本文選題：合肥市 + 獻血者��； 參考：《中國輸血雜志》2017年05期

【摘要】：目的了解合肥市無償獻血者中人類免疫缺陷病毒(HIV)流行情況和HIV感染者的人口特征,指導招募低危獻血者,進而指導制定合適的血液篩查策略,降低經(jīng)血傳播HIV的風險。方法安徽省血液中心檢驗科采用1種國產(chǎn)三代酶聯(lián)免疫試驗(ELISA)試劑和1種進口四代ELISA試劑,以及核酸檢測(NAT)試劑進行HIV篩查,篩查反應性標本送確證實驗室進行確證。統(tǒng)計安徽省血液中心2014年1月-2015年12月HIV篩查呈反應性的獻血者確證結(jié)果進行回顧性分析。結(jié)果 2年時間內(nèi)ELISA試劑篩查了215 015份標本,篩查呈反應性并送確證實驗室標本554份,經(jīng)確證陽性41份(均為ELISA雙試劑反應性),確證陽性率為7.4%:其中男性38例,女性3例;小于30歲的有24例,占58.5%;首次獻血有32位,占78%。2年時間內(nèi),NAT篩查了203 999例標本,ELISA-/NAT+9例,經(jīng)鑒定均為陰性。結(jié)論近年來合肥市無償獻血者中HIV感染者較高,主要集中在30歲以下的首次男性獻血者,應做好這部分獻血者的咨詢工作,降低輸血傳播HIV的風險。
[Abstract]:Objective to investigate the prevalence of human immunodeficiency virus (HIV) and HIV infection among unpaid blood donors in Hefei, and to guide the recruitment of low risk blood donors, and to establish appropriate blood screening strategies to reduce the risk of transmission of HIV through blood. Methods the laboratory of Anhui Blood Center used one kind of domestic three generation Elisa reagent, one kind of imported four generation Elisa reagent, and one kind of nucleic acid test (NATA) reagent for HIV screening, and the screening reactive samples were sent to the confirmation laboratory for confirmation. From January 2014 to December 2015, the confirmed results of HIV screening in Anhui Blood Center were retrospectively analyzed. Results within 2 years, 215,015 samples were screened by Elisa reagent, 554 samples were screened and confirmed in laboratory. 41 samples were confirmed positive by Elisa. The positive rate was 7.4%: 38 males and 3 females; 24 cases (58.5%) were younger than 30 years old, 32 cases (78.2 years) were first donated blood samples were screened for ELISA-rnat in 78,999 cases, all of them were identified as negative. Conclusion in recent years, the HIV infection rate among the unpaid blood donors in Hefei is relatively high, mainly concentrated in the first time male blood donors under 30 years old. It is necessary to do a good job in counseling this part of blood donors to reduce the risk of blood transfusion and transmission of HIV.
【作者單位】： 安徽醫(yī)科大學第二附屬醫(yī)院檢驗科;安徽省血液中心;中國醫(yī)學科學院北京協(xié)和醫(yī)學院輸血研究所;
【基金】：國家自然科學基金資助項目(81171662)
【分類號】：R446.6;R512.91

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