目的自體血液穴位注射在臨床用于多種各種疾病,但是該療法影響人體的機(jī)制尚不清楚。本研究旨在觀察穴位注射血液后穴位區(qū)域的組織學(xué)變化。方法在小鼠左側(cè)足三里（ST-36）穴位處注射從同種小鼠收集的血液0.1 m L。注射后0、6、12、24、48、72和96 h（每個(gè)時(shí)間點(diǎn)3只小鼠）,收集外周血和注射部位的肌肉組織用于血細(xì)胞分類和組織學(xué)研究（HE染色）。結(jié)果穴位注射治療后,小鼠外周血白細(xì)胞、淋巴細(xì)胞和血小板呈一定增加趨勢。注射24 h后,穴位注射部位表現(xiàn)為急性炎癥反應(yīng),注射的血液成分主要被中性粒細(xì)胞浸潤,并觀察到少量單核細(xì)胞,而紅細(xì)胞則逐漸消失。注射后24～96 h,穴位主要表現(xiàn)為慢性炎癥反應(yīng),單核細(xì)胞、巨噬細(xì)胞、淋巴細(xì)胞、成纖維細(xì)胞浸潤逐漸增加;中性粒細(xì)胞逐漸減少,局部肌纖維被破壞,纖維組織增生。結(jié)論注射到穴位的血液模擬肌肉組織中血腫的吸收過程,引發(fā)局部炎癥反應(yīng)以吞噬并清除血液成分,這可能是刺激穴位產(chǎn)生相關(guān)治療效應(yīng)的基礎(chǔ)。 

【文章來源】：南方醫(yī)科大學(xué)學(xué)報(bào). 2020,40(09)北大核心CSCD

【文章頁數(shù)】：5 頁

【文章目錄】：
INTRODUCTION
METHODS
    Animal grouping
    Peripheral blood classification
    Histological study
RESULTS
    Peripheral blood classification
    Histological study
DISCUSSION


【參考文獻(xiàn)】：
期刊論文
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[2]Heat-sensitive moxibustion for lumbar disc herniation:a meta-analysis of randomized controlled trials[J]. Rixin Chen,Jun Xiong,Zhenhai Chi,Bo Zhang,Acupuncture and Rehabilitation Department,The Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine,Nanchang 330006,China;Key Laboratory of Heat-sensitive Moxibustion,State Administration of Traditional Chinese Medicine of People’s Republic of China,Nanchang 330006,China;Acupoint Sensibility Laboratory,State Administration of Traditional Chinese Medicine of People’s Republic of China,Nanchang 330006,China.  Journal of Traditional Chinese Medicine. 2012(03)



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