【摘要】：目的:觀察采用乳癖消片治療乳腺增生癥的臨床療效,并分析可能的療效機(jī)制,以期為該病的臨床診療提供參考。方法:分析2013年1月至2016年1月在某院接受診療的乳腺增生癥患者的臨床資料。依據(jù)不同的治療方案分為觀察組(乳癖消片+依西美坦)及對照組(依西美坦)。治療8周后對比2組的臨床療效并分析可能的療效機(jī)制。結(jié)果:本研究共納入觀察組42例,對照組45例。觀察組患者治療有效率顯著高于對照組(78.6%vs.57.8%;χ2=4.304,P=0.038)。治療后2組患者黃體生成素及孕酮水平均顯著升高(P0.05),但觀察組顯著高于對照組(P0.05);治療后2組患者雌二醇及催乳素水平均顯著降低(P0.05),但觀察組顯著低于對照組患者水平(P0.05);治療后2組患者C-反應(yīng)蛋白(CRP)及白介素-6(IL-6)水平均顯著降低(P0.05),但觀察組顯著低于對照組(P0.05)。結(jié)論:輔助使用乳癖消片治療乳腺增生癥可顯著提高療效,可能與其調(diào)節(jié)內(nèi)分泌紊亂及抑制炎癥反應(yīng)有關(guān)。
[Abstract]:Objective: to observe the clinical efficacy of Rupixiao tablets in the treatment of breast hyperplasia and to analyze the possible therapeutic mechanism in order to provide reference for the clinical diagnosis and treatment of the disease. Methods: the clinical data of breast hyperplasia patients diagnosed and treated in a hospital from January 2013 to January 2016 were analyzed. According to different treatment schemes, they were divided into observation group (Rupixiao tablet Isimetam) and control group (Isimetam). After 8 weeks of treatment, the clinical efficacy of the two groups was compared and the possible therapeutic mechanism was analyzed. Results: a total of 42 cases in the observation group and 45 cases in the control group were included in this study. The effective rate of treatment in the observation group was significantly higher than that in the control group (78.6% vs. 57.8%; 蠂 2 鈮，

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