發(fā)布時(shí)間：2018-05-08 13:14

  本文選題：葡萄球菌 + 人��； 參考：《中華疾病控制雜志》2017年09期

【摘要】：目的掌握小學(xué)生金黃色葡萄球菌(金葡菌)的攜帶率,并探究菌株的抗生素耐藥性。方法對廣州市部分在校健康小學(xué)生進(jìn)行鼻拭子采樣,對分離的金葡菌進(jìn)行抗生素藥敏試驗(yàn)。結(jié)果 1 012名小學(xué)生中金葡菌的攜帶率為40.1%,耐甲氧西林金葡菌的攜帶率為1.2%,多重耐藥金葡菌的攜帶率為4.0%。金葡菌主要對青霉素、紅霉素和克林霉素耐藥;多重耐藥金葡菌的主要耐藥譜為同時(shí)對紅霉素、克林霉素及四環(huán)素耐藥和同時(shí)對紅霉素、克林霉素及頭孢西丁耐藥。多因子降維法結(jié)果顯示多重耐藥金葡菌對頭孢西丁、四環(huán)素和氯霉素同時(shí)耐藥的比例是非多重耐藥金葡菌的104.39倍。結(jié)論廣州市健康小學(xué)生金葡菌的攜帶率較高,呈現(xiàn)出多重耐藥狀態(tài),為指導(dǎo)社區(qū)兒童合理使用抗生素提供數(shù)據(jù)支持。
[Abstract]:Objective to study the antibiotic resistance of Staphylococcus aureus (Staphylococcus aureus) in primary school students. Methods nasal swabs were collected from some healthy pupils in Guangzhou and antibiotic susceptibility tests were performed on isolated Staphylococcus aureus. Results the carrying rate of Staphylococcus aureus, methicillin-resistant Staphylococcus aureus and multidrug resistant Staphylococcus aureus were 40.1, 1.2 and 4.0 respectively. Staphylococcus aureus was mainly resistant to penicillin, erythromycin and clindamycin, and multidrug resistant Staphylococcus aureus was resistant to erythromycin, clindamycin and tetracycline, as well as erythromycin, clindamycin and cefoxitin. The results of multifactorial dimensionality reduction showed that the proportion of multidrug resistant Staphylococcus aureus to cefoxitin, tetracycline and chloramphenicol was 104.39 times higher than that of non-multidrug resistant Staphylococcus aureus. Conclusion the carrying rate of Staphylococcus aureus among healthy primary school students in Guangzhou is high, showing multidrug resistance, which provides data support for instructing children in community to use antibiotics rationally.
【作者單位】： 廣東藥科大學(xué)公共衛(wèi)生學(xué)院;
【基金】：國家自然科學(xué)基金(81602901) 廣東省科技計(jì)劃項(xiàng)目(2014A020212306) 廣東藥學(xué)院大學(xué)生創(chuàng)新創(chuàng)業(yè)培育項(xiàng)目(2015年)
【分類號】：R446.5

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