本文關(guān)鍵詞： 民族 不規(guī)則抗體 孕婦　出處：《青海大學(xué)》2017年碩士論文　論文類型：學(xué)位論文

【摘要】：目的通過檢測(cè)青海地區(qū)漢族、藏族、回族、土族及撒拉族五個(gè)民族孕婦的不規(guī)則抗體,以期發(fā)掘在臨床上具有意義的不規(guī)則抗體,初步摸索不規(guī)則抗體在五個(gè)民族的分布特征。方法對(duì)20l4年1月至2017年1月在青海紅十字醫(yī)院就診的漢族、藏族、回族、土族、撒拉族五個(gè)民族孕婦共11991例進(jìn)行不規(guī)則抗體的篩選及鑒定,獲取不規(guī)則抗體陽性率及其具體類型在青海地區(qū)五個(gè)民族孕婦中的分布特征。結(jié)果(1)青海地區(qū)五個(gè)民族孕婦不規(guī)則抗體陽性檢出率分別為:撒拉族孕婦為(1.89%)、回族孕婦為(1.05%)、土族孕婦為(0.50%)、藏族孕婦為(0.39%)、漢族孕婦為(0.35%);五個(gè)民族孕婦之間的不規(guī)則抗體陽性率比較:漢族、藏族孕婦分別與回族、撒拉族孕婦的不規(guī)則抗體陽性率比較,均P0.05差異有統(tǒng)計(jì)學(xué)意義,而其他民族之間孕婦不規(guī)則抗體陽性率比較,均P0.05差異無統(tǒng)計(jì)學(xué)意義;(2)五個(gè)民族孕婦中不規(guī)則抗體具體類型的出現(xiàn)頻率及分布存在差異性;(3)五個(gè)民族孕婦檢出63例不規(guī)則抗體,其中RH血型系統(tǒng)共54例最多見,不規(guī)則抗體以抗-D(19例)最多見,抗-E(14例)是其次,抗-c E(9例)、抗-c(7例)、抗-M(4例)也較多見,另外可見抗-e、抗-CD、抗-Lea、抗-P1、冷抗體;不規(guī)則抗體主要以Ig G類型抗體為主;(4)漢族、藏族、回族≥2次妊娠史孕婦的不規(guī)則抗體檢出率高于首次妊娠孕婦,均P0.05差異有統(tǒng)計(jì)學(xué)意義,而土族、撒拉族≥2次妊娠史孕婦的不規(guī)則抗體檢出率與首次妊娠孕婦相比較,均P0.05差異無統(tǒng)計(jì)學(xué)意義。結(jié)論(1)青海地區(qū)漢族、藏族、回族、土族及撒拉族五個(gè)民族孕婦不規(guī)則抗體及其具體類型的分布可能存在民族特異性;(2)臨床上除了常規(guī)進(jìn)行ABO血型鑒定、Rh D檢測(cè),需添加Rh E、Rhc E、Rhc等其他臨床常見不規(guī)則抗體檢測(cè),才能更好地避免HTR及HDN的發(fā)生。
[Abstract]:Objective to detect irregular antibodies of pregnant women of Han, Tibetan, Hui, Tu and Sala nationalities in Qinghai area, and to explore the clinical significance of irregular antibodies. Methods from January to January 2017 in Qinghai Red Cross Hospital, Han, Tibetan, Hui and Tu nationality were studied. A total of 11991 pregnant women from five nationalities of Salar nationality were screened and identified for irregular antibodies. The positive rate of irregular antibody and its specific types were obtained among the pregnant women of five nationalities in Qinghai area. Results the positive rate of irregular antibody in the pregnant women of five nationalities in Qinghai area was as follows: the positive rate of irregular antibody in the pregnant women of Salar nationality was (. 1.89). The number of pregnant women of the Hui nationality was 1.05%, that of the pregnant women of the Tu nationality was 0.50%, that of the pregnant women of the Tibetan nationality was 0.39%, and that of the pregnant women of the Han nationality was 0.35%. Comparison of irregular antibody positive rate among pregnant women of five nationalities: Han, Tibetan pregnant women and Hui, Sala pregnant women were compared with irregular antibody positive rate, all the differences were statistically significant (P0.05). However, there was no significant difference in the positive rate of irregular antibody among other ethnic groups (P0.05). (2) the frequency and distribution of irregular antibody in pregnant women of five nationalities were different. (3) 63 cases of irregular antibodies were detected in pregnant women of five nationalities, of which 54 cases were found in RH blood group system, 19 cases were irregular antibodies, and 14 cases were anti-EG). There were also 9 cases of anti -c Em, 7 cases of anti-cor, 4 cases of anti-MU). In addition, anti-E, anti-CD, anti-Lea, anti-P 1, cold antibody were also found. The irregular antibody was mainly IgG type antibody. 4) the detection rate of irregular antibody in pregnant women of Han, Tibetan and Hui nationalities 鈮，

本文編號(hào)：1472443