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小兒肺炎克雷伯菌下呼吸道感染臨床特點(diǎn)及耐藥率

發(fā)布時(shí)間:2018-01-04 15:05

  本文關(guān)鍵詞:小兒肺炎克雷伯菌下呼吸道感染臨床特點(diǎn)及耐藥率 出處:《中國(guó)感染控制雜志》2017年05期  論文類型:期刊論文


  更多相關(guān)文章: 兒童 下呼吸道感染 肺炎克雷伯菌 抗藥性 微生物 耐藥性 合理用藥


【摘要】:目的了解小兒下呼吸道肺炎克雷伯菌感染的臨床特征及其耐藥性。方法回顧性分析2015年1—12月經(jīng)痰培養(yǎng)確診為下呼吸道肺炎克雷伯菌感染的107例患兒臨床資料。結(jié)果 62.62%的患兒發(fā)病年齡為6個(gè)月內(nèi),64.49%的患兒為秋冬季節(jié)發(fā)病。臨床均有咳嗽,39例伴有發(fā)熱,主要并發(fā)癥為Ⅰ型呼吸衰竭、Ⅱ型呼吸衰竭、心功能不全、電解質(zhì)紊亂,其中兩個(gè)系統(tǒng)并發(fā)癥者39例(36.45%),三個(gè)系統(tǒng)并發(fā)癥者5例(4.67%),47例(43.93%)符合重癥肺炎診斷標(biāo)準(zhǔn)。43例(40.19%)有原發(fā)基礎(chǔ)性疾病,主要是先天性心臟病、早產(chǎn)和低體重兒、營(yíng)養(yǎng)不良。亞胺培南耐藥菌感染患兒較非耐藥菌感染患兒更易發(fā)生肺外并發(fā)癥。肺炎克雷伯菌對(duì)阿米卡星(9.35%)耐藥率最低。臨床痊愈和顯效90例,有效11例,4例未愈自動(dòng)出院,死亡2例。結(jié)論小兒下呼吸道肺炎克雷伯菌感染以年齡6個(gè)月內(nèi)、合并有原發(fā)基礎(chǔ)性疾病嬰兒發(fā)病率高,且并發(fā)癥多。
[Abstract]:Objective to investigate the clinical characteristics and drug resistance of Klebsiella pneumoniae infection in children. Methods 107 cases of Klebsiella pneumoniae infection in lower respiratory tract from 2015 to December were analyzed retrospectively. Clinical data of children. Results. 62.62% of the children were aged within 6 months. 64.49% of the children were diagnosed in autumn and winter. 39 cases of cough accompanied with fever were found. The main complications were type 鈪,

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