實時三維超聲心動圖評價肥胖對左房容積和功能的影響
發(fā)布時間:2017-12-28 08:03
本文關鍵詞:實時三維超聲心動圖評價肥胖對左房容積和功能的影響 出處:《中國超聲醫(yī)學雜志》2017年07期 論文類型:期刊論文
【摘要】:目的應用實時三維超聲心動圖(RT-3DE)探討肥胖和超重對左房(LA)容積和功能的影響。方法按體質量指數(shù)(BMI)將120例健康體檢者分為三組:肥胖組、超重組和對照組,應用RT-3DE檢測左房最大容積(LAVmax)、左房收縮前容積(LAVp)及左房最小容積(LAVmin),計算并比較各組間左房容積指數(shù)(LAVI)、LA總排空容積(LATEV)、LA總排空指數(shù)(LAEFt)、LA被動排空容積(LAPEV)、LA被動排空指數(shù)(LAEFp)、LA主動排空容積(LAAEV)、LA主動排空指數(shù)(LAEFa)。分析N末端腦利鈉肽前體(NT-proBNP)和左房容積及功能指標的相關性。結果 (1)對照組、超重組及肥胖組的LA容積指標(LAVmax、LAVp、LAVmin、LAVI)依次增大,儲存功能指標(LATEV)和LA泵功能指標(LAAEV、LAEFa)依次增大,而LA傳導功能指標(LAEFp)則依次減小。(2)肥胖組NTproBNP水平稍高于超重組和對照組,差異無統(tǒng)計學意義。NT-proBNP與LAVI、LAVmax、LAVmin、LATEV及LAAEV具有一定相關性。結論肥胖及超重可在無心血管疾病癥狀前引起左房結構和機械功能受損。RT-3DE可以靈敏地檢測出上述亞臨床改變。
[Abstract]:Objective to investigate the effect of obesity and overweight on the volume and function of left atrial (LA) by real time three-dimensional echocardiography (RT-3DE). Methods according to body mass index (BMI) and 120 healthy subjects were divided into three groups: the overweight and obesity group, control group, left atrial volume measured by RT-3DE maximum (LAVmax), left atrial systolic volume (LAVp) and minimum left atrial volume (LAVmin), left atrial volume index were calculated and compared between LA (LAVI), total emptying volume (LATEV), LA index (LAEFt), total emptying LA passive emptying volume (LAPEV), LA index (LAEFp), passive emptying LA active emptying volume (LAAEV), LA active emptying index (LAEFa). The correlation between the N terminal brain natriuretic peptide precursor (NT-proBNP), the left atrial volume and the functional indexes was analyzed. Results (1) the LA volume index (LAVmax, LAVp, LAVmin and LAVI) increased in control group, overweight group and obesity group. Storage function index (LATEV) and LA pump function index (LAAEV and LAEFa) increased in sequence, while LA conduction function index (LAEFp) decreased in turn. (2) the level of NTproBNP in the obese group was slightly higher than that in the super recombinant and the control group, with no statistical difference. NT-proBNP has a certain correlation with LAVI, LAVmax, LAVmin, LATEV and LAAEV. Conclusion obesity and overweight can cause damage to the left atrial structure and mechanical function before the symptoms of cardiovascular disease. RT-3DE can be used to detect these subclinical changes sensitively.
【作者單位】: 西安交通大學第二附屬醫(yī)院超聲科;
【分類號】:R540.45;R589.2
【正文快照】: 結果(1)對照組、超重組及肥胖組的LA容積指標(LAVmax、LAVp、LAVmin、LAVI)依次增大,儲存功能指標(LATEV)和LA泵功能指標(LAAEV、LAEFa)依次增大,而LA傳導功能指標(LAEFp)則依次減小。(2)肥胖組NT-proBNP水平稍高于超重組和對照組,差異無統(tǒng)計學意義。NT-proBNP與LAVI、LAVmax,
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