基于生存分析的美沙酮維持治療患者脫失及影響因素研究
發(fā)布時(shí)間:2018-03-10 15:05
本文選題:美沙酮維持治療 切入點(diǎn):脫失 出處:《河南預(yù)防醫(yī)學(xué)雜志》2017年04期 論文類型:期刊論文
【摘要】:目的探討美沙酮維持治療患者脫失及其影響因素,為提供干預(yù)措施提供科學(xué)依據(jù)。方法收集福田區(qū)和南山區(qū)2009-2014年所有美沙酮維持治療患者相關(guān)信息,使用Kaplan-Meier法進(jìn)行單因素分析,根據(jù)單因素結(jié)果選擇有意義的變量進(jìn)入Cox比例風(fēng)險(xiǎn)模型進(jìn)行生存分析。結(jié)果共收集694例研究對(duì)象,5年累計(jì)脫失率為82.42%,研究發(fā)現(xiàn)無業(yè),獨(dú)居,靠臨時(shí)工資生活,公安部門介紹參加治療,靜脈和其他方式混合吸毒,吸毒年限在10~15 a,日服用劑量≤30mL,合并感染丙肝,梅毒或艾滋病均為美沙酮維持治療門診患者脫失的危險(xiǎn)因素。結(jié)論美沙酮門診脫失率較高,嚴(yán)重影響門診治療效果,應(yīng)根據(jù)危險(xiǎn)因素,提供針對(duì)性的干預(yù)措施,有效降低門診脫失率。
[Abstract]:Objective to investigate the loss of methadone maintenance therapy and its influencing factors, and to provide scientific basis for intervention measures. Methods the information of all methadone maintenance patients from 2009 to 2014 in Futian District and Nanshan District was collected and single factor analysis was performed by Kaplan-Meier method. According to the single factor results, significant variables were selected into the Cox proportional risk model for survival analysis. Results A total of 694 subjects were collected. The cumulative loss rate for 5 years was 82.42. The study found that they were unemployed, living alone and living on temporary wages. The public security department introduced taking part in treatment, intravenous and other mixed drug use. The drug use period was 1015a, daily dose 鈮,
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