本文選題：人血白蛋白 + 綜合干預措施��； 參考：《中國藥房》2017年32期

【摘要】：目的:評價實施綜合干預措施對我院呼吸科人血白蛋白使用的影響,促進臨床合理用藥。方法:根據人血白蛋白說明書、相關指南及文獻,按照循證藥學方法建立我院呼吸科人血白蛋白使用評價標準,采取醫(yī)囑審核、處方點評、信息系統(tǒng)權限設置等技術措施和績效考核手段對人血白蛋白的使用進行綜合干預。調取2015年1-6月(干預前組,226例)、2016年1-6月(干預后組,148例)使用人血白蛋白的患者處方,對人血白蛋白總使用量、人均使用量、平均使用時間、適應證、禁忌證、合理性等進行統(tǒng)計分析,并比較干預前后兩組患者人血白蛋白的使用情況。結果:患者的人血白蛋白總使用量、人均使用量、平均使用時間分別由干預前的18 350 g、(81.2±71.3)g、(7.8±7.2)d,下降至干預后的7 584 g、(51.2±48.3)g、(4.7±2.1)d;患者使用人血白蛋白不符合《人血白蛋白、非蛋白膠體溶液及晶體溶液使用指南》規(guī)定的適應證比例、違背禁忌證使用人血白蛋白的比例分別由干預前的80.1%、50.0%下降至干預后的39.9%、16.9%;用藥前血清白蛋白濃度≥35 g/L、≥30~35 g/L、≥20~25 g/L組患者人數(shù)干預前組明顯多于干預后組,20 g/L、≥20~25 g/L組患者人數(shù)干預后組明顯多于干預前;合理使用人血白蛋白的患者比例由干預前的16.8%上升至干預后的52.7%,以上指標干預前后比較,差異均有統(tǒng)計學意義(P0.05)。結論:綜合干預措施可有效降低人血白蛋白在適應證、療程等方面的不合理使用及比例等,提高臨床合理使用水平。
[Abstract]:Objective: to evaluate the effect of comprehensive intervention on the use of human serum albumin (HSA) in respiratory department. Methods: according to the instruction of human serum albumin (HSA), the related guidelines and literatures, and according to the method of evidence-based pharmacology, the evaluation standard of human serum albumin in respiratory department of our hospital was established, and the doctors' orders were examined and the prescriptions were evaluated. Technical measures, such as information system authority setting and performance evaluation, were used to comprehensively intervene in the use of human serum albumin (HSA). From January to June 2015 (226 patients in the pre-intervention group and 148 patients in the post-intervention group), the total usage of human serum albumin, average usage per capita, average time of use, indications, contraindications and contraindications were obtained. The rationality was statistically analyzed and the use of human serum albumin was compared between the two groups before and after intervention. Results: the total usage of human serum albumin, the per capita usage, and the average time of use were decreased from 81.2 鹵71.3 g / d before intervention to 7 584 g / L 51.2 鹵48.3 g / d after intervention and 4.7 鹵2.1 / d after intervention, respectively, and the mean time of using human serum albumin was not in accordance with < human serum albumin (HSA). The proportion of indications specified in the guidelines for the use of nonprotein colloidal solutions and crystal solutions, The proportion of using human serum albumin before intervention decreased from 80.1% to 39.9% after intervention, and the concentration of serum albumin was more than 35 g / L, 鈮，

本文編號：1870385