【摘要】：自金屬配位化合物應(yīng)用于生活中各個方面以來,配位化合物的結(jié)構(gòu)和性質(zhì)的研究已成為當(dāng)今無機(jī)化學(xué)領(lǐng)域的熱點(diǎn)前沿問題。對于金屬配位化合物的研究,也隨之涉足于各個領(lǐng)域各個方面。本論文在不同有機(jī)溶劑中合成了一系列含有羧基或磺酸根基團(tuán)的多足配體,以鈣、鎂、鋅等原子為活性中心自組裝成結(jié)構(gòu)新穎的配合物。同時,利用單晶X-ray衍射儀和光譜分析儀等正確測定其結(jié)構(gòu)。在此基礎(chǔ)上,研究了金屬離子與不同配體的配位行為、配位特點(diǎn)及其結(jié)構(gòu)的規(guī)律性及差異性;通過對其生物活性(抗菌、抗腫瘤)及其催化性質(zhì)等方面的測試,進(jìn)一步探討其潛在的應(yīng)用價值。本文共合成十種不同的金屬配位化合物,并對其性質(zhì)進(jìn)行了測試。論文主要分為以下幾個部分:1、合成了以N-乙酰-L-苯丙氨酸為主要配體,以4,4’-聯(lián)吡啶和1,10-菲羅啉分別為輔助配體的兩個新型鋅的配合物{[Zn(L)_2(4,4’-bipy)]·(H_2O)}n(1)(L=N-乙酰-L-苯丙氨酸)和[Zn(L)_2(phen)·(H_2O)]n(2)(L=N-乙酰-L-苯丙氨酸),并用X-單晶衍射儀、紅外光譜儀、元素分析儀對兩種配合物的結(jié)構(gòu)進(jìn)行測試。此外,詳細(xì)測試了兩種新型配合物的生物活性。2、合成了以N-煙酰甘氨酸為配體的新型鎘、錳、鋅三種原子的配合物{[CdL_2(H_2O)]·(H_2O)_3}n(3)(L=N-煙酰甘氨酸)、[MnL·(H_2O)]n(4)(L=N-煙酰甘氨酸)、[{ZnL(H_2O)_2}·H_2O]n(5)(L=N-煙酰甘氨酸),用X-單晶衍射儀、紅外光譜儀、元素分析儀對三種新型配合物進(jìn)行了表征,并分析了三種物質(zhì)結(jié)構(gòu)的異同之處。3、合成了以1,4-亞苯基二乙酸為主要配體、2,2’-聯(lián)吡啶為輔助配體的銅的配位化合物[CuL(bipy)·(H_2O)_5]n(6)(L=4-亞苯基二乙酸),并用X-單晶衍射儀、紅外光譜儀、元素分析儀對其結(jié)構(gòu)進(jìn)行表征,并對其催化三組分偶聯(lián)反應(yīng)做了詳細(xì)的測試,結(jié)果表明,配合物6對該反應(yīng)具有較高的催化性能。4、合成了以4-甲�；�-1,3-苯二磺酸鈉縮2-糠酸酰肼、4-甲�；�-1,3-苯二磺酸鈉縮煙酰肼為配體的新型兩種鈣的配位化合物{[CaL·(H_2O)4]·(H_2O)4}n(7)(L=4-甲酰基-1,3-苯二磺酸鈉縮2-糠酸酰肼)、[CaL·(H_2O)_5]n(8)(L=4-甲�；�-1,3-苯二磺酸鈉縮煙酰肼);以4-氨基-3-甲基苯磺酸與鎂的新型配位化合物[Mg·(H_2O)6]·L_2(9)(L=4-氨基-3-甲基苯甲酸);以2-甲苯磺酸鈉縮2-糠酸酰肼為配體的新型鈣的配位化合物{[CaL_2·(H_2O)_2·2H_2O]}n(10)(L=2-甲苯磺酸鈉縮2-糠酸酰肼),并用X-單晶衍射儀、紅外光譜儀、元素分析儀對其結(jié)構(gòu)進(jìn)行了表征。
[Abstract]:Since the application of metal coordination compounds in various aspects of life, the study of the structure and properties of coordination compounds has become a hot topic in the field of inorganic chemistry. The study of metal coordination compounds also involved in various fields. In this paper, a series of polypodal ligands containing carboxyl or sulfonic groups were synthesized in different organic solvents, and self-assembled with calcium, magnesium and zinc atoms as active centers to form novel complexes. At the same time, the structure was determined by single crystal X-ray diffractometer and spectrometer. On this basis, the coordination behavior, coordination characteristics, structural regularity and difference of metal ions with different ligands were studied, and their biological activities (antimicrobial, anti-tumor) and their catalytic properties were tested. Further explore its potential application value. Ten different metal coordination compounds were synthesized and their properties were tested. This paper is divided into the following parts: 1. The main ligand of N-acetyl-L-phenylalanine was synthesized. Two new zinc complexes {[Zn (L) _ 2 (4H _ 2O _ 4)] (H _ 2O)} (H _ 2O)} n (1) (Zn (L) _ 2-acetyl-L-phenylalanine) and [Zn (L) _ 2 (phen) (H _ 2O)] n (2) (Lnacetyl-L-phenylalanine) were used as auxiliary ligands, respectively. The structure of the two complexes was tested by elemental analyzer. In addition, the biological activity of two new complexes was tested in detail, and the complexes {[CdL_2 (H2O)] (H2O) 3} n (LN- nicotinyl glycine), [MnL (H2O)] n (4) (LN- nicotinyl glycine), [{ZnL (H2O) 2} H2O] n (5) (LN- nicotinyl glycine) were synthesized by the synthesis of the complexes {[CdL_2 (H2O)] (H2O) (H2O) 3} n (LN- nicotinyl glycine), [{ZnL (H2O) 2} H2O] n (5) (LN- nicotinyl glycine), and [ZnL (H2O) 2} H2O] n (5) (LN- nicotinyl glycine). The three new complexes were characterized by infrared spectrometer and elemental analyzer. In this paper, the similarities and differences of three compounds were analyzed, and the coordination compound [CuL (bipy) (H2O] 5] n (6) (Ln 4phenylene diacetic acid) was synthesized with 1h4phenylene diacetic acid as the main ligands, [CuL (bipy) (H2O] 5] n (Ln 4- phenylenediacetic acid), and was characterized by X-ray single crystal diffractometer and infrared spectrometer. Its structure was characterized by elemental analyzer, and its catalytic three-component coupling reaction was tested in detail. Complex 6 has high catalytic activity for this reaction. A new calcium coordination compound {[CaL (H2O) 4] (H2O) 4} n (7) (Ln 4- formyl) n (7) (Ln 4- formylformyl) n (7) was synthesized with sodium 4-furanoyl hydrazide (2-furoic acid) 4-formylhydrazide as ligand, and the coordination compound {[CaL (H2O) 4] (H2O) 4} n (Ln 4- formyl) was synthesized by using complex 6 as the ligand of this reaction. The coordination compound {[CaL (H2O) 4] (H2O) 4} n (Ln 4- formyl) was synthesized. [CaL (H2O) 5] n (8) (L4 formyl-1-3-benzenesulfonate sodium nicotinyl hydrazide); a new coordination compound of magnesium with 4-amino-3-methyl benzenesulfonic acid [mg (hs) 2O 6] L 2 (9) (Ln (H2O) 5] n (8); sodium 2- toluenesulfonate 2-furanyl acid A new calcium coordination compound {[CaL_2 (H _ S _ 2O) _ 2 2H_2O]} _ n (10) (sodium Ln _ 2-toluenesulfonate _ 2-furoic acid hydrazide) with hydrazine as ligand was used by X-ray diffraction. Its structure was characterized by infrared spectrometer and elemental analyzer.
【學(xué)位授予單位】：青海師范大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：O641.4

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