AZ91HP鎂合金激光熔凝層的耐蝕性和生物相容性
本文選題:醫(yī)用鎂合金 + 激光熔凝層; 參考:《材料熱處理學(xué)報(bào)》2015年01期
【摘要】:為提高醫(yī)用AZ91HP鎂合金的耐蝕性和生物相容性,采用激光熔凝技術(shù)對鎂合金進(jìn)行熔凝處理。結(jié)果表明,AZ91HP鎂合金熔凝層相組成為α-Mg和β-Mg17Al12,凝固組織為典型的樹枝晶。模擬體液中腐蝕速率結(jié)果表明,熔凝層的耐蝕性較原始鎂合金顯著提高。在Hank’s中浸泡21 d后,可清楚看到一些絮狀物沉積在熔凝層表面;能譜分析結(jié)果表明,絮狀物中Ca,P比約為1.33,接近羥基磷灰石中Ca,P比(1.67)。原始鎂合金的凝血酶原時(shí)間(PT)值為11.025 s,激光熔凝層的PT值為12.025 s,熔凝層具有較好的抗凝血性。細(xì)胞毒性實(shí)驗(yàn)結(jié)果表明,培養(yǎng)1 d后,在原始鎂合金周圍細(xì)胞出現(xiàn)破碎和固縮,極少數(shù)貼壁細(xì)胞。熔凝層表面則存在許多粘附細(xì)胞,熔凝層細(xì)胞死亡率較原始鎂合金大有降低。
[Abstract]:In order to improve the corrosion resistance and biocompatibility of medical AZ91HP magnesium alloy, laser melting technology was used to melt the magnesium alloy. The results show that the melting layer of AZ91HP magnesium alloy consists of 偽 -Mg and 尾 -Mg17Al12.The solidification structure is a typical dendrite. The corrosion rate in simulated body fluid shows that the corrosion resistance of the melting layer is significantly higher than that of the original magnesium alloy. After being immersed in Hank's for 21 days, some flocculants were clearly deposited on the surface of the fused layer, and the results of energy spectrum analysis showed that the ratio of Ca-P to Ca-P in the flocculants was about 1.33, which was close to that in hydroxyapatite. The prothrombin time (PTT) of the original magnesium alloy was 11.025 s and the PT value of the laser fused layer was 12.025 s. The fusion layer had better anticoagulant effect. The results of cytotoxicity test showed that after 1 day of culture, the cells around the original magnesium alloy were broken and pyknotic, and a few adherent cells were observed. There are many adhesion cells on the surface of the melting layer, and the cell death rate of the fusion layer is much lower than that of the original magnesium alloy.
【作者單位】: 東北電力大學(xué)機(jī)械工程學(xué)院;中海石油華鶴煤化有限公司;
【基金】:東北電力大學(xué)青年學(xué)術(shù)骨干科研促進(jìn)計(jì)劃項(xiàng)目
【分類號】:TG174.4
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