發(fā)布時間：2018-06-04 22:12

  本文選題：體素內(nèi)不相干運動 + 高強(qiáng)度聚焦超聲　； 參考：《臨床放射學(xué)雜志》2017年05期

【摘要】：目的探討體素內(nèi)不相干運動擴(kuò)散加權(quán)成像(IVIM-DWI)評價高強(qiáng)度聚焦超聲(HIFU)治療子宮肌瘤早期療效應(yīng)用價值。方法回顧性分析HIFU治療的15個子宮肌瘤患者資料,治療前、1天后均行增強(qiáng)MRI(CEMRI)及IVIM-DWI檢查,IIVIM-DWI采用16個b值,利用軟件計算出D值、D*值及f值,并且獲取各參數(shù)值圖,采用獨立樣本t檢驗比較子宮肌瘤消融區(qū)域與術(shù)前瘤體及消融灶鄰近組織間各值的差異。結(jié)果子宮肌瘤的D值、D*值及f值分別為(0.79±0.10)×10~(-3)mm~2/s、(19.87±2.12)×10~(-3)mm~2/s及(25.2±2.7)%,子宮肌瘤消融區(qū)域的D值、D*值及f值分別為(1.37±0.45)×10~(-3)mm~2/s、(3.13±0.21)×10~(-3)mm~2/s及(9.5±0.7)%,消融灶鄰近組織D值、D*值及f值分別為(1.32±0.13)×10~(-3)mm~2/s、(3.99±0.11)×10~(-3)mm~2/s及(20.6±1.1)%。子宮肌瘤消融區(qū)域D值較術(shù)前明顯升高,兩者之間有統(tǒng)計學(xué)差異(P0.05),D*值、f值較術(shù)前明顯減低,兩者之間有統(tǒng)計學(xué)差異(P0.05),D*值、f值較消融灶鄰近組織減低,兩者之間有統(tǒng)計學(xué)差異(P0.05),D值無統(tǒng)計學(xué)差異。子宮肌瘤消融區(qū)域D*值及f值ROC曲線下面積分別為0.902、0.952,敏感度分別為92.8%、97.8%,特異度分別為61.2%、68.2%。結(jié)論IVIM-DWI的D*值、f值對子宮肌瘤HIFU術(shù)后療效評價具有重要的價值,f值效果較佳。
[Abstract]:Objective to evaluate the early efficacy of high intensity focused ultrasound (HIFU) in the treatment of uterine leiomyoma by IVIM-DWI. Methods the data of 15 patients with uterine leiomyoma treated with HIFU were retrospectively analyzed. Before and one day after treatment, enhanced MRI CE MRI) and IVIM-DWI examination were performed with 16 b values on IIVIM-DWI. The D value D * and f value were calculated by software, and all parameter maps were obtained. T test was used to compare the difference between the ablation area of uterine leiomyoma and the preoperative tumor and adjacent tissue. 緇撴灉瀛愬鑲岀槫鐨凞鍊，

本文編號：1979021