基于數(shù)據(jù)挖掘林麗珠治療乳腺癌用藥規(guī)律研究
發(fā)布時(shí)間:2019-03-31 11:54
【摘要】:目的:基于"中醫(yī)傳承輔助平臺(tái)"(V2.5)軟件,探討林麗珠教授治療乳腺癌的用藥規(guī)律。方法:收集林麗珠教授治療乳腺癌的處方,采用關(guān)聯(lián)規(guī)則apriori算法、復(fù)雜系統(tǒng)熵聚類等數(shù)據(jù)挖掘方法分析其治療乳腺癌的用藥規(guī)律。結(jié)果:對(duì)篩選出的149個(gè)處方進(jìn)行分析,確定處方中藥物的使用頻次和藥物之間的關(guān)聯(lián)規(guī)則,挖掘出18個(gè)核心組合和9首新處方。結(jié)論:林麗珠教授認(rèn)為乳腺癌的病機(jī)以氣郁氣虛為本,痰濁瘀血為標(biāo),臨床多用理氣、健脾、化痰、通絡(luò)之品,體現(xiàn)其"理氣補(bǔ)氣,祛痰通絡(luò)"的學(xué)術(shù)思想。
[Abstract]:Objective: based on the software of traditional Chinese Medicine inheritance Assistance platform (V2.5), this paper discusses the rule of medicine used by Professor Lin Lizhu in the treatment of breast cancer. Methods: the prescription of Professor Lin Lizhu in treating breast cancer was collected, and the rule of drug use in breast cancer was analyzed by using association rule apriori algorithm and complex system entropy clustering and other data mining methods. Results: the 149 prescriptions selected were analyzed to determine the frequency of drug use and the association rules between drugs. 18 core combinations and 9 new prescriptions were excavated. Conclusion: professor Lin Lizhu believes that the pathogenesis of breast cancer is based on qi depression and qi deficiency, phlegm turbidity and blood stasis as standard, clinical use of regulating qi, invigorating spleen, resolving phlegm and clearing collaterals, reflecting its academic thought of "regulating qi and tonifying qi and removing phlegm and clearing collaterals".
【作者單位】: 廣州中醫(yī)藥大學(xué)第一臨床醫(yī)學(xué)院;廣州中醫(yī)藥大學(xué)第一附屬醫(yī)院;
【基金】:廣東省大學(xué)生創(chuàng)新創(chuàng)業(yè)訓(xùn)練計(jì)劃項(xiàng)目(201610572060)-基于無(wú)監(jiān)督數(shù)據(jù)挖掘的林麗珠教授治療四大惡性腫瘤用藥規(guī)律研究
【分類號(hào)】:R273
[Abstract]:Objective: based on the software of traditional Chinese Medicine inheritance Assistance platform (V2.5), this paper discusses the rule of medicine used by Professor Lin Lizhu in the treatment of breast cancer. Methods: the prescription of Professor Lin Lizhu in treating breast cancer was collected, and the rule of drug use in breast cancer was analyzed by using association rule apriori algorithm and complex system entropy clustering and other data mining methods. Results: the 149 prescriptions selected were analyzed to determine the frequency of drug use and the association rules between drugs. 18 core combinations and 9 new prescriptions were excavated. Conclusion: professor Lin Lizhu believes that the pathogenesis of breast cancer is based on qi depression and qi deficiency, phlegm turbidity and blood stasis as standard, clinical use of regulating qi, invigorating spleen, resolving phlegm and clearing collaterals, reflecting its academic thought of "regulating qi and tonifying qi and removing phlegm and clearing collaterals".
【作者單位】: 廣州中醫(yī)藥大學(xué)第一臨床醫(yī)學(xué)院;廣州中醫(yī)藥大學(xué)第一附屬醫(yī)院;
【基金】:廣東省大學(xué)生創(chuàng)新創(chuàng)業(yè)訓(xùn)練計(jì)劃項(xiàng)目(201610572060)-基于無(wú)監(jiān)督數(shù)據(jù)挖掘的林麗珠教授治療四大惡性腫瘤用藥規(guī)律研究
【分類號(hào)】:R273
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