50例原發(fā)性腎癌患者中醫(yī)用藥規(guī)律的臨床研究
發(fā)布時間：2019-05-13 23:31
【摘要】：目的:分析原發(fā)性腎癌患者在不同疾病階段的治療情況,觀察中醫(yī)藥在參與原發(fā)性腎癌患者治療中的應用情況,研究原發(fā)性腎癌的中醫(yī)用藥規(guī)律,為臨床治療本病提供有價值的參考。資料與方法:回顧性收集在2013年3月一2016年2月于遼寧中醫(yī)藥大學附屬醫(yī)院腫瘤科住院的以原發(fā)性腎癌為第一診斷的患者的資料,選取其中符合條件的病例,用Microsoft Excel軟件建立數據庫,分別統計患者西醫(yī)的對癥治療方法、中成藥數量的應用情況、具有抗癌作用的中藥應用數量情況、中藥方劑的具體應用情況,中藥藥物分類和藥味。結果:1.原發(fā)性腎癌患者的一般資料:此次統計共有原發(fā)性腎癌患者50例,其中男性32例、女性18例;年齡最小33歲,最大91歲,平均年齡(68.21±10.28);早期8例、中期17例、晚期16例、終末期9例;肺轉移17例、骨轉移12例、肝轉移6例、淋巴結轉移4例、腹膜轉移4例、乳腺轉移1例、膀胱轉移1例;行手術治療者24例、行靶向治療者18例、行生物免疫治療者23例。2.原發(fā)性腎癌患者西醫(yī)的對癥治療方法:在早期,以提高免疫力治療和抗炎治療為主,在中期,以提高免疫力治療和骨保護治療為主,在晚期,以提高免疫力治療和抗炎治療為主,在前三期提高免疫力均是最主要的治療;在終末期,以營養(yǎng)治療和抗炎治療為主。3.中成藥的具體應用情況:在早期應用最多的中成藥是:抗癌類中成藥;在中期應用最多的中成藥是:抗癌類中成藥,晚期應用最多的中成藥是:扶正類中成藥;終末期應用最多的中成藥是:扶正類中成藥。4.原發(fā)性腎癌患者具有作用抗癌的中藥應用數量的情況:在早期3~5味抗癌中藥應用最多,共有5例,在中期6~8味抗癌中藥應用最多,共有9例,在晚期1~2味抗癌中藥應用最多,共有9例,在終末期不應用具有抗癌作用的中藥。5.在早期:六味地黃湯合柴胡龍骨牡蠣湯加減應用最多;在中期:六味地黃湯合柴胡龍骨牡蠣湯加減應用最多;在晚期:六味地黃湯合四君子湯加減應用最多。6.在治療原發(fā)性腎癌的過程中,中藥藥物分類中補虛藥應用最多,其次是利水滲濕藥和清熱藥,三者的比例超過了50%,藥味以甘,苦,辛為主,甘味占絕對優(yōu)勢。結論:1.在原發(fā)性腎癌患者治療的過程中,六味地黃湯應用最多;中藥藥物分類中補虛藥、利水滲濕藥和清熱藥應用最多;藥味以甘、苦、辛所占比例最多。2.早期中醫(yī)治療以減輕手術反應及對癥治療,以促進術后中氣的恢復、預防腫瘤的復發(fā)轉移為主要的治療思路。3.中期中醫(yī)治療以抗癌為主,扶正為輔為主要的治療思路。4.晚期中醫(yī)治療以扶正為主,抗癌為輔為主要的治療思路。5.終末期中醫(yī)治療以扶正和對癥治療為主要的治療思路。
[Abstract]:Objective: to analyze the treatment of primary renal cell carcinoma (RCC) in different stages, to observe the application of traditional Chinese medicine (TCM) in the treatment of primary renal cell carcinoma (RCC), and to study the regularity of TCM medication in PRCC. It provides valuable reference for clinical treatment of this disease. Materials and methods: the data of primary renal cell carcinoma hospitalized in the Department of Oncology, affiliated Hospital of Liaoning University of traditional Chinese Medicine from March 2013 to February 2016 were collected retrospectively. the eligible cases were selected. The database was established by Microsoft Excel software to count the symptomatic treatment of patients with western medicine, the application of proprietary Chinese medicine, the quantity of traditional Chinese medicine with anticancer effect, the specific application of traditional Chinese medicine prescription, the classification and taste of traditional Chinese medicine. Result: 1. General data of patients with primary renal carcinoma: there were 50 patients with primary renal cancer, including 32 males and 18 females, the youngest was 33 years old, the oldest was 91 years old, and the average age was 68.21 鹵10.28). There were 8 cases of early, 17 cases of middle stage, 16 cases of late stage, 9 cases of end stage, 17 cases of lung metastasis, 12 cases of bone metastasis, 6 cases of liver metastasis, 4 cases of lymph node metastasis, 4 cases of peritoneal metastasis, 1 case of breast metastasis and 1 case of bladder metastasis. 24 cases were treated surgically, 18 cases were treated with targeted therapy, and 23 cases were treated with bioimmunotherapy. Symptomatic treatment of patients with primary renal cancer: in the early stage, mainly to improve immunity therapy and anti-inflammatory treatment, in the middle stage, to improve immunity therapy and bone protection treatment, in the late stage, In order to improve immunity therapy and anti-inflammatory treatment, improving immunity in the first three stages is the most important treatment. At the end-stage, nutritional therapy and anti-inflammatory therapy were the main treatments. The specific application of proprietary Chinese medicine: the most widely used proprietary Chinese medicine in the early stage is: anticancer proprietary Chinese medicine, the most widely used Chinese patent medicine in the middle stage is: anticancer proprietary Chinese medicine, the most widely used traditional Chinese patent medicine in the late stage is: Fuzheng proprietary Chinese patent medicine; The most commonly used proprietary Chinese medicine in the end-stage is Fuzheng proprietary Chinese medicine. 4. The number of traditional Chinese medicine with anticancer effect in patients with primary renal cancer: in the early stage, 5 cases were used, 6 cases were used in the middle stage, 9 cases were used in the middle stage, and the most were used in the late stage of 1 and 2 kinds of anticancer traditional Chinese medicine, which were the most widely used in the early stage of 3 kinds of anticancer traditional Chinese medicine, 5 cases in the middle stage, 9 cases in the middle stage. A total of 9 cases, in the end-stage of the use of traditional Chinese medicine with anticancer effect. 5. In the early stage: Liuwei Dihuang decoction Hechaihu Dragon Bone Oyster soup was the most widely used; in the middle stage: Liuwei Dihuang decoction and Bupleurum keel Oyster soup was the most widely used; in the late stage: Liuwei Dihuang decoction and Sijunzi decoction were the most widely used. 6. In the process of treating primary renal cell carcinoma, tonifying deficiency drugs were the most widely used in the classification of traditional Chinese medicine, followed by dampness drugs and antipyretic drugs, the proportion of which was more than 50%. The taste of drugs was mainly sweet, bitter and Xin, and sweet flavor was the absolute advantage. Conclusion: 1. Liuwei Dihuang decoction is the most widely used in the treatment of patients with primary renal cell carcinoma. In the classification of traditional Chinese medicine, tonifying deficiency drugs, promoting dampness drugs and clearing away heat drugs are the most used, and the proportion of sweet, bitter and Xin is the most. 2. (2) in the process of treatment of patients with primary renal cancer, Liuwei Dihuang decoction is the most widely used in the classification of traditional Chinese medicine. The main treatment idea of early traditional Chinese medicine treatment is to reduce the surgical reaction and symptomatic treatment, to promote the recovery of qi after operation, and to prevent the recurrence and metastasis of tumor. 3. The main treatment idea of middle stage traditional Chinese medicine is anticancer, Fuzheng as auxiliary. 4. The treatment of advanced traditional Chinese medicine is mainly Fuzheng, supplemented by anticancer. 5. The main treatment idea of end-stage traditional Chinese medicine is Fuzheng and symptomatic treatment.
【學位授予單位】：遼寧中醫(yī)藥大學
【學位級別】：碩士
【學位授予年份】：2017
【分類號】：R273
本文編號：2476263
[Abstract]:Objective: to analyze the treatment of primary renal cell carcinoma (RCC) in different stages, to observe the application of traditional Chinese medicine (TCM) in the treatment of primary renal cell carcinoma (RCC), and to study the regularity of TCM medication in PRCC. It provides valuable reference for clinical treatment of this disease. Materials and methods: the data of primary renal cell carcinoma hospitalized in the Department of Oncology, affiliated Hospital of Liaoning University of traditional Chinese Medicine from March 2013 to February 2016 were collected retrospectively. the eligible cases were selected. The database was established by Microsoft Excel software to count the symptomatic treatment of patients with western medicine, the application of proprietary Chinese medicine, the quantity of traditional Chinese medicine with anticancer effect, the specific application of traditional Chinese medicine prescription, the classification and taste of traditional Chinese medicine. Result: 1. General data of patients with primary renal carcinoma: there were 50 patients with primary renal cancer, including 32 males and 18 females, the youngest was 33 years old, the oldest was 91 years old, and the average age was 68.21 鹵10.28). There were 8 cases of early, 17 cases of middle stage, 16 cases of late stage, 9 cases of end stage, 17 cases of lung metastasis, 12 cases of bone metastasis, 6 cases of liver metastasis, 4 cases of lymph node metastasis, 4 cases of peritoneal metastasis, 1 case of breast metastasis and 1 case of bladder metastasis. 24 cases were treated surgically, 18 cases were treated with targeted therapy, and 23 cases were treated with bioimmunotherapy. Symptomatic treatment of patients with primary renal cancer: in the early stage, mainly to improve immunity therapy and anti-inflammatory treatment, in the middle stage, to improve immunity therapy and bone protection treatment, in the late stage, In order to improve immunity therapy and anti-inflammatory treatment, improving immunity in the first three stages is the most important treatment. At the end-stage, nutritional therapy and anti-inflammatory therapy were the main treatments. The specific application of proprietary Chinese medicine: the most widely used proprietary Chinese medicine in the early stage is: anticancer proprietary Chinese medicine, the most widely used Chinese patent medicine in the middle stage is: anticancer proprietary Chinese medicine, the most widely used traditional Chinese patent medicine in the late stage is: Fuzheng proprietary Chinese patent medicine; The most commonly used proprietary Chinese medicine in the end-stage is Fuzheng proprietary Chinese medicine. 4. The number of traditional Chinese medicine with anticancer effect in patients with primary renal cancer: in the early stage, 5 cases were used, 6 cases were used in the middle stage, 9 cases were used in the middle stage, and the most were used in the late stage of 1 and 2 kinds of anticancer traditional Chinese medicine, which were the most widely used in the early stage of 3 kinds of anticancer traditional Chinese medicine, 5 cases in the middle stage, 9 cases in the middle stage. A total of 9 cases, in the end-stage of the use of traditional Chinese medicine with anticancer effect. 5. In the early stage: Liuwei Dihuang decoction Hechaihu Dragon Bone Oyster soup was the most widely used; in the middle stage: Liuwei Dihuang decoction and Bupleurum keel Oyster soup was the most widely used; in the late stage: Liuwei Dihuang decoction and Sijunzi decoction were the most widely used. 6. In the process of treating primary renal cell carcinoma, tonifying deficiency drugs were the most widely used in the classification of traditional Chinese medicine, followed by dampness drugs and antipyretic drugs, the proportion of which was more than 50%. The taste of drugs was mainly sweet, bitter and Xin, and sweet flavor was the absolute advantage. Conclusion: 1. Liuwei Dihuang decoction is the most widely used in the treatment of patients with primary renal cell carcinoma. In the classification of traditional Chinese medicine, tonifying deficiency drugs, promoting dampness drugs and clearing away heat drugs are the most used, and the proportion of sweet, bitter and Xin is the most. 2. (2) in the process of treatment of patients with primary renal cancer, Liuwei Dihuang decoction is the most widely used in the classification of traditional Chinese medicine. The main treatment idea of early traditional Chinese medicine treatment is to reduce the surgical reaction and symptomatic treatment, to promote the recovery of qi after operation, and to prevent the recurrence and metastasis of tumor. 3. The main treatment idea of middle stage traditional Chinese medicine is anticancer, Fuzheng as auxiliary. 4. The treatment of advanced traditional Chinese medicine is mainly Fuzheng, supplemented by anticancer. 5. The main treatment idea of end-stage traditional Chinese medicine is Fuzheng and symptomatic treatment.
【學位授予單位】：遼寧中醫(yī)藥大學
【學位級別】：碩士
【學位授予年份】：2017
【分類號】：R273
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