【摘要】：目的：初步探討幽門螺桿菌相關(guān)性消化性潰瘍的中醫(yī)證候分布規(guī)律、HP與中醫(yī)證候的相關(guān)性等,從而為中醫(yī)藥臨床規(guī)范有效治療本病提供一定臨床依據(jù)。方法：選取符合標準的患者病例共200例,根據(jù)患者一般資料建立數(shù)據(jù)庫,應(yīng)用頻數(shù)分析分析患者一般資料,系統(tǒng)聚類分析法歸納出中醫(yī)證型,頻數(shù)分析及卡方檢驗分析中醫(yī)證型分布情況,結(jié)合專業(yè)知識分析幽門螺桿菌相關(guān)性消化性潰瘍的證候分布情況,并初步探討其證型分布規(guī)律。結(jié)果：本研究隨機200例患者病例資料男性多于女性,青年組和中年組所占比例均等且較大、老年組較��；吸煙、飲灑、藥物、飲食、情緒均為重要的發(fā)病因素；十二指腸潰瘍多于胃潰瘍,復合性潰瘍最少；潰瘍活動期攝多,愈合期次之,瘢痕期最少：200例患者中潰瘍再發(fā)人數(shù)所占比例較大。系統(tǒng)聚類得出證候分布頻數(shù)依次為：肝氣犯胃證(29.5%)胃陰不足證(20.5%)脾胃虛寒證(19%)脾胃濕熱證(12%)胃絡(luò)瘀阻證(9.5%)和脾胃氣虛證(9.5%)。各個證型年齡段的分布結(jié)果差異具有統(tǒng)計學意義(P=0.030.05)。結(jié)論：1.Hp相關(guān)性消化性潰瘍患者以中年、男性多見；部位以十二指腸潰瘍多見：分期以活動期多見；吸煙、飲酒、飲食、心理與情緒、阿司匹林等因素對潰瘍的發(fā)病不可忽視。2.通過系統(tǒng)聚類方法總結(jié)出臨床上6個中醫(yī)證型,依照頻數(shù)分布依次為肝氣犯胃證、胃陰不足證、脾胃虛寒證、脾胃濕熱證、胃絡(luò)瘀阻證和脾胃氣虛證。3.肝氣犯胃證、脾胃濕熱證主要見于青、中年患者,胃陰不足證、胃絡(luò)瘀阻證多見于中、老年患者,脾胃虛寒證及脾胃氣虛證反而青年患者多見；幽門螺桿菌相關(guān)性消化性潰瘍患者男性各個證型均多于女性,且無論男女皆以肝氣犯胃證多見。4.胃潰瘍及十二指腸潰瘍屬肝氣犯胃者最多,復合性潰瘍證型屬胃陰不足者最多,雖然潰瘍部位不同但均可見各證型。5.消化性潰瘍的復發(fā)與Hp感染密切相關(guān),中醫(yī)藥在根除Hp、降低潰瘍復發(fā)率、促進潰瘍愈合質(zhì)量(Quality of ulcer Healing, QOUH)等方面具有一定的優(yōu)勢。
[Abstract]:Objective: to investigate the distribution of TCM syndromes and the correlation between HP and TCM syndromes of HP-associated peptic ulcer, so as to provide some clinical basis for the effective treatment of HP-associated peptic ulcer. Methods: a total of 200 patients were selected to establish a database according to the general data of the patients. The general data of the patients were analyzed by frequency analysis, and the TCM syndrome types were summarized by systematic cluster analysis. Frequency analysis and chi-square test were used to analyze the distribution of TCM syndrome types, combined with professional knowledge, the syndrome distribution of HP-associated peptic ulcer was analyzed, and the distribution law of syndrome types was discussed. Results: the data of 200 patients in this study were more in males than in females. The proportion of young group and middle-aged group was equal and larger, but the elderly group was smaller. Smoking, drinking, medicine, diet and emotion were important factors. Duodenal ulcer was more than gastric ulcer, compound ulcer was the least, ulcer active stage was more, healing stage was the second, scar stage was the least: 200 cases of ulcer recurrence accounted for a large proportion. The distribution frequency of syndrome was as follows: liver qi invading stomach syndrome (29.5%), stomach yin deficiency syndrome (20.5%), spleen and stomach deficiency cold syndrome (19%), spleen and stomach dampness and heat syndrome (12%), gastric collateral stasis syndrome (9.5%) and spleen and stomach stasis syndrome (9.5%). Qi deficiency syndrome (9.5%). There was significant difference in the distribution results of each syndrome age group (P 鈮，

本文編號：2491825