本文選題：動脈自旋標(biāo)記 + 腦�。� 參考：《南方醫(yī)科大學(xué)學(xué)報》2017年09期

【摘要】：目的研究正常成人腦部皮層下灰質(zhì)結(jié)構(gòu)3D假連續(xù)快速自旋回波動脈自旋標(biāo)記(3D pc-ASL)灌注的可重復(fù)性。方法對8例健康成年人進(jìn)行腦部3D pc-ASL序列及3D結(jié)構(gòu)像掃描,同一時間間隔一周后再次進(jìn)行掃描。對3D結(jié)構(gòu)像進(jìn)行皮層下灰質(zhì)結(jié)構(gòu)(殼核、蒼白球、尾狀核、丘腦、杏仁核、海馬)分割,并將3D pc-ASL進(jìn)行計算生成腦血流(CBF)圖,基于分割后的圖像及CBF圖進(jìn)行皮層下灰質(zhì)結(jié)構(gòu)CBF值提取。對于兩次測量結(jié)果采用組內(nèi)相關(guān)系數(shù)(ICC)及Bland-Altman圖分析。結(jié)果皮層下灰質(zhì)結(jié)構(gòu)的ICC值為0.80-0.93,均值為0.88±0.04。Bland-Altman圖形分析證實所有皮層下灰質(zhì)結(jié)構(gòu)對應(yīng)的點(diǎn)均位于95%一致性界限內(nèi)。結(jié)論 3D pc-ASL是一個可靠的評估腦部皮層下灰質(zhì)核團(tuán)灌注的序列。
[Abstract]:Objective to study the reproducibility of 3D pseudo-continuous fast spin-labeled arterial spin-labeling (3D pc-ASL) perfusion of subcortical gray matter in normal adults.Methods 3D pc-ASL sequences and 3D structural images of brain were performed in 8 healthy adults and were scanned again at the same time interval of one week.Subcortical gray matter (putamen nucleus, globus pallidus, caudate nucleus, thalamus, amygdala, hippocampus) was segmented from 3D structure image, and cerebral blood flow (CBF) was calculated by 3D pc-ASL.Based on the segmented image and CBF image, the CBF value of subcortical gray matter structure was extracted.The results of two measurements were analyzed by ICC and Bland-Altman.Results the ICC value of the subcortical gray matter structure was 0.80-0.93.The mean value was 0.88 鹵0.04.Bland-Altman. The results showed that all the points corresponding to the subcortical gray matter structure were within the 95% consistency limit.Conclusion 3D pc-ASL is a reliable sequence for evaluating subcortical gray nucleus perfusion.
【作者單位】： 中國人民解放軍總醫(yī)院海南分院放射科;中國人民解放軍總醫(yī)院放射科;
【分類號】：R445.2
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本文編號：1770053