【摘要】：[目的/意義]使用本體對醫(yī)藥信息進(jìn)行組織和表示,不僅能夠在語義的層面上有效地管理和利用醫(yī)藥知識,而且能夠?qū)崿F(xiàn)領(lǐng)域知識的融合共享,推動醫(yī)藥領(lǐng)域的智能應(yīng)用。當(dāng)前對藥物本體的構(gòu)建主要借助規(guī)范化的醫(yī)學(xué)術(shù)語系統(tǒng),忽略了藥物適應(yīng)癥自然文本中隱含的藥物語義關(guān)聯(lián)。因此提出一種面向藥物適應(yīng)癥的領(lǐng)域本體構(gòu)建方法。[方法/過程]以"抗腫瘤藥物"為例,對265條藥物信息進(jìn)行處理;將適應(yīng)癥文本進(jìn)行語義補(bǔ)全,使用二次分詞和合并的方法抽取特征詞;利用形式概念分析,以"藥物—適應(yīng)癥"的關(guān)聯(lián)構(gòu)建形式背景并生成概念格,根據(jù)概念格的結(jié)構(gòu)對藥物關(guān)系進(jìn)行描述;使用OWL語言對概念格轉(zhuǎn)化而來的本體進(jìn)行描述。[結(jié)果/結(jié)論]對構(gòu)建的本體進(jìn)行一致性檢驗,并以可視化方式展示和分析。實驗表明該構(gòu)建方法能夠表示藥物與適應(yīng)癥的語義關(guān)聯(lián)。
[Abstract]:[objective / significance] Organization and representation of pharmaceutical information by ontology can not only effectively manage and utilize pharmaceutical knowledge at the semantic level, but also realize the fusion and sharing of domain knowledge and promote the intelligent application in the field of medicine. At present, the construction of drug ontology mainly relies on the standardized medical terminology system, ignoring the drug semantic association implied in the natural text of drug indications. Therefore, a domain ontology method for drug indication is proposed. [method / process] taking "antitumor drugs" as an example, 265 drug information were processed; the indication text was semantically completed, and the feature words were extracted using the method of secondary participle and combination. The formal background and concept lattice are constructed with the association of "drug indications", and the drug relations are described according to the structure of concept lattice, and the ontology transformed by concept lattice is described by OWL language. Results / conclusions: the conformance of the constructed ontology is verified, and visualized and analyzed. The experimental results show that this method can represent the semantic association between drugs and indications.
【作者單位】： 武漢大學(xué)信息系統(tǒng)研究中心;武漢大學(xué)信息管理學(xué)院;
【基金】：國家自然科學(xué)基金項目“基于文本和Web語義分析的智能咨詢服務(wù)研究”(編號:71673209)研究成果之一
【分類號】：R-05;TP391.1
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本文編號：2142263