教提供理論指導和科學依據(jù)。方法:本課題采用以體檢人群為基礎的橫斷面調查及病例對照研究方法,收集2015年1月~2016年1月在承德市某三甲醫(yī)院健康體檢中心查體的18~90歲體檢者的血液生化檢查、B型超聲檢查、體格檢查及身體測量等檢測項目的結果,描述性分析承德市體檢人群中甲狀腺結節(jié)患病率及其它疾病的檢出情況;同時在體檢人群中選取符合診斷標準的200例新發(fā)甲狀腺結節(jié)陽性者作為病例組,按照同期、年齡(±3歲)選取無甲狀腺結節(jié)的200例體檢者作為對照組,應用自編的《甲狀腺結節(jié)相關因素調查問卷》對兩組人群生活飲食、社會心理及疾病家族史等影響因素進行問卷調查,數(shù)據(jù)整理后,進行單因素及多因素非條件logistic回歸分析,進一步探討承德市體檢人群甲狀腺結節(jié)患病的相關危險因素。結果:1承德市體檢人群甲狀腺結節(jié)橫斷面研究結果:6000例健康體檢居民中,有效的統(tǒng)計數(shù)據(jù)資料為5462例(男性3218例、女性2244例)。甲狀腺結節(jié)總患病率為40.72%,其中女性人群甲狀腺結節(jié)患病率為42.47%,男性人群甲狀腺結節(jié)患病率為39.53%,女性甲狀腺結節(jié)患病率高于男性,差異有統(tǒng)計學意義(χ2=4.64,P=0.031)。甲狀腺結節(jié)患病率與年齡的增長成正相關趨勢,60歲年齡段人群結節(jié)患病率最高,達到64.19%。多因素分析發(fā)現(xiàn)年齡(OR=1.032,P=0.000)、體重指數(shù)(OR=1.021,P=0.042)、空腹血糖(OR=2.101,P=0.037)是體檢人群中甲狀腺結節(jié)患病率較高的獨立影響因素。2承德市體檢人群甲狀腺結節(jié)危險因素病例對照研究結果:經單因素及多因素非條件Logistic回歸分析后,甲狀腺疾病家族史(OR=5.17,P=0.010)、長期熬夜(OR=4.87,P=0.010)、經常生氣(OR=3.32,P=0.000)及食用碘鹽(OR=3.13,P=0.000)可能為體檢人群患甲狀腺結節(jié)的危險因素;家庭生活關系和諧(OR=-1.07,P=0.000)、積極的自我看法(OR=-0.44,P=0.016)可能為體檢人群患甲狀腺結節(jié)的保護因素。結論:1承德市體檢人群甲狀腺結節(jié)總患病率為40.72%。其中,女性甲狀腺結節(jié)患病率氋于男性,且患病率隨年齡增長而逐漸升高,60歲年齡段人群結節(jié)患病率高達64.19%,提示:應對我市居民甲狀腺結節(jié)的流行現(xiàn)況引起更多關注。2甲狀腺結節(jié)受多種影響因素的綜合作用,建議居民及高危人群應該從膳食、生活方式、改善社會心理環(huán)境等多方面采取預防控制措施,對年齡60歲及有甲狀腺疾病家族史的高危人群,應重點進行監(jiān)測,以期預防疾病的發(fā)生。
[Abstract]:Objective: to investigate the prevalence rate of thyroid nodules in healthy people in Chengde city by cross-sectional study. On the basis of this, the questionnaire of thyroid nodule related factors with Chengde characteristic was compiled, which was used in the case-control study of thyroid nodule risk factors in physical examination population to find out the risk factors of thyroid nodule. In order to make the prevention and cure measures of thyroid nodule in Chengde City, and provide the theory guidance and scientific basis for the health education of the clinical medical staff. Methods: a cross-sectional investigation and a case-control study based on physical examination were used in this study. From January 2015 to January 2016, the results of the blood biochemical examination, physical examination and physical measurement of 180-year-old people who were examined in the health examination center of a third Class A Hospital in Chengde City were collected, such as B-mode ultrasound examination, physical examination and physical measurement, etc. The prevalence of thyroid nodules and the detection of other diseases were analyzed in Chengde City, and 200 newly diagnosed thyroid nodule positive patients were selected as the case group according to the same period. The age (鹵3 years) of 200 healthy persons without thyroid nodule were selected as control group. The self-designed questionnaire of thyroid nodule related factors was used to investigate the influencing factors such as diet, social psychology and family history of disease in the two groups. Univariate and multivariate non-conditional logistic regression analysis was carried out to further explore the risk factors of thyroid nodule in healthy population in Chengde city. Results the results of the cross-sectional study of thyroid nodules in the population in Chengde City showed that the effective statistical data were 5462 cases (3218 males and 2244 females) out of 6 000 healthy residents. The total prevalence rate of thyroid nodules was 40.72%. The prevalence rate of thyroid nodules was 42.47 in female population and 39.53 in male population. The prevalence rate of thyroid nodule in female was higher than that in male (蠂 ~ 2 = 4.64) (蠂 ~ 2 = 4.64). The incidence of thyroid nodule was positively correlated with the increase of age. The prevalence rate of thyroid nodule was the highest in the age group of 60 years old, reaching 64.19%. Multivariate analysis found that age (OR=1.032,P=0.000), body mass index (OR=1.021,P=0.042) and fasting blood glucose (OR=2.101,P=0.037) were independent factors influencing the prevalence of thyroid nodules. After univariate and multivariate unconditioned Logistic regression analysis, Family history of thyroid disease (OR=5.17,P=0.010), long stay up (OR=4.87,P=0.010), frequent anger (OR=3.32,P=0.000) and iodized salt (OR=3.13,P=0.000) may be the risk factors of thyroid nodule in healthy people. Harmonious family life (OR=-1.07,P=0.000) and positive self-perception (OR=-0.44,P=0.016) may be the protective factors for thyroid nodules. Conclusion the total prevalence rate of thyroid nodules in the population in Chengde City is 40.72. Among them, the prevalence of thyroid nodules in females was higher than that in males. The prevalence rate of thyroid nodules increased gradually with the increase of age, and the prevalence rate of thyroid nodules was 64.19, which suggested that more attention should be paid to the prevalence of thyroid nodules in the residents of our city. It is suggested that the residents and high risk groups should take preventive and control measures from the aspects of diet, lifestyle, and improvement of social and psychological environment, and should focus on monitoring the high risk population aged 60 years and having a family history of thyroid diseases. In order to prevent the occurrence of disease.
【學位授予單位】：承德醫(yī)學院
【學位級別】：碩士
【學位授予年份】：2017
【分類號】：R473.5
本文編號：2229420
[Abstract]:Objective: to investigate the prevalence rate of thyroid nodules in healthy people in Chengde city by cross-sectional study. On the basis of this, the questionnaire of thyroid nodule related factors with Chengde characteristic was compiled, which was used in the case-control study of thyroid nodule risk factors in physical examination population to find out the risk factors of thyroid nodule. In order to make the prevention and cure measures of thyroid nodule in Chengde City, and provide the theory guidance and scientific basis for the health education of the clinical medical staff. Methods: a cross-sectional investigation and a case-control study based on physical examination were used in this study. From January 2015 to January 2016, the results of the blood biochemical examination, physical examination and physical measurement of 180-year-old people who were examined in the health examination center of a third Class A Hospital in Chengde City were collected, such as B-mode ultrasound examination, physical examination and physical measurement, etc. The prevalence of thyroid nodules and the detection of other diseases were analyzed in Chengde City, and 200 newly diagnosed thyroid nodule positive patients were selected as the case group according to the same period. The age (鹵3 years) of 200 healthy persons without thyroid nodule were selected as control group. The self-designed questionnaire of thyroid nodule related factors was used to investigate the influencing factors such as diet, social psychology and family history of disease in the two groups. Univariate and multivariate non-conditional logistic regression analysis was carried out to further explore the risk factors of thyroid nodule in healthy population in Chengde city. Results the results of the cross-sectional study of thyroid nodules in the population in Chengde City showed that the effective statistical data were 5462 cases (3218 males and 2244 females) out of 6 000 healthy residents. The total prevalence rate of thyroid nodules was 40.72%. The prevalence rate of thyroid nodules was 42.47 in female population and 39.53 in male population. The prevalence rate of thyroid nodule in female was higher than that in male (蠂 ~ 2 = 4.64) (蠂 ~ 2 = 4.64). The incidence of thyroid nodule was positively correlated with the increase of age. The prevalence rate of thyroid nodule was the highest in the age group of 60 years old, reaching 64.19%. Multivariate analysis found that age (OR=1.032,P=0.000), body mass index (OR=1.021,P=0.042) and fasting blood glucose (OR=2.101,P=0.037) were independent factors influencing the prevalence of thyroid nodules. After univariate and multivariate unconditioned Logistic regression analysis, Family history of thyroid disease (OR=5.17,P=0.010), long stay up (OR=4.87,P=0.010), frequent anger (OR=3.32,P=0.000) and iodized salt (OR=3.13,P=0.000) may be the risk factors of thyroid nodule in healthy people. Harmonious family life (OR=-1.07,P=0.000) and positive self-perception (OR=-0.44,P=0.016) may be the protective factors for thyroid nodules. Conclusion the total prevalence rate of thyroid nodules in the population in Chengde City is 40.72. Among them, the prevalence of thyroid nodules in females was higher than that in males. The prevalence rate of thyroid nodules increased gradually with the increase of age, and the prevalence rate of thyroid nodules was 64.19, which suggested that more attention should be paid to the prevalence of thyroid nodules in the residents of our city. It is suggested that the residents and high risk groups should take preventive and control measures from the aspects of diet, lifestyle, and improvement of social and psychological environment, and should focus on monitoring the high risk population aged 60 years and having a family history of thyroid diseases. In order to prevent the occurrence of disease.
【學位授予單位】：承德醫(yī)學院
【學位級別】：碩士
【學位授予年份】：2017
【分類號】：R473.5
【參考文獻】
相關期刊論文 前10條
1 諸駿仁;高潤霖;趙水平;陸國平;趙冬;李建軍;;中國成人血脂異常防治指南(2016年修訂版)[J];中國循環(huán)雜志;2016年10期
2 于釧釧;王強;;2008—2014年我國健康成人甲狀腺結節(jié)流行特征及影響因素初步分析[J];環(huán)境與健康雜志;2016年05期
3 劉慧玲;張紅梅;;武漢居民甲狀腺疾病患病情況及危險因素調查[J];現(xiàn)代醫(yī)院;2015年12期
4 韓晴;黃漢林;;甲狀腺疾病影響因素研究進展[J];中國職業(yè)醫(yī)學;2015年03期
5 田曉玲;李彩艷;林鳳平;朱四民;陳冠亞;馬小秀;;代謝綜合征患者甲狀腺結節(jié)患病情況分析[J];中國臨床保健雜志;2015年03期
6 韓晴;黃漢林;;廣州市區(qū)部分三甲醫(yī)院放射工作人員甲狀腺異常及影響因素調查[J];中國職業(yè)醫(yī)學;2015年02期
7 劉言訓;劉佳;張濤;王璐;薛付忠;王萍;;基于縱向監(jiān)測隊列的2型糖尿病與甲狀腺結節(jié)的關聯(lián)性[J];山東大學學報(醫(yī)學版);2015年08期
8 韓俊霞;成興波;邵新宇;張萍;;尿碘含量與甲狀腺結節(jié)患病率的關系[J];江蘇醫(yī)藥;2015年03期
9 陶雅輝;畢菲菲;劉閣玲;;唐山市職業(yè)人群甲狀腺結節(jié)的患病情況[J];職業(yè)與健康;2015年03期
10 付穎;王金銳;;甲狀腺結節(jié)指南中超聲相關部分的解讀及問題探討[J];中國超聲醫(yī)學雜志;2015年01期
相關碩士學位論文 前3條
1 王嵐;機關、事業(yè)單位職工甲狀腺結節(jié)與焦慮、抑郁狀態(tài)的相關性研究[D];浙江大學;2015年
2 朱海峰;青島地區(qū)海港職工甲狀腺結節(jié)患病情況及影響因素分析[D];青島大學;2011年
3 莫哲;浙江省人群甲狀腺結節(jié)患病狀況以及影響因素分析[D];寧波大學;2011年
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