發(fā)布時(shí)間：2018-02-17 04:14

  本文關(guān)鍵詞： 垂體腺瘤 磁共振波譜成像 膽堿 肌酸 N-乙酰天門冬氨酸　出處：《放射學(xué)實(shí)踐》2017年04期 　論文類型：期刊論文

【摘要】：目的:探討~1H-磁共振波譜成像(~1H-MRS)對(duì)侵襲性垂體腺瘤的診斷價(jià)值。方法:對(duì)56例經(jīng)病理證實(shí)的垂體腺瘤患者的~1H-MRS數(shù)據(jù)進(jìn)行回顧性分析,其中侵襲性36例、非侵襲性20例。測(cè)量和計(jì)算兩組患者病變區(qū)的膽堿(Cho)/肌酸(Cr)、N-乙酰天門冬氨酸(NAA)/Cr、肌醇(MI)/Cr、乳酸脂質(zhì)(LL)/Cr及Cho/NAA的值,并進(jìn)行統(tǒng)計(jì)學(xué)分析。結(jié)果:Cho/Cr、LL/Cr、MI/Cr、NAA/Cr及Cho/NAA的值在侵襲性組中分別為3.913±2.091、2.435±1.645、1.466±1.319、1.169±0.781及3.865±1.890,在非侵襲性組中分別為1.796±0.612、3.552±2.716、1.340±1.010、1.069±0.774和1.799±0.581,兩組間僅Cho/NAA和Cho/Cr的差異有統(tǒng)計(jì)學(xué)意義(P0.05)。受試者工作特征(ROC)曲線分析顯示,當(dāng)Cho/NAA值大于2.045時(shí),診斷侵襲性垂體腺瘤的敏感度為89.9%,特異度為80.0%,符合率為88.5%;當(dāng)Cho/Cr值大于1.900時(shí),診斷侵襲性垂體腺瘤的敏感度為86.1%,特異度為65.0%,符合率為83.6%。結(jié)論:~1H-MRS對(duì)侵襲性垂體腺瘤的診斷具有一定參考價(jià)值。
[Abstract]:Objective: to evaluate the diagnostic value of 1H-MRS in invasive pituitary adenomas. Methods: retrospective analysis was performed in 56 cases of pituitary adenomas confirmed by pathology, including 36 cases of invasive pituitary adenomas. Twenty cases of noninvasive. The values of choline chorion / creatine (Cr) -acetyl aspartic acid (NAA / Cr), inositol (Mi / Cr), lactate lipids (LLX / Cr) and Cho/NAA were measured and calculated in the two groups. Results the values of NAA / Cr and Cho/NAA in the invasive group were 3.913 鹵2.091 鹵2.435 鹵1.6451.466 鹵1.3191.169 鹵0.781 and 3.865 鹵1.890, respectively, and 1.796 鹵0.6123.552 鹵2.716 鹵1.340 鹵1.0101.069 鹵0.774 and 1.799 鹵0.581in the non-invasive group, respectively. The difference between the two groups was significant (P 0.05). When the Cho/NAA value was greater than 2.045, the sensitivity, specificity and coincidence rate of diagnosis of invasive pituitary adenomas were 89.9, 80.0and 88.5respectively, and when the Cho/Cr value was greater than 1.900, the sensitivity and specificity were 80.0 and 87.5, respectively. The sensitivity, specificity and coincidence rate of diagnosis of invasive pituitary adenomas were 86.1 and 65.0 respectively.
【作者單位】： 第三軍醫(yī)大學(xué)新橋醫(yī)院放射科;
【基金】：國家自然科學(xué)基金(81501521)
【分類號(hào)】：R445.2;R736.4

【相似文獻(xiàn)】

相關(guān)期刊論文 前2條

1 何美霖;夏莉;;經(jīng)顱侵襲性垂體腺瘤切除手術(shù)后的護(hù)理體會(huì)[J];內(nèi)蒙古中醫(yī)藥;2014年11期

2 ;[J];;年期

相關(guān)博士學(xué)位論文 前1條

1 張林;侵襲性垂體腺瘤和微腺瘤的MRI診斷與研究[D];山東大學(xué);2015年

，

本文編號(hào)：1517189