兒童患者中分離189株卡他莫拉菌的分布和耐藥性分析
[Abstract]:Objective to study the clinical distribution and drug resistance of isolated strains of Morrah in children and to guide rational drug use. Methods the distribution, enzyme production and drug sensitivity of 189 strains of Mora carinii isolated from clinical samples of Beijing Children's Hospital from 2013 to 2014 were analyzed retrospectively. Drug sensitivity test was performed by disk diffusion method and 尾-lactamase was determined by ceftathiophene disk method. The results were judged according to the 2013 CLSI M45-A2 standard. Results the positive rate of 尾 lactamases was 95.70.The positive rate of amoxicillin clavulanic acid, trimethoprim sulfamethazol, amoxicillin, trimethoprim and sulfamethazol was 95.7%. The tetracycline resistance rates were 0.1% and 4.2%, respectively. The resistance rates of erythromycin and azithromycin were 82.5% and 83.1% respectively. Conclusion the positive rate of 尾 -lactamases carried by children patients is very high, and the characteristics of high enzyme production make penicillin drugs can not be used as a clinical first-line drug. Because of its high resistance to macrolides, it should be paid more attention in clinic and surveillance of drug resistance should be strengthened.
【作者單位】: 首都醫(yī)科大學(xué)附屬北京兒童醫(yī)院細(xì)菌室兒科學(xué)國(guó)家重點(diǎn)學(xué)科;
【分類(lèi)號(hào)】:R446.5
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