本文選題：抗阻力量訓(xùn)練 + 成年男性��； 參考：《上海體育學(xué)院》2017年碩士論文

【摘要】：研究目的:研究表明身體活動(dòng)與體內(nèi)循環(huán)維生素D濃度存在正相關(guān)關(guān)系,并且發(fā)現(xiàn)即使排除了陽(yáng)光曝露的影響后,關(guān)系依然存在。然而相關(guān)的研究大部分為觀察類研究,無(wú)法得出二者之間的因果關(guān)系,為數(shù)不多的探究運(yùn)動(dòng)鍛煉與循環(huán)維生素D關(guān)系的干預(yù)研究由于實(shí)驗(yàn)設(shè)計(jì)的不足也不能得出準(zhǔn)確的定論。因此,本研究通過(guò)隨機(jī)分組對(duì)照試驗(yàn)探究抗阻力量訓(xùn)練干預(yù)能否改善體內(nèi)循環(huán)維生素D濃度,為健康指導(dǎo)者及衛(wèi)生工作者指導(dǎo)大眾改善體內(nèi)循環(huán)維生素D濃度的工作上提供科學(xué)依據(jù)。研究方法:本研究在上海市楊浦區(qū)(北緯31.27°)招募到18名健康成年男性(19～39歲),隨機(jī)分為運(yùn)動(dòng)組(9人,平均年齡24.4歲,平均BMI22.9kg/m2)與對(duì)照組(9人,平均年齡26.7歲,平均BMI22.4kg/m2)。運(yùn)動(dòng)組參與12周抗阻力量訓(xùn)練,每周3次,負(fù)荷強(qiáng)度為12-RM(repetitionmaximum),除此外,保持原有生活習(xí)慣;對(duì)照組不訓(xùn)練,且維持原有生活習(xí)慣。干預(yù)時(shí)期為2016年3月至6月,在實(shí)驗(yàn)干預(yù)的0周、第7周、第13周三個(gè)時(shí)間分別對(duì)受試者進(jìn)行空腹采血以及相關(guān)實(shí)驗(yàn)指標(biāo)的數(shù)據(jù)測(cè)量收集。血清中25羥基維生素D[25(OH)D]、甲狀旁腺激素(iPTH)和胰島素樣生長(zhǎng)因子1(IGF-1)濃度通過(guò)酶聯(lián)免疫測(cè)吸附測(cè)定法測(cè)得,中高強(qiáng)度身體活動(dòng)時(shí)間通過(guò)三軸加速度計(jì)ActigraphGT3X+測(cè)量,體脂率、肌肉質(zhì)量通過(guò)雙能X線骨密度儀測(cè)得,對(duì)應(yīng)抗阻力量訓(xùn)練項(xiàng)目的1-RM負(fù)荷強(qiáng)度通過(guò)Mayhew等的1-RM推算公式計(jì)算獲取。研究結(jié)果:運(yùn)動(dòng)組與對(duì)照組之間的基線各項(xiàng)指標(biāo)均無(wú)顯著性差異,且血清25(OH)D濃度均處于維生素D缺乏狀態(tài)(運(yùn)動(dòng)組:27.8±2.0nmol/L;對(duì)照組:26.2± 1.4nmol/L)。12周抗阻力量訓(xùn)練干預(yù)后,運(yùn)動(dòng)組與對(duì)照組受試者血清25(OH)D濃度均顯著升高,調(diào)整中高強(qiáng)度身體活動(dòng)、陽(yáng)光曝露及體脂率變化量的影響后,時(shí)間主效應(yīng)顯著(p=0.018),時(shí)間與分組交互作用具有統(tǒng)計(jì)學(xué)意義(p=0.026)�；�至第7周,運(yùn)動(dòng)組血清25(OH)D濃度沒(méi)有顯著變化(p=0.648),對(duì)照組顯著升高(p0.05),時(shí)間與分組交互作用顯著(p=0.026), 2組受試者血清iPTH、IGF-1濃度變化均沒(méi)有統(tǒng)計(jì)學(xué)意義,運(yùn)動(dòng)組肌肉質(zhì)量顯著升高(p=0.002),而對(duì)照組無(wú)顯著變化(p=1.0)。后6周,2組受試者血清25(OH)D濃度均顯著升高,調(diào)整3個(gè)混雜因素影響后,時(shí)間主效應(yīng)顯著(p=0.009),時(shí)間與分組的交互作用不具有統(tǒng)計(jì)學(xué)意義(p=0.274), 2組受試者血清iPTH濃度和肌肉質(zhì)量變化均沒(méi)有顯著性變化,運(yùn)動(dòng)組血清IGF-1濃度顯著下降(p=0.013),對(duì)照組沒(méi)有顯著變化(p=1.0),且在調(diào)整了年齡和中高強(qiáng)度身體活動(dòng)水平的影響后,時(shí)間與分組間的交互作用顯著(p=0.011)。運(yùn)動(dòng)組受試者在第7周,測(cè)試的5個(gè)抗阻力量訓(xùn)練項(xiàng)目中有3個(gè)1-RM顯著提高,在后6周,測(cè)試的5個(gè)抗阻力量訓(xùn)練項(xiàng)目的1-RM均顯著提高。結(jié)論:本研究發(fā)現(xiàn),12周的抗阻力量訓(xùn)練的初期減弱了維生素D缺乏的健康成年男性的血清25(OH)D濃度的上升趨勢(shì),而后期則沒(méi)有影響,建議抗阻力量訓(xùn)練在不同的訓(xùn)練階段對(duì)循環(huán)維生素D水平影響效果不同。
[Abstract]:Research purposes: the study shows that there is a positive correlation between physical activity and the concentration of vitamin D in the body, and it is found that the relationship still exists even if the effect of exposure to sunlight is excluded. However, most of the related studies are observation studies and can not reach the causal relationship between the two. The intervention study of the relationship between the D and the vegetarian relationship is not accurate because of the lack of experimental design. Therefore, this study explores whether the resistance to resistance strength training intervention can improve the concentration of vitamin D in the body through random group control trial, and the work of health instructors and health workers to guide the public to improve the concentration of vitamin D in the body. For scientific basis. Research methods: This study recruited 18 healthy adult males (19~39 years old) in Yangpu District, Shanghai (31.27 degrees north latitude). They were randomly divided into exercise group (9 people, average age 24.4 years, average BMI22.9kg/m2) and control group (9 people, average age 26.7 years, mean BMI22.4kg/m2). The exercise group was involved in 12 weeks resistance strength training, 3 times a week, load. The intensity was 12-RM (repetitionmaximum), in addition, in addition to maintaining the original living habits; the control group was not trained and maintained the original living habits. The intervention period was from March 2016 to June. The 0 weeks, seventh weeks, and thirteenth Wednesday of the experimental intervention were collected on the blood sampling and the data of the related experimental indexes respectively. The concentration of vitamin D[25 (OH) D], parathyroid hormone (iPTH) and insulin like growth factor 1 (IGF-1) was measured by enzyme linked immunosorbent assay. The medium high intensity physical activity time was measured by the three axis accelerometer ActigraphGT3X+, the body fat rate and the muscle mass were measured by the dual energy X-ray bone densitometer, corresponding to the 1-R of the resistance strength training project. M load intensity was calculated by the 1-RM calculation formula such as Mayhew. The results showed that there was no significant difference in baseline between the exercise group and the control group, and the concentration of serum 25 (OH) D was in the state of vitamin D deficiency (exercise group: 27.8 + 2.0nmol/L; the control group: 26.2 + 1.4nmol/L).12 week resistance strength training. The concentration of serum 25 (OH) D increased significantly in the subjects of the subjects. The time main effect was significant (p=0.018) and the interaction between time and group was statistically significant (p=0.026). The concentration of serum 25 (OH) D in the exercise group did not change significantly (p=0.648), and the control group was in the control group. Significantly increased (P0.05), time and group interaction significant (p=0.026), 2 groups of subjects serum iPTH, IGF-1 concentration changes were not statistically significant (p=0.002) in the exercise group (p=0.002), but the control group was not significantly changed (p=1.0). After the 6 week, the serum level of 25 (OH) D in the 2 groups was significantly increased, after the adjustment of 3 confounding factors, when the influence, when the influence, The interrelationship between the time and the group was not statistically significant (p=0.274). There was no significant change in serum iPTH concentration and muscle mass in the 2 groups. The serum IGF-1 concentration in the exercise group decreased significantly (p=0.013), the control group had no significant changes (p=1.0), and adjusted the age and moderate intensity of physical activity. The interaction between time and group was significant (p=0.011). In the seventh week of the 5 resistance strength training programs, 3 1-RM improved significantly in the exercise group. In the latter 6 weeks, the 1-RM of the 5 resistance strength training programs increased significantly. Conclusion: This study found that the initial 12 weeks of resistance strength training had weakened. The increase in serum 25 (OH) D concentration in healthy adult male patients with vitamin D deficiency has no effect at the later stage. It is suggested that the effect of resistance strength training on circulating vitamin D levels in different training stages is different.

【學(xué)位授予單位】：上海體育學(xué)院
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類號(hào)】：G804.2

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