本文選題：腦出血　切入點(diǎn)：磁共振成像　出處：《臨床放射學(xué)雜志》2017年09期 　論文類型：期刊論文

【摘要】：目的探討腦出血患者不同時(shí)間點(diǎn)磁共振擴(kuò)散張量成像(DTI)參數(shù)與肢體肌力恢復(fù)的相關(guān)性。方法前瞻性搜集2015年5月至2016年5月基底節(jié)區(qū)腦出血患者76例,分別在入院時(shí)和入院后2周進(jìn)行DTI掃描,重組皮質(zhì)脊髓束(CST),并根據(jù)CST完整性分為1~4級(jí),并采用簡式Fugl-Meye運(yùn)動(dòng)功能(FMS)評(píng)分評(píng)估患者入院時(shí)和入院后2周以及末次隨訪(≥18個(gè)月)的肌力,分析DTI參數(shù)與肌力恢復(fù)的相關(guān)性。結(jié)果入院時(shí)不同CST分級(jí)的腦出血患者其病變側(cè)部分各向異性分?jǐn)?shù)(FA)值為1級(jí)2級(jí)3級(jí)4級(jí),差異均有統(tǒng)計(jì)學(xué)意義(P0.05)。入院時(shí)和末次隨訪時(shí)CST 1~2級(jí)患者的FMS評(píng)分顯著高于3~4級(jí)者,差異均有統(tǒng)計(jì)學(xué)意義(P0.05),1級(jí)和2級(jí)之間的FMS評(píng)分差異無統(tǒng)計(jì)學(xué)意義(P0.05)。入院2周時(shí)不同CST分級(jí)的腦出血患者其病變側(cè)FA值為1級(jí)2級(jí)3級(jí)4級(jí),差異均有統(tǒng)計(jì)學(xué)意義(P0.05)。入院2周和末次隨訪時(shí)不同CST分級(jí)患者的FMS評(píng)分為1級(jí)2級(jí)3級(jí)4級(jí),差異均有統(tǒng)計(jì)學(xué)意義(P0.05)。入院時(shí)病變側(cè)的FA值與入院時(shí)的FMS評(píng)分呈顯著正相關(guān)(r=0.653,P=0.012),而與末次隨訪時(shí)的FMS無顯著相關(guān)性(r=0.326,P=0.053)。入院2周時(shí)病變側(cè)的FA值與入院時(shí)的FMS評(píng)分和末次隨訪時(shí)的FMS均呈顯著正相關(guān)(r=0.598,0.523,P=0.016,0.025)。結(jié)論腦出血患者不同時(shí)間點(diǎn)的DTI參數(shù)與患者的肌力均有關(guān),與入院時(shí)相比,入院后2周的DTI參數(shù)與患者的肌力恢復(fù)的關(guān)系更為密切。
[Abstract]:Objective to investigate the correlation between DTI parameters and limb muscle strength recovery in patients with intracerebral hemorrhage at different time points. Methods 76 patients with basal ganglia intracerebral hemorrhage from May 2015 to May 2016 were prospectively collected. DTI scans were performed on admission and 2 weeks after admission to reconstitute the corticospinal bundles. According to the integrity of CST, they were divided into 1 and 4 grades. The muscle strength of patients at admission, 2 weeks after admission and at the last follow-up (鈮，

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