壯、漢民族高血壓患者中醫(yī)證型分布及相關(guān)因素研究
發(fā)布時(shí)間：2019-05-11 04:07
【摘要】：目的:探討壯、漢民族高血壓患者中醫(yī)證型分布及相關(guān)因素研究,為壯、漢民族高血壓病患者中醫(yī)辨證客觀化和防治規(guī)范化提供科學(xué)依據(jù)。方法:設(shè)計(jì)調(diào)查登記表收集壯、漢族已確診為原發(fā)性高血壓患者644例,其中壯族343例,漢族301例,系統(tǒng)回顧其中醫(yī)四診信息,生化指標(biāo)、危險(xiǎn)因素等,進(jìn)行中醫(yī)辨證分型,并建立數(shù)據(jù)庫(kù),采用SPSS19.0統(tǒng)計(jì)軟件,分析壯族與漢族高血壓病中醫(yī)證型分布情況,壯族與漢族不同性別、年齡段高血壓病中醫(yī)證型分布情況,壯族與漢族高血壓患者一般情況與血生化指標(biāo)對(duì)比分析,壯族與漢族高血壓患者不同中醫(yī)證型血生化指標(biāo)比較,壯族與漢族高血壓患者中醫(yī)證候積分分級(jí)情況及中醫(yī)證型與證候積分的分布情況。結(jié)果:(1)壯族高血壓病中醫(yī)證型分布情況為:痰濕壅盛(41.12%),陰虛陽(yáng)亢(32.65%),陰陽(yáng)兩虛(18.07%),肝火亢盛(8.16%);漢族高血壓病中醫(yī)證型分布情況為:痰濕壅盛(52.49%),陰虛陽(yáng)亢(21.97%),陰陽(yáng)兩虛(16.24%),肝火亢盛(9.30%),兩民族高血壓中醫(yī)證型在肝火亢盛和陰陽(yáng)兩虛型差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。壯族與漢族高血壓患者在痰濕壅盛、陰虛陽(yáng)亢證型分布比例差異具有明顯統(tǒng)計(jì)學(xué)意義(P0.01);(2)壯族男性與女性高血壓中醫(yī)證型、漢族男性與女性高血壓中醫(yī)證型分布、壯族與漢族男性中醫(yī)證型分布比較差異均無(wú)統(tǒng)計(jì)學(xué)意義(P0.05),壯族與漢族女性中醫(yī)證型分布差異具有統(tǒng)計(jì)學(xué)意義(p0.05);(3)壯族高血壓中醫(yī)證型、漢族高血壓中醫(yī)證型在不同年齡段分布差異均具有統(tǒng)計(jì)學(xué)意義(p0.05);(4)壯族與漢族高血壓患者發(fā)病年齡、飲酒史、心血管家族史、空腹血糖比較差異均無(wú)統(tǒng)計(jì)學(xué)意義(p0.05),壯族與漢族高血壓患者血ua、cr、tc、tg、ldl-c、hdl-c比較差異均具有統(tǒng)計(jì)學(xué)意義(p0.05);(5)壯族高血壓患者不同中醫(yī)證型血生化指標(biāo)比較,與肝火亢盛型比較,痰濕壅盛與陰虛陽(yáng)亢型血ua具有差異性(p0.01,p0.05);與痰濕壅盛型比較,陰虛陽(yáng)亢與陰陽(yáng)兩虛型血ua具有差異性(p0.01,p0.05);與陰虛陽(yáng)亢型比較,陰陽(yáng)兩虛型血ua具有差異性(p0.05)。與肝火亢盛型比較,痰濕壅盛血cr具有差異性(p0.05);與痰濕壅盛型比較,陰虛陽(yáng)亢與陰陽(yáng)兩虛型血cr具有差異性(p0.05)。與肝火亢盛型比較,陰虛陽(yáng)亢型tc、ldl-c、hdl-c均具有差異性(p0.05)。與肝火亢盛型比較,陰虛陽(yáng)亢與陰陽(yáng)兩虛型fbs均具有差異性(p0.05)。漢族高血壓患者不同中醫(yī)證型血生化指標(biāo)比較,與肝火亢盛型比較,陰虛陽(yáng)亢與陰陽(yáng)兩虛型血ua具有明顯差異(p0.01);與痰濕壅盛型比較,陰虛陽(yáng)亢與陰陽(yáng)兩虛型血ua具有明顯差異(p0.01)。與肝火亢盛型比較,痰濕壅盛型血cr具有差異性(p0.05);與痰濕壅盛型比較,陰虛陽(yáng)亢與陰陽(yáng)兩虛型血cr具有差異性(p0.05);(6)壯族與漢族高血壓患者中醫(yī)證候積分等級(jí)分布差異無(wú)統(tǒng)計(jì)學(xué)意義(p0.05);(7)壯族高血壓患者中醫(yī)證型與證候積分分級(jí)分布情況,肝火亢盛型主要表現(xiàn)為中醫(yī)證候積分的中型,痰濕壅盛型、陰虛陽(yáng)亢型主要表現(xiàn)為中醫(yī)證候積分的中、重型,陰陽(yáng)兩虛型主要表現(xiàn)為中醫(yī)證候積分的重型;漢族高血壓患者中醫(yī)證型與證候積分分級(jí)分布情況,肝火亢盛型、痰濕壅盛型、陰虛陽(yáng)亢型主要表現(xiàn)為中醫(yī)證候積分的中型,陰陽(yáng)兩虛型主要表現(xiàn)為中醫(yī)證候積分的重型;壯族與漢族高血壓患者各中醫(yī)證型與證候積分分級(jí)分布差異均無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論:(1)壯族與漢族高血壓患者在痰濕壅盛、陰虛陽(yáng)亢證型分布比例具有差異性,壯族與漢族高血壓中醫(yī)證型在性別分布差異不明顯。(2)壯族與漢族高血壓中醫(yī)證型在不同年齡段分布均有一定差異性,這種中醫(yī)證型年齡分布差異性可能與中醫(yī)病因病機(jī)的演變有關(guān)。(3)壯族與漢族高血壓患者心血管一般情況(BMI、吸煙史)及血生化指標(biāo)有一定的差異性。(4)壯族與漢族高血壓患者中醫(yī)證型與部分血生化指標(biāo)均具有差異性,表明中醫(yī)證型與現(xiàn)代實(shí)驗(yàn)室指標(biāo)具有一定的相關(guān)性。(5)壯族與漢族高血壓患者中醫(yī)證候積分分級(jí)分布無(wú)明顯差異性。
[Abstract]:Objective: To study the distribution of TCM syndrome and related factors in Zhuang and Han nationality patients with hypertension, and to provide scientific basis for the objective and standardization of TCM syndrome differentiation in Chinese and Chinese patients with hypertension. Methods: There were 644 cases of primary hypertension, including 343 cases of Zhuang nationality and 301 cases of Han nationality, in which 343 cases of Zhuang nationality and 301 cases of Han nationality were diagnosed as essential hypertension. The TCM syndrome differentiation was carried out, and the database was established and the software of SPSS19.0 was used. To analyze the distribution of TCM syndrome types in Zhuang and Han patients, and to analyze the distribution of TCM syndrome type in the Zhuang and Han nationality, the general situation of the Zhuang and Han patients with hypertension, and the comparative analysis of the blood biochemical indexes. The classification of TCM syndrome and the distribution of TCM syndrome and syndrome were compared between Zhuang and Han patients with hypertension. Results: (1) The distribution of TCM syndrome type in Zhuang nationality was as follows: the phlegm and dampness, the yin deficiency (32.65%), the yin and yang deficiency (18.07%) and the liver fire hyperactivity (8.16%), and the distribution of the syndrome type of the Chinese traditional Chinese medicine in the Han nationality was: the phlegm and dampness (52.49%). The yin and yang deficiency (21.97%), the yin and yang deficiency (16.24%) and the liver-fire hyperactivity (9.30%) were not significant (P0.05). There was a significant difference in the distribution proportion of the Han nationality and the Han nationality in the Han nationality (P 0.01), (2) the distribution of the Chinese traditional Chinese medicine syndrome type, the Han nationality and the female high blood pressure TCM syndrome type in the Zhuang nationality and the female hypertension. There was no significant difference in the distribution of TCM syndrome types between Zhuang and Han Chinese (P0.05). There was a significant difference in the distribution of TCM syndromes among Zhuang and Han women (p0.05), (3) the TCM syndrome of Zhuang nationality, (4) The age, history of drinking, family history of cardiovascular and fasting blood glucose were not significant (p0.05). The differences of blood ua, cr, tc, tg, ldl-c and hdl-c in the Zhuang and Han patients with hypertension were of statistical significance (p0.05); (5) The blood biochemical indexes of different TCM syndromes in Zhuang nationality were compared with those of the liver-fire type. There was a difference (p0.01, p0.05) between the deficiency of the yin and the yang, and the difference between the yin deficiency of the yin and the yin and yang (p0.01, p0.05), and the difference between the yin and yang deficiency type of the blood (p0.05). Compared with the hyperactive type of the liver fire, the blood cr of the phlegm-wet type was different (p0.05), and the difference between the yin deficiency and the yin-yang and the yin-yang deficiency-type blood cr (p0.05) was compared with that of the phlegm-dampness type. Compared with the liver-fire type, the type of yin-deficiency-yang-type tc, ldl-c, and hdl-c had a difference (p0.05). Compared with the liver-fire type, both the yin deficiency and the yin-yang deficiency and the yin-yang deficiency type fbs have the difference (p0.05). There was a significant difference between yin deficiency and yin-yang and yin-yang deficiency type blood (p0.01), compared with the blood biochemical index of the type of liver-fire, the yin-deficiency-yang-hyperactivity, and the yin-yang deficiency type of the blood-ua (p0.01), compared with the blood biochemical indexes of the patients with high blood pressure in the Han nationality. Compared with the liver-fire type, the blood cr of the phlegm-dampness type was different (p0.05), and the difference between the yin deficiency and the yin-yang and the yin-yang deficiency-type blood cr (p0.05) and the difference of the distribution of the integral grade of the traditional Chinese medicine syndrome in the Zhuang and Han-Han patients (p0.05). (7) The distribution of TCM syndrome types and syndrome points in Zhuang nationality patients with high blood pressure is mainly manifested as medium-sized, phlegm-dampness and high-type, and the yin-deficiency-yang hyperactive type mainly manifested as the middle and heavy-duty of the TCM syndrome integration. The yin-yang and yin-deficiency type mainly manifested as the heavy-duty of the syndrome of the traditional Chinese medicine; the classification and distribution of the TCM syndrome type and the syndrome integration of the Han-type hypertension patients, the hyperactivity of the liver-fire type, the phlegm-dampness type and the yin-deficiency-yang type are the middle-and medium-sized with the integral of the syndrome of the Chinese medicine, The two-deficiency type of Yin and Yang is the heavy-duty of TCM syndrome, and there is no significant difference in the distribution of TCM syndrome type and syndrome integration in the Zhuang and Han patients (P0.05). Conclusion: (1) The distribution ratio of Chinese traditional Chinese medicine syndrome of Zhuang and Han is different, and the difference between Zhuang and Han type of hypertension is not obvious in the distribution of sex distribution. (2) There is a certain difference in the distribution of Chinese traditional Chinese medicine syndrome of Zhuang and Han nationality in different age groups, which may be related to the evolution of the etiology and pathogenesis of the traditional Chinese medicine. (3) There was some difference in the general condition of cardiovascular disease (BMI, smoking history) and blood biochemical index in Zhuang and Han patients with hypertension. (4) The TCM syndrome type and some blood biochemical indexes of the Zhuang and Han patients with hypertension have a difference, indicating that the TCM syndrome type has a certain correlation with the modern laboratory index. (5) There was no significant difference in the distribution of TCM syndrome in Zhuang and Han patients.
【學(xué)位授予單位】：廣西中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類(lèi)號(hào)】：R259
[Abstract]:Objective: To study the distribution of TCM syndrome and related factors in Zhuang and Han nationality patients with hypertension, and to provide scientific basis for the objective and standardization of TCM syndrome differentiation in Chinese and Chinese patients with hypertension. Methods: There were 644 cases of primary hypertension, including 343 cases of Zhuang nationality and 301 cases of Han nationality, in which 343 cases of Zhuang nationality and 301 cases of Han nationality were diagnosed as essential hypertension. The TCM syndrome differentiation was carried out, and the database was established and the software of SPSS19.0 was used. To analyze the distribution of TCM syndrome types in Zhuang and Han patients, and to analyze the distribution of TCM syndrome type in the Zhuang and Han nationality, the general situation of the Zhuang and Han patients with hypertension, and the comparative analysis of the blood biochemical indexes. The classification of TCM syndrome and the distribution of TCM syndrome and syndrome were compared between Zhuang and Han patients with hypertension. Results: (1) The distribution of TCM syndrome type in Zhuang nationality was as follows: the phlegm and dampness, the yin deficiency (32.65%), the yin and yang deficiency (18.07%) and the liver fire hyperactivity (8.16%), and the distribution of the syndrome type of the Chinese traditional Chinese medicine in the Han nationality was: the phlegm and dampness (52.49%). The yin and yang deficiency (21.97%), the yin and yang deficiency (16.24%) and the liver-fire hyperactivity (9.30%) were not significant (P0.05). There was a significant difference in the distribution proportion of the Han nationality and the Han nationality in the Han nationality (P 0.01), (2) the distribution of the Chinese traditional Chinese medicine syndrome type, the Han nationality and the female high blood pressure TCM syndrome type in the Zhuang nationality and the female hypertension. There was no significant difference in the distribution of TCM syndrome types between Zhuang and Han Chinese (P0.05). There was a significant difference in the distribution of TCM syndromes among Zhuang and Han women (p0.05), (3) the TCM syndrome of Zhuang nationality, (4) The age, history of drinking, family history of cardiovascular and fasting blood glucose were not significant (p0.05). The differences of blood ua, cr, tc, tg, ldl-c and hdl-c in the Zhuang and Han patients with hypertension were of statistical significance (p0.05); (5) The blood biochemical indexes of different TCM syndromes in Zhuang nationality were compared with those of the liver-fire type. There was a difference (p0.01, p0.05) between the deficiency of the yin and the yang, and the difference between the yin deficiency of the yin and the yin and yang (p0.01, p0.05), and the difference between the yin and yang deficiency type of the blood (p0.05). Compared with the hyperactive type of the liver fire, the blood cr of the phlegm-wet type was different (p0.05), and the difference between the yin deficiency and the yin-yang and the yin-yang deficiency-type blood cr (p0.05) was compared with that of the phlegm-dampness type. Compared with the liver-fire type, the type of yin-deficiency-yang-type tc, ldl-c, and hdl-c had a difference (p0.05). Compared with the liver-fire type, both the yin deficiency and the yin-yang deficiency and the yin-yang deficiency type fbs have the difference (p0.05). There was a significant difference between yin deficiency and yin-yang and yin-yang deficiency type blood (p0.01), compared with the blood biochemical index of the type of liver-fire, the yin-deficiency-yang-hyperactivity, and the yin-yang deficiency type of the blood-ua (p0.01), compared with the blood biochemical indexes of the patients with high blood pressure in the Han nationality. Compared with the liver-fire type, the blood cr of the phlegm-dampness type was different (p0.05), and the difference between the yin deficiency and the yin-yang and the yin-yang deficiency-type blood cr (p0.05) and the difference of the distribution of the integral grade of the traditional Chinese medicine syndrome in the Zhuang and Han-Han patients (p0.05). (7) The distribution of TCM syndrome types and syndrome points in Zhuang nationality patients with high blood pressure is mainly manifested as medium-sized, phlegm-dampness and high-type, and the yin-deficiency-yang hyperactive type mainly manifested as the middle and heavy-duty of the TCM syndrome integration. The yin-yang and yin-deficiency type mainly manifested as the heavy-duty of the syndrome of the traditional Chinese medicine; the classification and distribution of the TCM syndrome type and the syndrome integration of the Han-type hypertension patients, the hyperactivity of the liver-fire type, the phlegm-dampness type and the yin-deficiency-yang type are the middle-and medium-sized with the integral of the syndrome of the Chinese medicine, The two-deficiency type of Yin and Yang is the heavy-duty of TCM syndrome, and there is no significant difference in the distribution of TCM syndrome type and syndrome integration in the Zhuang and Han patients (P0.05). Conclusion: (1) The distribution ratio of Chinese traditional Chinese medicine syndrome of Zhuang and Han is different, and the difference between Zhuang and Han type of hypertension is not obvious in the distribution of sex distribution. (2) There is a certain difference in the distribution of Chinese traditional Chinese medicine syndrome of Zhuang and Han nationality in different age groups, which may be related to the evolution of the etiology and pathogenesis of the traditional Chinese medicine. (3) There was some difference in the general condition of cardiovascular disease (BMI, smoking history) and blood biochemical index in Zhuang and Han patients with hypertension. (4) The TCM syndrome type and some blood biochemical indexes of the Zhuang and Han patients with hypertension have a difference, indicating that the TCM syndrome type has a certain correlation with the modern laboratory index. (5) There was no significant difference in the distribution of TCM syndrome in Zhuang and Han patients.
【學(xué)位授予單位】：廣西中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類(lèi)號(hào)】：R259
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